Confocal microscopy News and Research

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Researchers unravel the mechanism of teixobactin at the atomic level

Researchers explored the mechanisms underlying the bactericidal action of teixobactin at an atomic level.

8 Aug 2022

Tunneling nanotubes can assist SARS-CoV-2 propagation

A new study found that tunneling nanotubes (TNTs) offer a pathway for SARS-CoV-2 neuronal spreading.

26 Jul 2022

UMass Amherst scientist to study how embryonic exposure to pollutants may increase diabetes risk

A University of Massachusetts Amherst environmental health scientist has received a $2.44 million, five-year grant renewal from the National Institutes of Health to continue her research into how embryonic exposure to certain common pollutants may put people at risk for diabetes and other metabolic health conditions later in life.

22 Jul 2022

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A recent study by scientists at Celentyx Ltd, the University of Birmingham, and the University of Warwick and posted to the bioRxiv* preprint server illustrated a cell-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein attachment assay.

28 Jun 2022

Research may open door to the design of a better structured rabies vaccine

Rabies virus kills a shocking 59,000 people each year, many of them children. Some victims, especially kids, don't realize they've been exposed until it is too late.

17 Jun 2022

Molecular snapshots of the productive infectious entry pathway of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States demonstrated that the acidic milieu of the nasal cavity is critical for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tropism.

14 Jun 2022

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have identified a new metabolic mechanism in liver cancer cells, by which macropinocytosis, an endocytic process, is used to engulf extracellular proteins as fuels to support the unlimited growth of hepatocellular carcinoma (HCC) in hypoxia (oxygen deprivation).

14 Jun 2022

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

Researchers have successfully treated type 1 diabetes in mice using pancreatic beta-cell, target-specific, chimeric antigen-receptor (CAR) regulatory T cells (Tregs), and demonstrated the feasibility of their approach to treat the human condition according to data being presented Monday, June 13 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Researchers observed SARS-CoV-2 downregulates the expression of MHC class I molecules.

23 May 2022

Insight into sustained-release drug delivery systems

In this interview, News-Medical speaks to Thanh T. Nguyen, a project manager at Innocore Pharmaceuticals, about the mechanisms behind long-acting injectables.

From Thermo Fisher Scientific – Materials Characterization 18 May 2022

Why do diabetic patients have more severe SARS-CoV-2 infections?

A recent study published in the journal Cell Metabolism illustrated the function of angiotensin-converting enzyme 2 (ACE2) in renal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among diabetic patients.

16 May 2022

Targeting specific neurons modulates memory retrieval and alters anxiety-like behaviors in mice

We humans lose mental acuity, an unfortunate side effect of aging. And for individuals with neurodegenerative conditions such as Alzheimer's and Parkinson's, the loss of cognitive function often accompanied by mood disorders such as anxiety is a harrowing experience.

16 May 2022

Confocal microscopy News and Research

Researchers unravel the mechanism of teixobactin at the atomic level

Tunneling nanotubes can assist SARS-CoV-2 propagation

UMass Amherst scientist to study how embryonic exposure to pollutants may increase diabetes risk

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

Research may open door to the design of a better structured rabies vaccine

Molecular snapshots of the productive infectious entry pathway of SARS-CoV-2 into cells

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Insight into sustained-release drug delivery systems

Why do diabetic patients have more severe SARS-CoV-2 infections?

Targeting specific neurons modulates memory retrieval and alters anxiety-like behaviors in mice

Microbes can influence which of the gut's genes are being called into action

Discovery of host co-factors necessary for SARS-CoV2 infection

Researchers develop a live imaging system to observe collagen synthesis

The molecular context and substrate profiles of human cell surface receptor tyrosine kinases

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Masks made of woven fabrics are lousy air filters

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

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