Colorectal News and Research

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Two new projects aim to improve health care access for underserved populations

Nansi Boghossian and Melissa Nolan, both associate professors in the Arnold School's Department of Epidemiology and Biostatistics, have been awarded more than $600K each from The Duke Endowment to lead projects that improve access to health care for underserved populations.

25 Aug 2023

The role played by the gut microbiome in metabolizing selected sweeteners

The current evidence on the role of the gut microbiome in metabolizing sweeteners and their metabolites.

24 Aug 2023

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

23 Aug 2023

First complete sequences of multiple human Y chromosomes shed light on its evolution and biology

Highly challenging to sequence and long overlooked, the human Y chromosome's contributions to health and disease remain largely unknown.

23 Aug 2023

EHR-embedded AI tool can identify patients at risk for esophageal and stomach cancer

In the United States and other western countries, a form of esophageal and stomach cancer has risen dramatically over the last five decades. Rates of esophageal adenocarcinoma, or EAC, and gastric cardia adenocarcinoma, or GCA, are both highly fatal.

22 Aug 2023

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

The prevalence of colorectal cancer in people under the age of 50 has risen in recent decades. One suspected reason: the increasing rate of obesity and high-fat diets.

22 Aug 2023

Associations between alcohol intake, cancer risk, and modifying factors in women: smoking, BMI, and MHT interactions

Researchers examined the association between moderate alcohol intake and specific cancer risks.

21 Aug 2023

Can your screen time affect your bowel movements?

The causal relationship between leisure screen time and irritable bowel syndrome.

18 Aug 2023

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Patients with pancreatic cancer who took the benzodiazepine lorazepam (Ativan), commonly prescribed to treat anxiety during cancer treatment, had a shorter progression-free survival than patients who did not, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

17 Aug 2023

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have been awarded a grant from the U.S. Department of Defense (DoD)'s Congressionally Directed Medical Research Program to target chemotherapy resistance in pancreatic cancer.

17 Aug 2023

Can machine learning algorithms identify patients at risk of a delay in starting cancer treatment?

Multi-level machine learning models for estimating the risk of delay between cancer diagnosis and treatment initiation in a large group of cancer patients.

17 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

Epigenetic drug-sensitive biomarkers for cancer

Researchers perform an epigenome-wide multi-omic high-throughput screen to identify actionable epigenetic drug-sensitive biomarkers.

15 Aug 2023

Scientists identify key proteins driving cancer across multiple tumor types

Scientists have completed a deep analysis of the proteins driving cancer across multiple tumor types, information that can't be assessed by genome sequencing alone.

14 Aug 2023

CORRECTION: Air pollution linked to increased risk of non-lung cancers in older adults

Chronic exposure to fine particulate air pollutants (PM2.5) and nitrogen dioxide (NO2) may increase non-lung cancer risk in older adults, according to a study led by Harvard T.H. Chan School of Public Health.

11 Aug 2023

Gut microbiota could affect the responsiveness and efficacy of cancer treatment

A vast number of microbes colonizes the human body to form an ecological community known as the microbiota. Microbiota are made up of bacteria, viruses, fungi, and archaea.

11 Aug 2023

Study explores the use of existing medicines to revolutionize cancer treatment

In a recent study published in the journal of Genes & Diseases, Research team led by Lu explores the potential for the use of FDA-approved hypertension and EMA-approved cough medicines to revolutionize cancer treatment.

10 Aug 2023

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

Recently published preclinical data by City of Hope scientists shows the immunotherapy is effective. Advanced ovarian cancer patients are now being enrolled in a Phase 1 first-in-human trial.

10 Aug 2023

Study explores the diverse expression patterns of T cell priming markers across cancers

A recent study explored transcriptomics of T-cell priming markers (TPMs) across different cancers.

10 Aug 2023

Are inflammatory bowel disease patients more at risk of colorectal cancer?

Researchers analyzed data from a large cohort of inflammatory bowel disease patients and looked at the risk and frequency of colorectal cancer.

9 Aug 2023

Colorectal News and Research

Two new projects aim to improve health care access for underserved populations

The role played by the gut microbiome in metabolizing selected sweeteners

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

First complete sequences of multiple human Y chromosomes shed light on its evolution and biology

EHR-embedded AI tool can identify patients at risk for esophageal and stomach cancer

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

Associations between alcohol intake, cancer risk, and modifying factors in women: smoking, BMI, and MHT interactions

Can your screen time affect your bowel movements?

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

Can machine learning algorithms identify patients at risk of a delay in starting cancer treatment?

Genetic determinants of retinol circulation and their impact on health

Epigenetic drug-sensitive biomarkers for cancer

Scientists identify key proteins driving cancer across multiple tumor types

CORRECTION: Air pollution linked to increased risk of non-lung cancers in older adults

Gut microbiota could affect the responsiveness and efficacy of cancer treatment

Study explores the use of existing medicines to revolutionize cancer treatment

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

Study explores the diverse expression patterns of T cell priming markers across cancers

Are inflammatory bowel disease patients more at risk of colorectal cancer?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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