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Launch of Zorbtive for use in the treatment of patients with short bowel syndrome

Serono, Inc., the US affiliate of Serono, announced today the launch of Zorbtive™ [somatropin (rDNA origin) for injection] for use in the treatment of patients with short bowel syndrome.

25 May 2004

X-ray beams could kick start genes into fighting cancer

X-ray beams could kick start genes into fighting cancer as an exciting new way of targeting therapy against the disease, according to new research in the Journal of Gene Medicine.

25 May 2004

Heart failure is a leading cause of death and nearly 5 million people in the United States suffer from it

“Heart failure is a leading cause of death and nearly 5 million people in the United States suffer from it,” says Mariell Jessup, MD, Professor of Medicine and Medical Director of the Heart Failure and Transplantation Program at the Hospital of the University of Pennsylvania (HUP).

24 May 2004

Trial shows Daclizumab therapy improves multiple sclerosis outcome

A small clinical trial of patients with multiple sclerosis (MS) who did not respond to interferon alone found that adding the human antibody daclizumab improved patient outcome. Patients who received the combined therapy had a 78 percent reduction in new brain lesions and a 70 percent reduction in total lesions, along with other significant clinical improvements.

24 May 2004

Significant symptom relief reported in clinical trial patients with irritable bowel syndrome

Solvay Pharmaceuticals unveiled this week results from a six-month study of both male and female patients and from a subgroup analysis of males with Irritable Bowel Syndrome with Diarrhea predominance (IBS-D).

24 May 2004

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Researchers in the department of ophthalmology at the University of Arizona College of Medicine in Tucson played an important role in the development of Restasis, the first alternative to artificial tears for the treatment of dry eye syndrome.

21 May 2004

Pacemaker-type device and medicines reduce hospital stays and death rates

A nationwide clinical trial of more than 1,600 heart failure patients showed that when medicines are combined with the use of a pacemaker-type device that resynchronizes both sides of the heart, hospital stays and death rates drop significantly.

20 May 2004

Dietary supplement reduces body fat mass in overweight adults by as much as nine percent

A study to be published in the June issue of The American Journal of Clinical Nutrition concludes that the dietary supplement, conjugated linoleic acid (CLA), reduces body fat mass in overweight, but otherwise healthy, adults by as much as nine percent.

20 May 2004

Study has important implications for African Americans who suffer from high blood pressure

A new study has important implications for the millions of African Americans who suffer from high blood pressure. The study, AADVANCE, shows Diovan HCT(R) (valsartan and hydrochlorothiazide) lowers blood pressure in African Americans to aggressive recommended target blood pressure goals as effectively as amlodipine.

20 May 2004

CRT implantable defibrillators significantly reduce hospitalization rates and extend lives

Researchers at the University of Colorado Health Sciences Center have announced the findings of a large-scale clinical trial for patients with late-stage heart failure. Results showed that cardiac resynchronization therapy (CRT) from implantable pacemaker-like devices or CRT combined with an implantable defibrillator (CRT-D), when used in addition to optimal drug therapy, reduced significantly the mortality and first hospitalization rate when compared to drug therapy alone. CRT-D also substantially lowered mortality.

19 May 2004

$First drug approved for hormone refractory prostate cancer that has shown a survival benefit$

First drug approved for hormone refractory prostate cancer that has shown a survival benefit

The the Food and Drug Administration (FDA) approved Taxotere (docetaxel), injection in combination with prednisone ( a steroid), for the treatment of patients with advanced metastatic prostate cancer. This is the first drug approved for hormone refractory prostate cancer that has shown a survival benefit.

19 May 2004

Clinical trial of traditional Chinese medicine for the treatment of male infertility

Traditional Chinese Medicine (TCM) researcher Jann Mehmet knows the effectiveness of acupuncture and Chinese herbal medicine in treating male infertility. Now she is putting her observations to the test in a formal clinical trial of the benefits of TCM, the first time such a study has been conducted in Australia - or overseas.

18 May 2004

Study comparing the efficacy of REMICADE® to Azathioprine alone and in combination With REMICADE®

Centocor, Inc., and Schering-Plough Corporation announced today the initiation of the SONIC (Study of Immunomodulator Naive patients in Crohn's Disease) trial that will evaluate the efficacy of REMICADE® (infliximab) versus azathioprine, a conventional immunosuppressive agent, alone and versus the combination of both drugs for the treatment of patients with Crohn's disease.

18 May 2004

Discovery of the gene for Cornelia de Lange syndrome

An international team of researchers has discovered the gene for Cornelia de Lange syndrome, a disabling, multisystem genetic disease that affects an estimated one in 10,000 children. The finding is expected to lead to a genetic test, enabling rapid and definitive diagnosis of the syndrome, as well as prenatal testing for families who already have one child with the disease.

17 May 2004

Women are not checking for colon cancer

Many women who regularly get checked for breast cancer and cervical cancer still don’t go for a test that could save them from another big killer -- colon cancer – according to new University of Michigan research. But perhaps their mammogram and Pap smear appointments could be used as “teachable moments” to help prompt them to get their colons checked, the researchers suggest.

15 May 2004

The Stroke Association have found that surgery can halve the risk of a stroke

Scientists funded by the Medical Research Council (MRC) and The Stroke Association have found that surgery can halve the risk of a stroke for people who have significant narrowing of the main artery carrying blood to the brain. Their findings, published in this week’s The Lancet, are the result of a large-scale international clinical trial.

14 May 2004

Phase 3 trial of Ceplene in acute myeloid leukemia meets primary trial endpoint

Maxim Pharmaceuticals has announced the results of an international Phase 3 clinical trial testing the combination of Ceplene (TM) plus interleukin-2 (IL-2) in 320 patients with acute myeloid leukemia (AML) in complete remission.

12 May 2004

Cardiovascular marketing budgets hit $200 Million

Pharmaceutical companies spend more to support a cardiovascular compound's development and commercialization than other therapeutic products

12 May 2004

Thoratec gets FDA approval for increased enrollment and Medicare expansion for heart pump

Thoratec Corporation, a manufacturer of products to treat cardiovascular disease, has announced the expansion of its Phase I feasibility trial for the HeartMate(R) II left ventricular assist system (LVAS).

12 May 2004

$Trial of a drug derived from the puffer fish for treatment of refractory cancer pain$

Trial of a drug derived from the puffer fish for treatment of refractory cancer pain

Investigators involved in the pivotal clinical trial of TectinTM enrolled and dosed the first of up to 150 patients that will participate in the study. It is one of the largest Canadian clinical trials to evaluate the efficacy and safety of a drug for treatment of medically refractory cancer pain, and will take place in up to 25 treatment centres across Canada.

11 May 2004

Clinical Trial News and Research

Launch of Zorbtive for use in the treatment of patients with short bowel syndrome

X-ray beams could kick start genes into fighting cancer

Heart failure is a leading cause of death and nearly 5 million people in the United States suffer from it

Trial shows Daclizumab therapy improves multiple sclerosis outcome

Significant symptom relief reported in clinical trial patients with irritable bowel syndrome

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Pacemaker-type device and medicines reduce hospital stays and death rates

Dietary supplement reduces body fat mass in overweight adults by as much as nine percent

Study has important implications for African Americans who suffer from high blood pressure

CRT implantable defibrillators significantly reduce hospitalization rates and extend lives

First drug approved for hormone refractory prostate cancer that has shown a survival benefit

Clinical trial of traditional Chinese medicine for the treatment of male infertility

Study comparing the efficacy of REMICADE® to Azathioprine alone and in combination With REMICADE®

Discovery of the gene for Cornelia de Lange syndrome

Women are not checking for colon cancer

The Stroke Association have found that surgery can halve the risk of a stroke

Phase 3 trial of Ceplene in acute myeloid leukemia meets primary trial endpoint

Cardiovascular marketing budgets hit $200 Million

Thoratec gets FDA approval for increased enrollment and Medicare expansion for heart pump

Trial of a drug derived from the puffer fish for treatment of refractory cancer pain

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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