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Old drug pentylenetetrazole may improve learning and memory in Down syndrome victims

Researchers in the United States have discovered that an old drug once used to study epilepsy substantially improved learning and memory in mice with Down syndrome symptoms.

26 Feb 2007

Injections with "dermal fillers" containing hyaluronic acid may partially restore sun-damaged skin

Injectable skin fillers have become increasingly popular for correcting the lines and wrinkles associated with aging, as well as acne scars and other skin conditions, according to background information in the article.

20 Feb 2007

Procalcitonin helps predict prognosis among those with peritonitis

Monitoring blood levels of a compound known as procalcitonin in patients with peritonitis (a serious intra-abdominal infection) could help identify patients at increased risk of organ failure and death, according to a report in the February issue of Archives of Surgery.

20 Feb 2007

HIV protein TAT used to pull protein Bim into cancer cells - helps kill cancer cells

Cancer cells are sick, but they keep growing because they don't react to internal signals urging them to die. Now researchers at Washington University School of Medicine in St. Louis have found an efficient way to get a messenger into cancer cells that forces them to respond to death signals. And they did it using one of the most sinister pathogens around - HIV.

15 Feb 2007

Maraviroc to receive accelerated review in U.S. and Europe

Pfizer announced today that marketing authorization applications for maraviroc will receive accelerated review in both the United States and Europe. Accelerated reviews are granted to potential medicines that, if approved, would represent significant improvements over current therapies.

13 Feb 2007

Researchers discover how to fight iron disorders with a drug against hypertension

We all know that iron deficiencies are dangerous, but also too much iron is bad for our health. Our body stores excess iron in various tissues, where it can lead to organ failure and even death if not treated before irreversible damage has occurred.

12 Feb 2007

Natural gum improves gold nanoparticles for cancer imaging

Gold nanoparticles have shown significant promise as agents to detect and treat cancer, but researchers have had difficulty creating gold nanoparticles that have suitable pharmacological properties for use in humans.

12 Feb 2007

New, rapid-detection system for Salmonella

The food and drink we consume have to pass strict quality controls. Nevertheless, these measures are not always sufficient, given that sometimes certain foodstuffs can still give rise to food poisoning, most often caused by micro-organisms. The Salmonella bacterium is undoubtedly one of the best known of these.

8 Feb 2007

Sniff of male sweat kick starts female hormones

According to a new study all a healthy heterosexual woman needs to give their hormone levels a kick start is the smell of a man's sweat.

8 Feb 2007

ViroPharma receives orphan drug designation for Maribavir

ViroPharma Incorporated today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for maribavir for prevention of cytomegalovirus (CMV) viremia and disease in the populations at-risk.

7 Feb 2007

Bright quantum dots help basic cancer biology studies

Though there is little doubt that nanoscale devices are going to play a critical role in improving cancer detection and treatment over the next five to ten years, nanoparticles are already having a major impact on the way that cancer biologists study the processes that go awry within malignant and metastatic cells.

5 Feb 2007

Antipodean Pharma commences phase 2 trial in hepatitis C

Antipodean Pharmaceuticals has announced it has initiated a Phase 2 clinical trial of its lead compound MitoQ (mitoquinone) to investigate the drug's efficacy to reduce liver damage in patients with raised liver enzymes associated with the Hepatitis C virus (HCV).

5 Feb 2007

Cancer Research Technology grants Waypharm option to novel platinum agents

Cancer Research Technology Limited (CRT), the cancer-focused development and commercialisation company, today announce that Waypharm S.A.S (Waypharm) has secured rights to evaluate Thioplatin a novel hypoxia-responsive platinum-based cancer therapy, from CRT.

5 Feb 2007

Potential new cancer fighting drug found by mistake

Researchers in the United States appear to have almost inadvertently stumbled across what could be a new cancer treatment.

5 Feb 2007

Cellulose sulfate microbicide stopped

A Phase III study of the candidate microbicide cellulose sulfate to prevent HIV transmission in women has been stopped prematurely because of a higher number of HIV infections in the active compared with the placebo group.

31 Jan 2007

FDA approves Neuren's phase 3 Glypromate trial

Neuren Pharmaceuticals has announced that the US Food and Drug Administration (FDA) has accepted its investigational new drug application (IND) and authorised the Company to proceed with its Phase 3 trial to prevent cognitive impairment following major cardiac surgery using Glypromate.

30 Jan 2007

Nventa Bio issued U.S patent for heat shock protein fusion to treat influenza

The patent provides coverage for compositions of fusion proteins comprised of an influenza antigen fused to a heat shock protein (Hsp), as well as DNA encoding such fusion proteins and their use in immunotherapy.

30 Jan 2007

Access Pharmaceuticals issued U.S. patent

This patent, entitled "O,O'-Amidomalonato and N,O-Amidomalonato Platinum Complexes" is one of a series of patents and patent applications owned by Access which provides intellectual property protection to ProLindac and related tumor-targeted platinum compounds.

30 Jan 2007

Probing proteins can lead to better understanding of anti-tumor agents

There are a number of naturally occurring chemicals that are used in phototherapy of skin diseases. Hypocrellin A (HA), which can be extracted from a parasitic fungus, has been taken orally as a folk medicine for several centuries in China.

29 Jan 2007

Small molecule targets weak mRNA

A new strategy for fighting cancer aims to make its genes get lost in translation, according to a report in the January 26, 2007, issue of the journal Cell.

28 Jan 2007