Colorectal News and Research

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Virtual colonoscopy raises issues for further study

The American Society for Gastrointestinal Endoscopy (ASGE) has reacted with caution to claims of the benefits of computed tomography (CT) colonography, also referred to as virtual colonoscopy, compared to standard colonoscopy.

29 Nov 2004

Cyclooxygenase (COX) inhibitors tested in both prevention and treatment clinical trials

Numerous compounds are examined by the National Cancer Institute (NCI) for their potential to prevent or treat cancer. One class of compounds, cyclooxygenase (COX) inhibitors, is currently being tested in both prevention and treatment clinical trials.

4 Nov 2004

Obese women at greater risk of colorectal cancer

New study findings show a high body mass index (BMI) among women is a more significant risk factor for colorectal neoplasia than for men.

1 Nov 2004

Smokers face a significant risk of developing colon polyps

Smokers can add pre-cancerous growths in the colon to the host of increased health risks they face, according to two studies presented at the 69th Annual Scientific Meeting of the American College of Gastroenterology.

1 Nov 2004

Scientists have found that a protein present in normal body tissues can prevent tumour growth

A team led by Dr Dave Bates, British Heart Foundation Lecturer, and Dr Steve Harper, Senior Research Fellow in the Microvascular Research Laboratories, in the Department of Physiology at Bristol University, have discovered that a type of vascular endothelial growth factor (VEGF) found in normal tissue, including blood, can prevent cancers from growing.

1 Nov 2004

Is NICE delivering the goods?

Implementation of guidance issued by the National Institute for Clinical Excellence (NICE) has been mixed, according to a study in this week's BMJ.

29 Oct 2004

Potential new treatment strategy against metastatic cancer cells

A team of scientists at The Scripps Research Institute has identified a potential treatment strategy against metastatic cancer cells that has never been tried before.

25 Oct 2004

Allopurinol, a common gout drug may also offer some protection against colorectal cancer

A commonly prescribed drug used to treat gout may also offer some protection against colorectal cancer, according to a new study from researchers at the University of Michigan and in Israel.

25 Oct 2004

New help to explain treatments for colorectal cancer

To help patients and their families better understand how different treatments work to cure colorectal cancer, the American Society for Therapeutic Radiology and Oncology has published the new patient information brochure Radiation Therapy for Colorectal Cancer: Facts to Help People Understand Their Treatment Options.

25 Oct 2004

Women and Hispanics are less likely to undergo colorectal cancer screening

Women and Hispanics are less likely to undergo colorectal cancer (CRC) screening but improving their access to CRC screening may be as simple as educating doctors to make the recommendation and explain its impact to patients, according to a new study.

25 Oct 2004

Researchers have uncovered a specific signaling mechanism that contributes to the development of colorectal cancer

The discovery furthers the understanding of mechanisms that contribute to disease progression and provides new avenues for development of therapies for colorectal cancer.

21 Oct 2004

Aspirin might well be considered the top utility player in the medicine cabinet

This cheap over-the-counter drug can be used not only for fever, pain and arthritis, but to prevent heart attack, stroke or angina. It also may reduce the risk of colorectal cancer. Yet aspirin also has side effects worth considering, and its very accessibility may hamper its use.

8 Oct 2004

$10 million to establish a multidisciplinary research program in cancer nanotechnology

The National Institutes of Health (NIH) has awarded scientists from Emory University and the Georgia Institute of Technology two new collaborative research grants, totaling nearly $10 million, to establish a multidisciplinary research program in cancer nanotechnology and to develop a new class of nanoparticles for molecular and cellular imaging.

6 Oct 2004

Immediate voluntary world-wide withdrawal of Vioxx (rofecoxib)

Pharmaceutical company, Merck Sharp & Dohme has announced an immediate voluntary world-wide withdrawal of the drug, Vioxx (rofecoxib), commonly used for patients with rheumatoid or osteoarthritis.

4 Oct 2004

Data demonstrate that Celebrex does not increase the risk of heart attack or stroke in patients with arthritis and pain

Pfizer has said that three large long-term Celebrex (celecoxib capsules) studies involving more than 6,000 patients have not shown any significant safety issues and are expected to continue to completion.

4 Oct 2004

Acne-like rash linked to effectiveness of new targeted cancer treatment – cetuximab

Acne is not a condition that anyone would welcome under normal circumstances, but an international study of a new targeted cancer treatment – cetuximab – has shown that patients who developed an acne-like rash responded better to the treatment than those who did not.

30 Sep 2004

Vitamin supplements not effective in protecting against gastro-intestinal cancer

A systematic review and meta-analysis (pooled analysis) of previously published randomised trials in this week’s issue of THE LANCET provides strong evidence that antioxidant supplements (such as vitamin supplements) are not effective in protecting against gastro-intestinal cancer.

30 Sep 2004

Even health conscious Americans report low rates of endoscopic screening for colorectal cancer

The study found just over half (54 percent) of men and women reported having ever undergone endoscopy (sigmoidoscopy or colonoscopy). The percentage that underwent either procedure in the past five years for screening rather than for disease diagnosis or follow up was just 24 percent.

30 Sep 2004

FDA to highlight benefits and risks of hormone therapy for menopausal symptoms

The Food and Drug Administration (FDA) is implementing a nationwide information campaign to raise awareness about the resources available to address questions related to the benefits and risks of hormone therapy for menopausal symptoms.

29 Sep 2004

Newly completed Chromosome 5 sequence will be a powerful tool for scientists trying to understand human disease

Four years after publicly revealing the official draft human genetic sequence, researchers have reached the halfway point in dotting the i's and crossing the t's of the genetic sentences describing how to build a human.

16 Sep 2004

Colorectal News and Research

Virtual colonoscopy raises issues for further study

Cyclooxygenase (COX) inhibitors tested in both prevention and treatment clinical trials

Obese women at greater risk of colorectal cancer

Smokers face a significant risk of developing colon polyps

Scientists have found that a protein present in normal body tissues can prevent tumour growth

Is NICE delivering the goods?

Potential new treatment strategy against metastatic cancer cells

Allopurinol, a common gout drug may also offer some protection against colorectal cancer

New help to explain treatments for colorectal cancer

Women and Hispanics are less likely to undergo colorectal cancer screening

Researchers have uncovered a specific signaling mechanism that contributes to the development of colorectal cancer

Aspirin might well be considered the top utility player in the medicine cabinet

$10 million to establish a multidisciplinary research program in cancer nanotechnology

Immediate voluntary world-wide withdrawal of Vioxx (rofecoxib)

Data demonstrate that Celebrex does not increase the risk of heart attack or stroke in patients with arthritis and pain

Acne-like rash linked to effectiveness of new targeted cancer treatment – cetuximab

Vitamin supplements not effective in protecting against gastro-intestinal cancer

Even health conscious Americans report low rates of endoscopic screening for colorectal cancer

FDA to highlight benefits and risks of hormone therapy for menopausal symptoms

Newly completed Chromosome 5 sequence will be a powerful tool for scientists trying to understand human disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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