Cisplatin News and Research

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Study reveals time taken for DNA repair after chemotherapy

In the time it takes for an Amazon Prime delivery to arrive, cells damaged by chemotherapy can almost completely fix their most important DNA. That is the case in the livers of mice at least, according to a new study.

2 Jul 2019

Study identifies proteins that interact with processes regulating gene p53

Scientists at VCU Massey Cancer Center have discovered that the loss of a protein called DBC1 in breast cancer cells leads to the dysregulation of normal anti-cancer functions, contributing to cancer cell growth and resistance to therapies.

24 Jun 2019

Researchers discover new hybrid molecules that could act as anti-cancer agents

Researchers from NYU Abu Dhabi's chemistry program and colleagues from the University's biology program have developed and studied the biological activity of five new, metal-organic hybrid knotted molecules, termed metal-organic trefoil knots.

23 May 2019

Novel fluorescence imaging system helps surgeons remove small ovarian tumors

Ovarian cancer is usually diagnosed only after it has reached an advanced stage, with many tumors spread throughout the abdomen.

24 Apr 2019

Cause of cancer is 'written' in our DNA as unique 'fingerprints'

Scientists have discovered that the cause of cancer is “written” within the DNA of tumors, a finding that could help doctors to decide on the best treatment for a patient.

16 Apr 2019

New combination therapy found to be well tolerated in patients with aggressive brain tumor

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients.

30 Mar 2019

Novel ratiometric fluorescent probe for studying cellular activity of anticancer drug

NUS chemists have developed a novel ratiometric fluorescent probe for studying cellular activity of the clinically important anticancer drug cisplatin for next generation drug development.

21 Feb 2019

Platinum nanoparticles show selective toxicity against liver cancer cells

In recent years, the number of targeted cancer drugs has continued to rise. However, conventional chemotherapeutic agents still play an important role in cancer treatment.

15 Feb 2019

Researchers unravel path of metallodrug in a breast cancer cell

Some types of cancer cannot be treated with classical chemotherapy. Scientists from Inserm, CNRS, Sorbonne University, PSL university, University Grenoble Alpes and ESRF, the European Synchrotron, are working on a metallorganic molecule as an antitumor drug.

4 Feb 2019

Clinigen, Accord Healthcare extend exclusive European clinical trial supply agreement

Clinigen Group plc, the global pharmaceutical and services company, announces that its Clinical Trial Service business has extended its exclusive European clinical trial supply agreement with Accord Healthcare. Clinigen is also offering pharma companies an ‘on demand’ service to Accord’s products, a first for the industry.

From Clinigen Group 11 Jan 2019

Cigarette smoking linked with poor outcomes in bladder cancer patients

In a study of patients with muscle-invasive bladder cancer who had undergone radical cystectomy, cigarette smoking was linked with poor response to cisplatin-based chemotherapy.

9 Jan 2019

Study provides information about chemotherapeutic drugs binding to plasma proteins

Chemotherapy is use of drugs to cure a disease but more specifically, it refers to drug therapy for cancer. Cancer chemotherapy can be done with a single drug or a combination of drugs and is usually systematic in nature, that is to say that a drug is administered through the blood circulation to eliminate cancer cells in many parts of the body.

21 Dec 2018

Mannose - nutritional supplement, could slow some cancers

Mannose is a sugary nutritional supplement that has shown promise in slowing down the growth of certain cancers in laboratory mice. The results of the five year-long study from Glasgow were published in the latest issue of the journal Nature.

21 Nov 2018

Nutritional supplement can slow cancer growth and enhance effects of chemotherapy

Mannose sugar, a nutritional supplement, can both slow tumor growth and enhance the effects of chemotherapy in mice with multiple types of cancer.

21 Nov 2018

Sugar supplement shown to slow tumor growth and enhance chemotherapy

Mannose, a type of sugar, has been shown to slow tumor growth and enhance chemotherapy in mouse models of certain cancers.

21 Nov 2018

Advances in radiation treatment help prolong, improve lives of people with anal cancer

Two recent studies find advances in radiation therapy are helping to prolong or improve the lives of people with anal cancer, including those whose cancer has advanced to stage IV.

8 Nov 2018

Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

Treating pre-cancerous stem cells at an early stage could be key to preventing bowel cancer in people born with a very high risk of the disease, according to a study in mice presented at the 2018 NCRI Cancer Conference.

7 Nov 2018

PPM1D gene confers a survival advantage to stem cells after chemotherapy

Chemotherapy has been associated with increased risk of leukemia years after the treatment, but what leads to that association is not clear.

2 Nov 2018

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

With a pair of RO1 grants from the National Institutes of Health, pain researcher Daniela Salvemini, Ph.D., will embark on two new research projects, studying chemotherapy-induced cognitive impairment, or "chemo brain," symptoms and unwanted side effects of opioids.

23 Oct 2018

Immunotherapy with pembrolizumab extends survival in metastatic or recurrent head and neck cancer

Immunotherapy with pembrolizumab improves survival in patients with head and neck cancer that has recurred or metastasized, according to late-breaking results from the KEYNOTE-048 study reported at the ESMO 2018 Congress in Munich.

22 Oct 2018

Cisplatin News and Research

Study reveals time taken for DNA repair after chemotherapy

Study identifies proteins that interact with processes regulating gene p53

Researchers discover new hybrid molecules that could act as anti-cancer agents

Novel fluorescence imaging system helps surgeons remove small ovarian tumors

Cause of cancer is 'written' in our DNA as unique 'fingerprints'

New combination therapy found to be well tolerated in patients with aggressive brain tumor

Novel ratiometric fluorescent probe for studying cellular activity of anticancer drug

Platinum nanoparticles show selective toxicity against liver cancer cells

Researchers unravel path of metallodrug in a breast cancer cell

Clinigen, Accord Healthcare extend exclusive European clinical trial supply agreement

Cigarette smoking linked with poor outcomes in bladder cancer patients

Study provides information about chemotherapeutic drugs binding to plasma proteins

Mannose - nutritional supplement, could slow some cancers

Nutritional supplement can slow cancer growth and enhance effects of chemotherapy

Sugar supplement shown to slow tumor growth and enhance chemotherapy

Advances in radiation treatment help prolong, improve lives of people with anal cancer

Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

PPM1D gene confers a survival advantage to stem cells after chemotherapy

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

Immunotherapy with pembrolizumab extends survival in metastatic or recurrent head and neck cancer

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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