Clostridium News and Research

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Eye disease medication lowers death rate among Ethiopian children

Children in Ethiopia who received the antibiotic azithromycin as a method for controlling the contagious eye disease trachoma had a lower odds of death compared to children who did not receive the antibiotic, according to a study in the September 2 issue of JAMA.

2 Sep 2009

Bioneutral Group holds scientific and business discussions with major health care companies

BioNeutral Group, Inc. (“BioNeutral”) (OTCBB:BONU), a specialty chemical technology based Life Science Company, announced discussions with four of the world’s largest health care companies.

25 Aug 2009

Norovirus controlled on cruise ship Marco Polo with vaporisation process by Activ8

The cruise ship Marco Polo, whose round-Britain cruise had to be cancelled because hundreds of passengers became ill with the vomiting bug Norovirus, has been totally disinfected by SitexOrbis' revolutionary infection control fogging service in just 5 hours at the Tilbury docks.

19 Aug 2009

New online tool to help nurses prevent the 10 "Never Events"

Elsevier, a world leader in healthcare and medical publishing and online solutions, today announced the availability of a new online tool within Mosby's Nursing Consult designed to help nurses prevent the 10 "Never Events" identified by the Centers for Medicare and Medicaid Services (CMS) in an October 2008 fact sheet.

10 Aug 2009

Machine designed to reduce infections and cut back on expensive "disposables"

Johns Hopkins experts in applied physics, computer engineering, infectious diseases, emergency medicine, microbiology, pathology and surgery have unveiled a 7-foot-tall, $10,000 shower-cubicle-shaped device that automatically sanitizes in 30 minutes all sorts of hard-to-clean equipment in the highly trafficked hospital emergency department.

30 Jul 2009

Researchers expose the biology of Clostridium difficile transmission in mice

New research suggests that antibiotic treatment could be asymptomatically inducing the transmission of the healthcare-acquired infection, C. difficile, contributing to the outbreaks that have recently been widely reported in hospitals and other settings. A team of scientists have successfully mirrored the infection cycle of C. difficile by generating a 'mouse hospital' with conditions mimicking the human environment in which C. difficile is transmitted.

20 Jul 2009

Do viruses make bacteria more deadly?

In England and Wales, the national health statistics in 2007 showed that there were 8,324 death certificates which named Clostridium difficile. This is a bacterium which causes severe diarrhoea in humans and animals as the underlying cause of death, a 28% increase from 2006.

22 Jun 2009

New discovery on how botulism paralyzes nerve cells

New structures of a botulism toxin interacting with a mimic of the nerve-cell protein it destroys suggest new ways to block this often-fatal interaction. Indeed, the mimic molecules have such high affinity for the toxin and bind to it so tightly that they themselves could possibly serve as anti-toxin drugs with further modification, the researchers said.

21 Jun 2009

Antibiotics diminish diversity of helpful gutmicrobes

It's common knowledge that a protective navy of bacteria normally floats in our intestinal tracts. Antibiotics at least temporarily disturb the normal balance. But it's unclear which antibiotics are the most disruptive, and if the full array of "good bacteria" return promptly or remain altered for some time.

18 Jun 2009

Old drug Auranofin may lead to new antibiotics

A mineral found at health food stores could be the key to developing a new line of antibiotics for bacteria that commonly cause diarrhea, tooth decay and, in some severe cases, death.

1 Jun 2009

Transmission of MRSA and Clostridium difficile through dogs

In a letter to the Editor of the Journal of Hospital Infection, published by Elsevier, S. Lefebvre and J.S. Weese from the University of Guelph in Canada describe a study that investigated whether MRSA and C.difficile could be passed between pet therapy dogs and patients.

7 May 2009

Optimer Pharmaceuticals receives production patent for Fidaxomicin

Optimer Pharmaceuticals, Inc. has announced that the United States Patent and Trademark Office issued a production patent (U.S. Patent No. 7,507,564) covering steps used in the manufacture of fidaxomicin, which is currently in its second Phase 3 clinical trial for the treatment of Clostridium difficile infection, or CDI.

13 Apr 2009

Targeted approach to kill specific disease-causing bacteria in the mouth

Research to develop a narrow-spectrum antibiotic that can target a particular species of bacteria without harming the other "good" bacteria present was described at the Society for General Microbiology meeting at Harrogate today (Thursday April 2).

1 Apr 2009

Doctors identify patients at high risk of Clostridium difficile

Doctors have developed and validated a clinical prediction rule for recurrent Clostridium difficile ( C. difficile ) infection that was simple, reliable and accurate, and can be used to identify high-risk patients most likely to benefit from measures to prevent recurrence.

1 Apr 2009

FDA approves new indication for Wyeth's Tygacil (tigecycline)

Wyeth Pharmaceuticals, a division of Wyeth has announced that the U.S. Food and Drug Administration (FDA) approved Tygacil (tigecycline), for the treatment of adult patients with community-acquired bacterial pneumonia (CABP) caused by susceptible strains of indicated pathogens.

24 Mar 2009

Clostridium difficile infection in primary care

The epidemiology of Clostridium difficile infection (CDI) is changing rapidly and has been marked by a significant increase in incidence and severity.

23 Mar 2009

New botulinum toxin type A (Reloxin) appears to be well tolerated and may help reduce forehead wrinkles

Injections with a new type of botulinum toxin appears to be well tolerated and may help to improve the appearance of moderate to severe forehead lines with no evidence of diminishing treatment response over 13 months, according to a report in the March/April issue of Archives of Facial Plastic Surgery.

16 Mar 2009

Review of hospital infection control strategies

Hand-washing, a clean environment, appropriate infection barriers and early identification of patients at high risk of colonization with a transmissible microorganism remain the essential measures to prevent and control infection.

16 Mar 2009

Scientists debug Clostridium difficile

An international team of scientists, led by Monash University researchers, has uncovered the workings of a superbug that kills elderly hospital patients worldwide - a discovery that has the potential to save lives and health care systems billions of dollars each year.

2 Mar 2009

Study reveals high level of adverse drug reactions in hospitals

In a study of more than 3,000 patients, researchers at the University of Liverpool have found that one in seven admitted to hospital experience adverse drug reactions to medical treatment.

15 Feb 2009