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FDA grants acceptance to application for selumetinib as treatment for neurofibromatosis

AstraZeneca and MSD (Merck) announced today that the U.S. Food and Drug Administration (FDA) has granted acceptance to file status of its application for the MEK inhibitor selumetinib, for use in patients with plexiform neurofibromas, a common manifestation in the disease neurofibromatosis type one (NF1).

14 Nov 2019

Simulation-based approach to target epilepsy enters into clinical trial

In what represents a major milestone on the path to clinical application, a novel method to improve outcomes of Epilepsy surgery has now received approval for clinical testing in 13 French hospitals.

9 Nov 2019

Potential side effects increase in children with use of common reflux aids, study shows

Proton Pump Inhibitors (PPIs) -- such as Prilosec, Protonix and Nexium, have long been one of the most prescribed medications in the country to aid in the reduction of stomach acid.

7 Nov 2019

Vaccine for Lassa fever set to enter clinical testing in humans

There is currently no vaccine for the Lassa arenavirus, which causes Lassa fever. This hemorrhagic fever, endemic in West Africa, infects up to 300,000 people each year.

24 Oct 2019

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

A new cancer clinical trial has opened at the M Health Fairview University of Minnesota Medical Center that leverages the groundbreaking research on stem cells and natural killer cells done at the Masonic Cancer Center and applies it to attack acute myeloid leukemia and B-cell lymphoma.

21 Oct 2019

Vitamin D oral sprays equally effective as taking a tablet

Taking vitamin D by oral spray is just as effective as taking a tablet, research from the University of Sheffield has found.

15 Oct 2019

New cancer treatment developed at Yale

Scientists at Yale have developed a method that assists the immune system in identifying and eliminating cancer cells that may be missed by other forms of immunotherapies.

15 Oct 2019

NIH grants boost rare diseases research efforts

Of an estimated 6,500 to 7,000 known rare diseases, only a fraction - maybe 5% - have U.S. Food and Drug Administration-approved treatments.

4 Oct 2019

Researchers make breakthrough in gene therapy for sickle cell disease

Researchers at the National Institutes of Health have developed a new and improved viral vector--a virus-based vehicle that delivers therapeutic genes--for use in gene therapy for sickle cell disease.

2 Oct 2019

NIAID initiates new Collaborative Influenza Vaccine Innovation Centers program

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has initiated the Collaborative Influenza Vaccine Innovation Centers program, a new network of research centers that will work together in a coordinated, multidisciplinary effort to develop more durable, broadly protective and longer-lasting influenza vaccines.

30 Sep 2019

US Government supports Kinoxis Therapeutics to end opioid addiction

Kinoxis Therapeutics has been awarded a grant for a potential of up to $US4.6 million ($6.8 million) under the USA National Institutes of Health Helping to End Addiction Long-Term, or the NIH HEAL Initiative.

30 Sep 2019

New lab-on-a-chip system quickly identifies health aspects of a person's immune system

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a lab-on-a-chip system that can identify the health aspects of a person's immune system from a drop of their blood, within minutes.

25 Sep 2019

UMSOM receives landmark contract from NIAID for influenza research

Kathleen Neuzil, MD, MPH, Professor of Medicine and Pediatrics and Director of the Center for Vaccine Development and Global Health at the University of Maryland School of Medicine and Dean E. Albert Reece, MD, PhD, MBA, announced that CVD has been awarded a contract from the National Institute of Allergy and Infectious Diseases, with total funding up to more than $200 million over seven years if all contract options are exercised.

20 Sep 2019

Discovery of combination protein leads to first-in-human clinical trial for leukemia

The discovery of tri-specific natural killer engagers (TriKE™), a combination protein that bridges an immune cell and a tumor cell to drive tumor cell killing power exponentially, has led to a new Phase I, first-in-human study to treat leukemia.

20 Sep 2019

CDC warns against vaping after series of lung-disease cases

E-cigarette use, also known as vaping, has become popular across all ages. Hundreds of people across the country have been sickened by a severe lung disease linked to e-cigarette use. The Centers for Disease Control and Prevention (CDC) warns the public not to use e-cigarettes due to the potential damage to the lungs.

9 Sep 2019

Novel self-monitoring solution can be an efficient tool in managing uncontrolled asthma

A study by researchers at Karolinska Institutet shows that a treatment adjustment algorithm based on lung function and symptoms in a mobile phone can be an efficient tool in managing uncontrolled asthma.

3 Sep 2019

Cracking the code of a recurrent brain cancer

One of the most common brain cancers in children, Sonic Hedgehog (SHH) medulloblastoma, also is one of the more survivable for most kids. Unfortunately, for a subset of patients the cancer resists treatment and relapses with a vengeance to then turn deadly.

30 Aug 2019