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FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

The U.S. Food and Drug Administration today approved Ogivri (trastuzumab-dkst) as a biosimilar to Herceptin (trastuzumab) for the treatment of patients with breast or metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma) whose tumors overexpress the HER2 gene (HER2+).

4 Dec 2017

Study provides insight into adaptive evolution of common cold viruses

Common cold season is back, which has people wondering why we catch the same virus, year after year. Why don't we ever develop immunity against the common cold? Professor Pierre Talbot at INRS has known about the incredible variability of coronaviruses for some time.

28 Nov 2017

4-in-1 influenza vaccine appears to provide broad protection against flu

A vaccine combining centralized ancestral genes from four major influenza strains appears to provide broad protection against the dangerous ailment, according to new research by a team from the Nebraska Center for Virology.

3 Nov 2017

New smell test could help improve early diagnosis of Alzheimer's, Parkinson's diseases

Nisha Pradhan was seven when she began to suspect she was missing out on something. Her sister seemed to have an uncanny knack for predicting what their mother was making for dinner. Pradhan, meanwhile, never had a clue.

11 Oct 2017

New test for meningitis could speed up diagnosis and save lives

Clinicians at an A&E department in Northern Ireland are to start using a new test that rapidly detects meningitis, potentially speeding up diagnosis and saving lives.

30 Aug 2017

Air pollution particles could make you more susceptible to infection, say scientists

AIR pollution could make you more vulnerable to infection, scientists at a Scots university have revealed.

18 Aug 2017

Tiny molecule in the immune system could help develop cure for common cold

A tiny molecule found in the immune systems of humans and animals could be used to develop a cure for the common cold, new research suggests.

3 Aug 2017

Researchers unlock better treatment strategy for viral diseases

RMIT University scientists in Melbourne, Australia, have led an international collaboration that potentially unlocks better treatment of viral diseases, including the flu and common cold.

12 Jul 2017

Antibiotic use during peripartum period linked to greater risk of inflammatory condition in offspring

A study by researchers at the University of Chicago Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles human IBD.

11 Jul 2017

FDA expands approval for cystic fibrosis drug to treat additional rare gene mutations

The U.S. Food and Drug Administration today expanded the approved use of Kalydeco (ivacaftor) for treating cystic fibrosis.

18 May 2017

Experimental gene therapy proven safe for preserving vision of people with AMD

In a small and preliminary clinical trial, Johns Hopkins researchers and their collaborators have shown that an experimental gene therapy that uses viruses to introduce a therapeutic gene into the eye is safe and that it may be effective in preserving the vision of people with wet age-related macular degeneration.

17 May 2017

Zinc acetate lozenges may provide 3-fold increase in recovery rate from common cold

According to a meta-analysis of three randomized controlled trials published in Open Forum Infectious Diseases, zinc acetate lozenges may increase the rate of recovery from the common cold three fold. On the fifth day, 70% of the zinc lozenge patients had recovered compared with 27% of the placebo patients.

11 May 2017

Study finds high rate of unnecessary antibiotic prescribing for low-risk Ontarian seniors

Nearly one in two seniors in Ontario who visited a family doctor for a non-bacterial infection received an unnecessary antibiotic prescription, according to a new study from the Institute for Clinical Evaluative Sciences Western site in London, Ontario and Lawson Health Research Institute.

9 May 2017

Zinc acetate and zinc gluconate lozenges show similar efficacy in shortening duration of common colds

There is no significant difference between zinc acetate lozenges and zinc gluconate lozenges regarding their efficacy in shortening the duration of common colds according to a meta-analysis published in Journal of the Royal Society of Medicine Open.

3 May 2017

Researchers use gene-editing tool to restore visual function in mouse models of retinitis pigmentosa

Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, with colleagues in China, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of retinitis pigmentosa.

21 Apr 2017

TSRI scientists find new way to make cell population resistant to HIV

Scientists at The Scripps Research Institute have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus.

11 Apr 2017

Study finds unnecessary referrals, testing in patients treated at hospital-based primary practices

Patients with common conditions such as back pain, headaches and upper respiratory infections are more likely to receive tests and services of uncertain or little diagnostic or therapeutic benefit--so-called low-value care--when they seek treatment in primary care clinics located at hospitals rather than at community-based primary care clinics, according to a nationwide study led by researchers at Harvard Medical School and the David Geffen School of Medicine at UCLA.

10 Apr 2017