Cohesin News and Research

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Cohesin is the protein responsible for binding the sister chromatids during mitosis after S phase. At metaphase, most cohesin is removed, except for some at the centromere. At Anaphase, securin, an inhibitory subunit of separase, is hydrolyzed.
Findings set the stage for identifying potential new drug targets, treatment strategies for AML

Findings set the stage for identifying potential new drug targets, treatment strategies for AML

Details about genomic landscapes of AML and endometrial cancer revealed

Details about genomic landscapes of AML and endometrial cancer revealed

Novel Cornelia de Lange syndrome gene discovered

Novel Cornelia de Lange syndrome gene discovered

Researchers identify new gene in Cornelia deLange syndrome

Researchers identify new gene in Cornelia deLange syndrome

HDAC8 gene mutations cause Cornelia deLange syndrome

HDAC8 gene mutations cause Cornelia deLange syndrome

DRCRF names 21 new Damon Runyon Fellows

DRCRF names 21 new Damon Runyon Fellows

Researchers uncover insights into rare genetic disorders

Researchers uncover insights into rare genetic disorders

Researchers identify new functions of cohesin SA1 that are relevant for cancer and CdLS

Researchers identify new functions of cohesin SA1 that are relevant for cancer and CdLS

Major contributing factor to maternal age-associated increase in aneuploidy identified

Major contributing factor to maternal age-associated increase in aneuploidy identified

New insight into infertility in older women

New insight into infertility in older women

Deficiencies in DNA loop formation can cause multiple diseases: Research

Deficiencies in DNA loop formation can cause multiple diseases: Research

Cohesin protein disrupts gene function in Cornelia deLange syndrome

Cohesin protein disrupts gene function in Cornelia deLange syndrome

Chromosome glue repairs damaged DNA

Chromosome glue repairs damaged DNA

Gene found for Cornelia deLange syndrome

Gene found for Cornelia deLange syndrome

New understanding of chromosomal glue

New understanding of chromosomal glue

Protein Mnd2 protects chromosome bonds

Protein Mnd2 protects chromosome bonds

Needling chromosomes yields insights into cell division

Needling chromosomes yields insights into cell division