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NicOx updates on PF-03187207 and research collaboration with Pfizer

NicOx S.A. has announced the results of a dose-ranging phase 2 study conducted with PF‑03187207 in Japanese patients with glaucoma by its partner Pfizer Inc. PF-03187207 is a nitric oxide-donating prostaglandin analog. The study was designed to compare the safety and efficacy of several doses of PF-03187207 to Xalatan (latanoprost) and enrolled 112 Japanese patients with primary open-angle glaucoma or ocular hypertension.

25 Aug 2008

Intel's CTO says technology will bring man and machine much closer together by 2050

Intel Corporation's chief technology officer took a fascinating look at how technology will bring man and machine much closer together by 2050.

21 Aug 2008

Scientists uncover molecule that keeps pathogens like salmonella in check

Scientists at UT Southwestern Medical Center have found a potential new way to stop the bacteria that cause gastroenteritis, tularemia and severe diarrhea from making people sick.

21 Aug 2008

Codeine use may be risky for some breastfeeding mothers

Using pain treatments which contain codeine may be risky for some breastfeeding mothers, according to researchers at The University of Western Ontario, and the Hospital for Sick Children (SickKids) in Toronto.

20 Aug 2008

One night without sleep increases chemical dopamine in the human brain

Because drugs that increase dopamine, like amphetamines, promote wakefulness, the findings offer a potential mechanism explaining how the brain helps people stay awake despite the urge to sleep. However, the study also shows that the increase in dopamine cannot compensate for the cognitive deficits caused by sleep deprivation.

19 Aug 2008

Stanford develop method to overcome multiple drug resistant diseases

Many drugs once considered Charles Atlases of the pharmaceutical realm have been reduced to the therapeutic equivalent of 97-pound weaklings as the diseases they once dispatched with ease have developed resistance to them.

18 Aug 2008

Mosquitoes smell DEET and stay away

Spray yourself with a DEET-based insect repellent and the mosquitoes will leave you alone. But why? They flee because of their intense dislike for the smell of the chemical repellent and not because DEET jams their sense of smell, report researchers at the University of California, Davis.

18 Aug 2008

Spice-based compound to fight against cancer

Seeking to improve on nature, scientists used a spice-based compound as a starting point and developed synthetic molecules that, in lab settings, are able to kill cancer cells and stop the cells from spreading.

17 Aug 2008

Diakron licenses anticoagulant drug candidate from Merck

Diakron Pharmaceuticals, Inc. announced today the signing of an exclusive license agreement for a novel investigational oral anticoagulant drug candidate discovered and developed through Phase I clinical trials by Merck & Co. Inc. Under the terms of the agreement, Diakron has the exclusive rights to develop, and, if approved, market and distribute the compound worldwide.

13 Aug 2008

NanoBio vaccine for hepatitis B shows promise

Chronic hepatitis B infects 400 million people worldwide, many of them children. Even with three effective vaccines available, hepatitis B remains a stubborn, unrelenting health problem, especially in Africa and other developing areas. The disease and its complications cause an estimated 1 million deaths globally each year.

13 Aug 2008

Oxygen Biotherapeutics develops gel version of Oxycyte for treating surface wounds

Oxygen Biotherapeutics, Inc. has announced that the company has developed a gel-like form of Oxycyte that it intends to investigate as a topical application for open wounds, abrasions and burns. Oxycyte is the Company's perfluorocarbon (PFC) therapeutic oxygen carrier.

12 Aug 2008

PET scans spot signs of early Alzheimer's

Scientists in Finland say a type of imaging technique known as positron emission tomography (PET) scanning may be a useful and non-invasive way of diagnosing the early stages of Alzheimer’s disease.

11 Aug 2008

Viread approved for chronic hepatitis B

The FDA has approved Viread (tenofovir disoproxil fumarate) as a treatment option for adults with chronic hepatitis B, a serious liver disease.

11 Aug 2008

Researchers find a cancer-inhibiting cyanobacteria that grows on coral reefs

University of Florida College of Pharmacy researchers have discovered a marine compound off the coast of Key Largo that inhibits cancer cell growth in laboratory tests, a finding they hope will fuel the development of new drugs to better battle the disease.

10 Aug 2008

New understanding on how Chilli peppers increase metabolism and body temperature

Chilli peppers can do more than just make you feel hot, reports a study in the August 1 Journal of Biological Chemistry; the active chemical in peppers can directly induce thermogenesis, the process by which cells convert energy into heat.

6 Aug 2008

Medicinal cannabis effective for neuropathic pain in HIV

In a double-blind, placebo-controlled clinical trial to assess the impact of smoked medical cannabis, or marijuana, on the neuropathic pain associated with HIV, researchers at the University of California, San Diego School of Medicine found that reported pain relief was greater with cannabis than with a placebo.

6 Aug 2008

Discovery of vital key to cancer

University of Manchester scientists have uncovered the 3D structure of Mps1 - a protein that regulates the number of chromosomes during cell division and thus has an essential role in the prevention of cancer - which will lead to the design of safer and more effective therapies.

From The University of Manchester 6 Aug 2008

Maggots the key to fighting superbugs

Scientists at Swansea University in Wales have discovered that maggots may hold the key to fighting superbugs.

5 Aug 2008

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer

CB1 is well-established for relieving pain and nausea, elevating mood and stimulating appetite by serving as a docking station for the cannabinoid group of signaling molecules. It now may serve as a new path for cancer prevention or treatment.

3 Aug 2008

Some bacteria steal iron from their human hosts - discovery could lead to new ways to fight tuberculosis

Like their human hosts, bacteria need iron to survive and they must obtain that iron from the environment. While humans obtain iron primarily through the food they eat, bacteria have evolved complex and diverse mechanisms to allow them access to iron.

31 Jul 2008