Coronary Artery Bypass Surgery News and Research

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Coronary Artery Bypass is surgery in which a healthy blood vessel taken from another part of the body is used to make a new path for blood around a blocked artery leading to the heart. This restores the flow of oxygen and nutrients to the heart. Also called aortocoronary bypass and CAB.

Life after coronary bypass surgery

For many years, assumptions have lingered that Coronary Artery Bypass Surgery Grafting (CABG) produces measurable cognitive impairment, either because of the surgery or use of cardiopulmonary bypass.

4 Apr 2008

Drug does not appear to reduce risk of heart attack or death following CABG surgery

Use of MC-1 (a naturally occurring metabolite of vitamin B6) before and for 30 days after coronary artery bypass graft surgery did not reduce the risk of heart attack or cardiovascular death, according to a JAMA study being released early online April 1 to coincide with its presentation at the annual conference of the American College of Cardiology.

2 Apr 2008

Study confirms aprotinin drug increases cardiac surgery death rate

The largest study to date of a controversial cardiac surgery drug shows it increases death rates and damages kidney function, according Duke University Medical Center researchers.

21 Feb 2008

Daiichi Sankyo, Lilly submit NDA for investigational antiplatelet drug, Prasugrelin U.S.

Daiichi Sankyo Company, Limited and Eli Lilly and Company have announced that on Wednesday, Dec. 26, 2007, they submitted a New Drug Application (NDA) for prasugrel to the U.S. Food and Drug Administration (FDA).

7 Jan 2008

FDA committees recommend continued U.S. marketing for Trasylol

The Cardiovascular and Renal Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee to the U.S. Food and Drug Administration (FDA) held a meeting to discuss the risk /benefit profile of Trasylol (aprotinin injection), a Bayer drug used in coronary artery bypass graft (CABG) surgery.

13 Sep 2007

How to optimally prepare a patient for planned coronary angiography and subsequent angioplasty?

A Czech study compared two anti-clotting treatment regimens, currently used before coronary angiography / angioplasty to find the optimal balance between preventing ischemic versus bleeding complications of these procedures. The study was conducted in five Czech tertiary cardiology centers.

3 Sep 2007

Restricting the blood flow to the arm may improve outcomes of heart surgery

A new study suggests that patients undergoing coronary artery bypass surgery may have improved outcomes by having a procedure done that temporarily restricts the blood flow in their arm.

20 Aug 2007

Schering-Plough announces licensing of Acadesine

Schering-Plough Corporation has announced the worldwide licensing of acadesine, an investigational, potentially first-in-class adenosine regulating agent (ARA), from PeriCor Therapeutics, Inc., a privately held, specialty biopharmaceutical company.

20 Jul 2007

Cardiac surgery in patients with liver cirrhosis

A new study on the outcome of cardiac surgery in patients with liver cirrhosis found that the surgery can safely be performed in patients with milder disease, while those with more severe cirrhosis are less likely to survive.

4 Jul 2007

Newer breast cancer drug may protect heart

By uncovering how one breast cancer drug protects the heart and another does not, Duke University Medical Center researchers believe they may have opened up a new way to screen drugs for possible heart-related side effects and to develop new drugs.

16 Jun 2007

Simple test predicts a person's risk for developing dementia within six years with 87 percent accuracy

The test, developed in the study by the researchers, is a 14-point index combining medical history, cognitive testing, and physical examination. It requires no special equipment and can be given in a clinical setting such as a doctor's office or at a patient's bedside.

16 Jun 2007

Blood pressure drop during bypass surgery linked to increased risk of cognitive decline

Patients whose mean arterial blood pressure drops during bypass surgery may be at risk for early difficulties in thinking, learning and memory, according to an article posted online today that will appear in the August 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.

14 Jun 2007

Researchers shed light on the link between chronic inflammation and atherosclerosis

Rheumatoid arthritis, lupus, and other inflammatory rheumatic diseases are associated with a high rate of death from heart disease.

28 May 2007

Role of PCI and coronary artery bypass grafting for the treatment of patients with left main coronary artery disease

Coronary artery bypass surgery has been the preferred treatment for patients with a blockage in the left main coronary artery, the conduit that supplies blood to about two-thirds of the heart.

15 May 2007

Variants of two genes involved in the inflammatory system linked to cognitive decline after heart surgery

Duke University Medical Center researchers believe their findings could help physicians identify patients at risk of suffering mental decline after heart surgery and raises the possibility that these patients could be treated with drugs that are known to dampen the inflammatory response.

2 May 2007

Performance league tables are linked to lower death rates after major heart surgery

The findings are based on almost 26,000 patients who had coronary artery bypass surgery (CABG) for the first time between1997 to 2005, in the north west of England.

25 Apr 2007

Corticosteroids after cardiac surgery lower risk of atrial fibrillation

Patients who receive corticosteroids after cardiac surgery have a significantly lower risk of atrial fibrillation in the days following the surgery, according to a study in the April 11 issue of JAMA.

11 Apr 2007

Plavix appears to be safe during and after heart bypass

Heart surgeons don't have to choose between taking a coronary-bypass patient off the popular anti-clotting drug clopidogrel (Plavix) after off-pump heart bypass surgery or having the patient bleed excessively in the days following surgery, according to a new study by researchers at Jefferson Medical College.

28 Mar 2007

Aprotinin use associated with an increased risk of death following CABG surgery

Aprotinin, a drug used for limiting blood loss in patients undergoing cardiac surgery, is associated with an increased risk of death during five years following the surgery, according to a new study in the February 7 issue of JAMA: The Journal of the American Medical Association.

7 Feb 2007

Incidence of kidney damage associated with coronary artery bypass surgery has increased significantly

The incidence of kidney damage associated with coronary artery bypass surgery has increased significantly over the past 16 years in the United States, but the rate of death from such damage has decreased significantly during the period, according to a new analysis.

16 Oct 2006