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New research gives unprecedented view of colorectal cancer genetic makeup

Researchers provided a comprehensive genomic characterization of colorectal carcinoma, a type of cancer that starts in the colon or rectum, through whole-genome sequencing of 2,023 samples, identifying novel driver genes, molecular subgroups, and potential clinical implications.

15 Aug 2024

Diet-derived molecules identified as main drivers of young-onset colorectal cancer risk

A new Cleveland Clinic study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat.

14 Aug 2024

Impact of physical activity on gut microbiota in irritable bowel syndrome

The impact of different types and intensities of physical exercise on the gut microbiota and symptom alleviation in patients with irritable bowel syndrome.

14 Aug 2024

Can how often you eat meat raise your risk of colorectal cancer?

Study shows that high processed meat intake significantly increases colorectal neoplasm risk, with effects equivalent to a 19 percentile increase in genetic risk scores, while red meat consumption shows no significant association.

11 Aug 2024

Breakthrough study uncovers TIP60’s role in DNA access and disease mechanisms

To transcribe the information contained in our genes or to repair the dozens of breaks that occur daily in our DNA, our enzymes must be able to directly access the DNA to perform their functions.

9 Aug 2024

Gene activity can predict severe side effects from melanoma treatment

An activity pattern in certain genes responsible for building proteins known as spleen tyrosine kinases can predict which melanoma patients are likely to have severe side effects from immunotherapy designed to treat the most deadly skin cancer, a new study shows.

8 Aug 2024

Seaweed extract shows promise in protecting neurons in Parkinson’s disease

Ecklonia cava polyphenols (ECPs) show promise in reducing neuronal damage caused by rotenone in Parkinson’s disease (PD) by activating the Nrf2-ARE pathway, highlighting their potential as a neuroprotective treatment.

7 Aug 2024

Study finds aspirin reduces colon cancer risk, with benefits varying by lifestyle factors

Aspirin can reduce colorectal cancer risk, but its effectiveness varies based on lifestyle factors such as diet, BMI, and smoking. Personalized recommendations are crucial to identify those who would benefit most from aspirin use.

7 Aug 2024

Small-town patients face big hurdles as rural hospitals cut cancer care

The night before her chemotherapy, Herlinda Sanchez sets out her clothes and checks that she has everything she needs: a blanket, medications, an iPad and chargers, a small Bible and rosary, fuzzy socks, and snacks for the road.

7 Aug 2024

The real cost of processed foods: How Western diets are harming global health

A recent study in Nature Medicine reviews the adverse effects of Western diets on human health, highlighting increased risks of chronic diseases and gut dysbiosis. Researchers call for global awareness and promotion of healthier dietary patterns.

6 Aug 2024

Menopause myths: Separating fact from fiction

Many women approach menopause with anxiety about the future. You've probably heard your grandmother, mother, or aunts lament about menopause, aka "the change," as a stressful time full of hot flashes, weight gain, and plummeting sex drive.

6 Aug 2024

Seaweed antioxidants show promise in preventing Parkinson's disease

Parkinson's disease is a neurodegenerative disease caused by the loss of neurons that produce dopamine, a neurotransmitter involved in motor control and cognitive function.

5 Aug 2024

The complex relationship between diet nutrition and cancer

The existing knowledge on the beneficial and detrimental effects of dietary patterns and nutritional supplements on cancer risk.

1 Aug 2024

New AI test may help bowel cancer patients avoid unnecessary chemotherapy

A new artificial intelligence (AI) test to determine the risk of bowel cancers coming back could help patients avoid chemotherapy, according to new research led by the University of Leeds.

31 Jul 2024

Exploring the role of diet and supplements in cancer prevention

Cancer is a complex, multifactorial disease with a substantial global burden. Recent years have seen a surge in research focusing on preventive measures, particularly through diet and supplements.

30 Jul 2024

New dual kinase inhibitor MTX-531 shows promise in overcoming cancer therapy resistance

A team of researchers at the University of Michigan Health Rogel Cancer Center has designed a molecule that impairs signaling mediated by two key drivers of cancer therapy resistance.

29 Jul 2024

Researchers find the effect of pesticides on increased cancer risk is comparable to smoking for some cancers

Researchers comprehensively evaluated the impact of pesticide use on cancer development in the United States.

29 Jul 2024

New biomarker helps determine the optimal treatment for colon cancer

Many people with stage II or III colon cancer receive additional, or adjuvant, chemotherapy following surgery. However, clinical trials have shown that this treatment doesn't improve the chances of survival for every patient. A study published July 25th, 2024 in Cell Reports Medicine identifies and validates a 10-gene biomarker that potentially predicts whether a stage II or III colon cancer patient will benefit from adjuvant chemotherapy.

27 Jul 2024

Noninvasive home test significantly cuts colorectal cancer mortality

A noninvasive colorectal cancer screening test that can be done at home could reduce the risk of colorectal cancer death by 33%, according to a new study published in JAMA Network Open.

25 Jul 2024

Reducing testing disparities could dramatically cut colon cancer rates among Black Americans

A new paper in the Journal of the National Cancer Institute, published by Oxford University Press, finds that eliminating the race disparity in colon cancer testing in the United States would reduce colon cancer, and colon cancer death rates, dramatically among Black people.

24 Jul 2024