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Reduction of prenatal depression associated with higher full-term birth rates

The effect of lowering prenatal mother depression on gestational duration.

25 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

Study links poor heart health in Black women to midlife cognitive decline

A new study has found that Black women with poor cardiovascular health may face an elevated risk of early signs of cognitive decline in midlife.

24 Apr 2024

Better cardiovascular health among middle-aged Black women linked to less decline in cognition

Better heart health was linked to less decline in mental processing speed and cognition among middle-aged Black women, although not among middle-aged white women, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

24 Apr 2024

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

The U.S. Food and Drug Administration (FDA) has approved the immunotherapy-boosting drug N-803, which is marketed under the brand name Anktiva, to be used in combination with the immunotherapy Bacillus Calmette-Guerin (BCG) for the treatment of patients with BCG-unresponsive non–muscle-invasive bladder cancer.

23 Apr 2024

CN Bio raises $21 million USD in first close of Series B investment round

Bayland Capital and founding shareholder, CN Innovations Holdings Ltd, to invest $10 M and $5.5 M, respectively. Investment will expand product development and scaling of the organization to meet increased demand for Organ-on-a-Chip (OOC) solutions.

23 Apr 2024

The vital role of therapeutic alliances in psychedelic treatment

Drug effects have dominated the national conversation about psychedelics for medical treatment, but a new study suggests that when it comes to reducing depression with psychedelic-assisted therapy, what matters most is a strong relationship between the therapist and study participant.

23 Apr 2024

Korean fermented food Doenjang shows promise in alleviating menopausal symptoms

Study compares the effects of traditional versus commercial Korean Doenjang on menopausal symptoms, finding that traditional variants with high beneficial microorganisms are more effective in reducing these symptoms and improving cardiovascular and gut health.

21 Apr 2024

Dietary treatments outperform medications for IBS management

Dietary treatment is more effective than medications in irritable bowel syndrome (IBS). These are the findings of a study conducted at the University of Gothenburg.

18 Apr 2024

Researchers receive NIH grant to help develop gene therapy for HIV

Researchers at Washington University School of Medicine in St. Louis have received a $6.2 million grant from the National Institutes of Health (NIH) to develop a gene therapy that would modify the immune system's B cells to spur them to produce broadly neutralizing antibodies against HIV.

18 Apr 2024

New trials show promise for immune checkpoint blockers in early-stage lung cancer

A dendritic cell (DC) vaccine targeting patient-specific neoantigens to patients with resected non-small cell lung cancer (NSCLC).

18 Apr 2024

Breakthrough imaging method enhances precision in prostate cancer treatment

A novel SPECT/CT acquisition method can accurately detect radiopharmaceutical biodistribution in a convenient manner for prostate cancer patients, opening the door for more personalized treatment.

17 Apr 2024

Penn State study examines how a person's telomeres are affected by caloric restriction

Penn State researchers may have uncovered another layer of complexity in the mystery of how diet impacts aging.

17 Apr 2024

Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

17 Apr 2024

TAME trial findings offer new hope for children with malnutrition enteropathy

A comparison of treatments for malnutrition enteropathy, caused by severe acute malnutrition (SAM), has found evidence supporting the use of treatments to enhance the healing of mucosal membranes and reduce inflammation in the gut to improve the outcomes of children affected by long-term health consequences of a period of malnutrition.

17 Apr 2024

Online video therapy comparable to in-person visits after thumb CMC arthroplasty

For patients undergoing carpometacarpal (CMC) joint surgery for treatment of thumb osteoarthritis, the use of online video instruction for postoperative hand therapy is associated with outcomes similar to in-person therapy visits – while substantially reducing travel time and distance, reports a clinical trial in The Journal of Bone & Joint Surgery.

17 Apr 2024

Universities collaborate on $15 million project investigating inflammation's role in cardiac and brain diseases

Research teams from Northwestern University Chicago Campus, University of Michigan and University of Pittsburgh will lead a $15 million project dedicated to studying inflammation's role in cardiac and brain diseases.

17 Apr 2024

Combined chemohormonal therapy for locally advanced prostate cancer offers extended control of PSA levels

For patients with locally advanced prostate cancer, combined treatment with chemotherapy and hormonal therapy offers extended control of prostate-specific antigen (PSA) levels, compared to hormonal therapy alone, reports a study in the April issue of The Journal of Urology, an Official Journal of the American Urological Association.

17 Apr 2024

Renaissance of "food as medicine" in modern clinical trials

Priya Venkatesan discusses in Nature Medicine how dietary interventions can prevent or delay diseases, highlighting the reemergence of "food as medicine" in modern clinical trials.

17 Apr 2024

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Clinical Trial News and Research

Reduction of prenatal depression associated with higher full-term birth rates

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Study links poor heart health in Black women to midlife cognitive decline

Better cardiovascular health among middle-aged Black women linked to less decline in cognition

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

CN Bio raises $21 million USD in first close of Series B investment round

The vital role of therapeutic alliances in psychedelic treatment

Korean fermented food Doenjang shows promise in alleviating menopausal symptoms

Dietary treatments outperform medications for IBS management

Researchers receive NIH grant to help develop gene therapy for HIV

New trials show promise for immune checkpoint blockers in early-stage lung cancer

Breakthrough imaging method enhances precision in prostate cancer treatment

Penn State study examines how a person's telomeres are affected by caloric restriction

Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

TAME trial findings offer new hope for children with malnutrition enteropathy

Online video therapy comparable to in-person visits after thumb CMC arthroplasty

Universities collaborate on $15 million project investigating inflammation's role in cardiac and brain diseases

Combined chemohormonal therapy for locally advanced prostate cancer offers extended control of PSA levels

Renaissance of "food as medicine" in modern clinical trials

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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