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Trial: Physiotherapy after dislocated shoulder is no better than a single session of advice

Routinely referring patients to a tailored programme of physiotherapy after a dislocated shoulder is no better than a single session of advice, supporting materials and the option to self-refer to physiotherapy, finds a clinical trial published by The BMJ today.

27 Jan 2024

A certain type of chemotherapy found to improve the immune system's ability to fight off bladder cancer

Tisch Cancer Institute researchers discovered that a certain type of chemotherapy improves the immune system's ability to fight off bladder cancer, particularly when combined with immunotherapy, according to a study published in Cell Reports Medicine in January.

27 Jan 2024

Immunotherapy breakthrough: Pembrolizumab extends time to recurrence in aggressive bladder cancer

Patients with muscle-invasive urothelial cancer and a high risk of recurrence after surgery may have a new treatment option.

27 Jan 2024

Clinical study supports the long-lasting impacts of typhoid conjugate vaccine

A single dose of the typhoid conjugate vaccine, Typbar TCV, provides lasting efficacy in preventing typhoid fever in children ages 9 months to 12 years old, according to a new study conducted by researchers at University of Maryland School of Medicine's (UMSOM) Center for Vaccine Development and Global Health (CVD) and led by in-country partners at the Malawi-Liverpool Wellcome Trust (MLW) Clinical Research Programme.

25 Jan 2024

UCL's neuro research to be supported by e-money venture Science Card

A UCL research team developing an artificial fiber technology to accelerate neurodegenerative disease clinical trials will be one of the first studies supported by e-money venture Science Card.

25 Jan 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs -; with the addition of an also already FDA-approved complement inhibitor -; are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

The drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duchenne muscular dystrophy (DMD).

25 Jan 2024

Study shows effectiveness of gene therapy in treating congenital deafness

A new study co-led by investigators from Mass Eye and Ear, a member of Mass General Brigham, demonstrated the effectiveness of a gene therapy towards restoring hearing function for children suffering from hereditary deafness.

24 Jan 2024

Researchers secure $1.5 million grant to eliminate barriers from cervical cancer prevention

A research team from LSU LCMC Health Cancer Center has been awarded a $1.5 million grant to eliminate barriers from cervical cancer prevention. The five-year program combines a $1.2 million award from the American Cancer Society and $75,000 a year for five years investment from LSU Health New Orleans.

24 Jan 2024

Researchers uncover a gene that causes heart defects in Down syndrome

Researchers at the Francis Crick Institute and UCL have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21.

24 Jan 2024

European consortium awarded €6.5M to study psychedelic-assisted therapy

A European consortium of 19 partners has been awarded over €6.5M by the European Union to study psilocybin to treat psychological distress in people with progressive incurable illnesses requiring palliative care.

24 Jan 2024

Combination drug therapy beats solo treatment for aggressive prostate cancer relapse

Combining testosterone-blocking drugs in patients with prostate cancer relapse prevents the spread of cancer better than treatment with a single drug, a multi-institution, Phase 3 clinical trial led by UC San Francisco researchers has found.

23 Jan 2024

Blood pressure drug could help lower anxiety for kids and young adults with ASD

A new study at the University of Missouri's Thompson Center for Autism and Neurodevelopment found that propranolol, a medication that treats high blood pressure, can also help lower anxiety for kids and young adults with autism spectrum disorder (ASD).

23 Jan 2024

Scientists identify a new approach to treating sarcoidosis

A research team led by Georg Stary (Medical University of Vienna and CeMM) has identified a new approach to treating the inflammatory disease sarcoidosis.

23 Jan 2024

APOE4 genetic risk factors for Alzheimer's disease associated with increased risk of subclinical atherosclerosis

Scientists at the Centro Nacional de Investigaciones Cardiovasculares in Madrid have found that one of the most potent genetic risk factors for Alzheimer disease, apolipoprotein E4 (APOE4), is also associated with an increased risk of developing subclinical atherosclerosis in middle age.

23 Jan 2024

Study identifies genetic variants that influence response to preterm birth treatment

A UC San Francisco-led study has for the first time identified genetic variants that predict whether patients will respond to treatment for preterm birth, a condition that affects one in 10 infants born in the United States.

22 Jan 2024

Thinning brain tissue predicts dementia up to a decade before symptoms

A ribbon of brain tissue called cortical gray matter grows thinner in people who go on to develop dementia, and this appears to be an accurate biomarker of the disease five to 10 years before symptoms appear, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported.

22 Jan 2024

Nicotine patches and e-cigarettes in pregnancy: A deep dive into risks and outcomes

Researchers examined the safety of e-cigarettes and nicotine-containing patches during pregnancy.

22 Jan 2024

Annexin-A1 targeted therapy beats several cancers

A new study published in Nature's cancer journal Oncogene highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein which is overexpressed in several cancer types and promotes tumour progression.

19 Jan 2024

Clinical trial shows MRI and tracking-guided delivery of magnetic stimulation to brains of people with severe depression eases symptoms

Researchers performed a randomized clinical trial to compare resting-state functional magnetic resonance imaging connectivity-guided intermittent theta burst stimulation vs. repetitive transcranial magnetic stimulation for therapy-resistant depression.

19 Jan 2024

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Clinical Trial News and Research

Trial: Physiotherapy after dislocated shoulder is no better than a single session of advice

A certain type of chemotherapy found to improve the immune system's ability to fight off bladder cancer

Immunotherapy breakthrough: Pembrolizumab extends time to recurrence in aggressive bladder cancer

Clinical study supports the long-lasting impacts of typhoid conjugate vaccine

UCL's neuro research to be supported by e-money venture Science Card

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

Study shows effectiveness of gene therapy in treating congenital deafness

Researchers secure $1.5 million grant to eliminate barriers from cervical cancer prevention

Researchers uncover a gene that causes heart defects in Down syndrome

European consortium awarded €6.5M to study psychedelic-assisted therapy

Combination drug therapy beats solo treatment for aggressive prostate cancer relapse

Blood pressure drug could help lower anxiety for kids and young adults with ASD

Scientists identify a new approach to treating sarcoidosis

APOE4 genetic risk factors for Alzheimer's disease associated with increased risk of subclinical atherosclerosis

Study identifies genetic variants that influence response to preterm birth treatment

Thinning brain tissue predicts dementia up to a decade before symptoms

Nicotine patches and e-cigarettes in pregnancy: A deep dive into risks and outcomes

Annexin-A1 targeted therapy beats several cancers

Clinical trial shows MRI and tracking-guided delivery of magnetic stimulation to brains of people with severe depression eases symptoms

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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