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GSK, Crucell to test second-generation malaria vaccine

GlaxoSmithKline and drug company Crucell, a division of Johnson & Johnson, will collaborate with the PATH Malaria Vaccine Initiative to test a second-generation malaria vaccine "within the next couple of months," Reuters reports.

8 Jun 2011

Viewpoints: Confronting 'giant' Medicare choices; first lady's anti-obesity campaign; Calif. insurance rules

Sometimes life presents you with a basic philosophical choice. Americans are going to have to confront a giant one over the next several years. It starts in the wonky world of Medicare. ... Democrats have much greater faith in centralized expertise. ... [Republicans] have much greater faith in the decentralized discovery process of the market.

8 Jun 2011

Crucell, GSK and PATH MVI partner to develop second-generation vaccine against malaria

The PATH Malaria Vaccine Initiative (MVI) announced today that it has entered into a collaboration with Dutch biopharmaceutical company Crucell N.V. and GlaxoSmithKline.

7 Jun 2011

PATH malaria vaccine initiative to collaborate with GSK and Crucell in development of 2nd-generation malaria vaccine

The PATH Malaria Vaccine Initiative (MVI) announced today that it has entered into a collaboration with Dutch biopharmaceutical company Crucell N.V. and GlaxoSmithKline (GSK). This collaboration is aimed at developing a second-generation vaccine against malaria—a deadly disease that kills close to 800,000 people annually, most of them young children under age five in Africa. MVI drives the development of malaria vaccines by joining its scientific, managerial, and field expertise with companies, universities, and governments to test potential malaria vaccines and invest in those with the most promise.

6 Jun 2011

Senescent melanoma cells express an inflammatory secretome

Malignant melanoma is a highly aggressive and notoriously chemoresistant form of cancer. In this paper, Ohanna et al. reveal that anti-melanoma drugs may, paradoxically, induce a senescence-associated secretory profile ("secretome") that can ultimately promote metastasis and contribute to melanoma relapse.

6 Jun 2011

UCLA pediatric investigators earn top accolades at TTCF Faculty Presentation Awards

A new therapy for type 1 diabetes? A promising treatment for deadly viruses? Does a common treatment for children with severe infection actually cause more harm than good? These are important questions being investigated by pediatric researchers at Mattel Children's Hospital UCLA.

4 Jun 2011

Climate change can harm indigenous peoples' health

The Canadian Arctic. The Amazonian jungle. The fringes of an African rainforest. These lands are home to some of the most isolated and vulnerable people in the world - the indigenous populations of Canada, Peru and Uganda. Because of their dependence on the land for food and water, indigenous peoples' health is particularly affected by climatic changes. Indeed, they are already seeing dramatic effects due to changing temperatures.

3 Jun 2011

Flu cases rise by 50% in Queensland: Residents alerted

According latest reports, flu cases in Queensland have increased by more than half since last year, causing concern among doctors about an early on-set of flu season. The Australian Medical Association Queensland has revealed close to 1600 cases of flu have been reported across the state this year, with as many as 460 cases reported over the last five weeks alone. They add that that as many as 30 per cent of the flu cases reported were the H1N1 virus, more commonly known as swine flu.

2 Jun 2011

IDF applauds Representatives for Medicare IVIG Access Act

The Immune Deficiency Foundation applauds Representatives Kevin Brady and Doris Matsui and Senators John Kerry and Lamar Alexander for introducing H.R. 1845 and S. 960, both entitled the Medicare IVIG Access Act.

27 May 2011

Gestational high-fat diet programs woman's baby for future diabetes

A high-fat diet during pregnancy may program a woman's baby for future diabetes, even if she herself is not obese or diabetic, says a new University of Illinois study published in the Journal of Physiology.

26 May 2011

Coronary artery disease is a leading cause of death in U.S. women

It's a silent killer, most women don't even know they have it. It's often thought of as a man's disease and may not receive as much attention as other illnesses, but coronary artery disease (CAD) is the leading cause of death in women in the U.S. It is so common that if you combine the number of women who die from the next five leading causes of death it would equal the number of women who die from CAD.

26 May 2011

Concern over vaccine safety prevents parents from vaccinating asthmatic children

Concern over vaccine safety is one of the primary factors preventing parents from having their asthmatic children vaccinated for influenza, or flu, according to Michigan researchers. Parents who do not vaccinate their children are also less likely to view flu as a"trigger" for their child's asthma, the researchers noted.

17 May 2011

FDA warns consumers about look like antimicrobial dietary supplements

The FDA is warning consumers not to use products marketed as dietary supplements that also claim to be antimicrobial (antibiotic, antifungal or antiviral) drugs. These illegal products are falsely promoted with claims to treat illnesses such as upper respiratory infections, sinusitis, pneumonia, bronchitis and the common cold.

16 May 2011

Evidence of damaged baby brains & inadequate anesthetic induced sleep: Conference updates

According to new studies commonly used anesthetics may be causing brain damage in people, especially babies who receive them while their brains are still developing.

15 May 2011

Tips for fighting drug-resistant superbugs

Superbug CRKP is just the latest in emerging strains of drug-resistant bacteria. While new drugs to combat these stealthy microbes like MRSA and CRKP remain in development what can we do to prevent catching and spreading these dangerous bugs?.

13 May 2011

Research shows that cold cognition predicts hot emotion

How useful would it be to anticipate how well someone will control their emotions? To predict how well they might be able to stay calm during stress? To accept critical feedback stoically? Heath A. Demaree, professor of psychology at Case Western Reserve University, finds clues in what psychologists call "hot" and "cold" psychology.

12 May 2011

GSK, NanoBio initiate two NB-001 Phase 3 trials in cold sores

NanoBio Corporation today announced the initiation of two Phase 3 multicenter trials evaluating NB-001 as a topical treatment for cold sores, a step forward in their OTC licensing agreement with GlaxoSmithKline Consumer Healthcare.

12 May 2011

MHI team uses cryoablation to successfully treat atrial fibrillation

The electrophysiology team at the Montreal Heart Institute (MHI) used cryoablation (ablation using cold) to treat a patient suffering from atrial fibrillation, the most common form of cardiac arrhythmia, and one associated with significant morbidity.

From Medtronic 11 May 2011

Scientists unravel how genetic defects can help predict risk of sudden cardiac death

Sudden cardiac death is always a shocking, tragic event, especially when it occurs at a young age. But, for the first time, scientists are unraveling how genetic defects can help predict the risk of dying suddenly in individuals with one of the leading causes of this unfortunate phenomenon.

11 May 2011

16-year-old uses supercomputing network to invent new drug cocktail for cystic fibrosis

While many 16-year-olds are content with PlayStation, Toronto-area student Marshall Zhang used the Canadian SCINET supercomputing network to invent a new drug cocktail which could one day help treat cystic fibrosis.