Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

Two uveitis drugs perform similarly in a head-to-head clinical trial

Methotrexate and the more expensive mycophenolate mofetil performed similarly in a head-to-head clinical trial that compared the two drugs for treating noninfectious uveitis, an eye disease that accounts for up to 15% of blindness in the U. S.

11 Sep 2019

Wild birds help shed light on stress resilience in humans

Stress is a common everyday experience, particularly in the world today. A new study might open the doors for the prevention and treatment of stress disorders, thanks to wild songbirds.

21 Jul 2019

$FDA grants accelerated approval to new treatment for refractory multiple myeloma$

FDA grants accelerated approval to new treatment for refractory multiple myeloma

Today, the U.S. Food and Drug Administration granted accelerated approval to Xpovio (selinexor) tablets in combination with the corticosteroid dexamethasone for the treatment of adult patients with relapsed refractory multiple myeloma who have received at least four prior therapies and whose disease is resistant to several other forms of treatment, including at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody.

3 Jul 2019

First treatment approved by FDA for chronic rhinosinusitis with nasal polyps

The U.S. Food and Drug Administration today approved Dupixent (dupilumab) to treat adults with nasal polyps (growths on the inner lining of the sinuses) accompanied by chronic rhinosinusitis (prolonged inflammation of the sinuses and nasal cavity).

26 Jun 2019

New intervention shows promise for relief of shoulder pain in wheelchair users with spinal cord injury

A New Jersey team of researchers has reported the successful, long-term relief of chronic refractory shoulder pain in a wheelchair user with spinal cord injury following a single injection of autologous, micro-fragmented adipose tissue into the affected shoulder joint.

12 Jun 2019

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens, the study's leaders announced this week.

6 Jun 2019

Dyson-Hudson receives grant to study effectiveness of new treatment for shoulder pain

Trevor Dyson-Hudson, MD, director of the Center for Spinal Cord Injury Research at Kessler Foundation, was awarded a $549,000 grant by the New Jersey Commission on Spinal Cord Research.

31 May 2019

Innovative treatment improves vision of a patient suffering from melanoma-associated retinopathy

Innovative treatment has improved the vision of a patient suffering from a rare cancer-related syndrome affecting the eye, new research in the journal JAMA Ophthalmol reports.

30 Apr 2019

Sweden shows greatest improvement in saving extremely preterm babies

The survival rate among extremely preterm babies has greatly improved in Sweden, a country that offers top-class neonatal care, a study led from Karolinska Institutet published in the esteemed journal JAMA reports.

27 Mar 2019

Drug that prevents respiratory ailments in preemies reduces healthcare costs

A new study from researchers at Columbia University Vagelos College of Physicians and Surgeons shows that a drug given to some pregnant women to prevent severe respiratory ailments in preterm newborns reduces healthcare costs.

14 Mar 2019

Exposure to antenatal corticosteroid therapy associated with reduced fetal growth

Infants exposed to antenatal corticosteroid therapy to accelerate lung maturation have a clinically significant reduction in birth size, according to a new of study of 278,508 births published this week in PLOS Medicine by Alina Rodriguez of the University of Lincoln and Imperial College London, UK, and colleagues.

28 Feb 2019

Preterm babies whose mother's received steroid treatment have lower birth weight

Steroid injections given to mothers at risk of giving birth prematurely are linked to babies being born with lower body weights.

26 Feb 2019

Machine learning technique helps predict which asthma patients respond to corticosteroid therapy

Physicians will be able to predict which of their patients with severe asthma are likely to benefit from treatment with systemic corticosteroids -- and which might only suffer their side effects -- with help from a dozen clinical variables researchers have identified using machine learning techniques.

20 Feb 2019

Fish oil does not appear to provide therapeutic benefits for obese teens with uncontrolled asthma

Fish oil does not appear to improve asthma control in adolescents and young adults with uncontrolled asthma who are overweight or obese, according to new research published online in the Annals of the American Thoracic Society.

25 Jan 2019

AGA's new clinical guideline to help manage patients with mild-to-moderate ulcerative colitis

Most patients with ulcerative colitis have mild-to-moderate disease characterized by periods of activity or remission, but practice variations exist in disease management.

10 Jan 2019

Potential combination therapy against rare disease of the bone marrow could improve treatment

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. Its low incidence rate is one of the reasons why effective therapies are still lacking.

19 Dec 2018

Pooled analysis of Intersect ENT's steroid releasing implants in patients after frontal sinus surgery to be published

Intersect ENT, Inc., a company dedicated to transforming care for patients with ear, nose and throat conditions, today announced publication of a pooled analysis in the International Forum of Allergy & Rhinology, the official journal of the American Rhinologic Society, of the company's PROPEL Contour and PROPEL Mini steroid-releasing sinus implants showing improved outcomes of frontal sinus surgery.

16 Nov 2018

How to avoid shoulder injury related to vaccine administration

A study by researchers at the University of Waterloo reiterates the need for health care professionals, including pharmacists, to take certain precautions to minimize the risk of their patients suffering shoulder injury related to vaccine administration

24 Oct 2018

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Genentech, a member of the Roche Group, today announced positive results from the Phase III IMpower130 study of Tecentriq (atezolizumab) plus chemotherapy (carboplatin and Abraxane® [albumin-bound paclitaxel; nab-paclitaxel]) for the initial (first-line) treatment of people with previously untreated metastatic non-squamous non-small cell lung cancer.

22 Oct 2018

Combination of Opdivo and Yervoy shows four-year survival benefits in patients with advanced melanoma

Bristol-Myers Squibb Company today announced four-year data from the Phase 3 CheckMate -067 clinical trial - the longest follow-up to date - which continues to demonstrate durable, long-term survival benefits with the first-line combination of Opdivo (nivolumab) and Yervoy (ipilimumab), versus Yervoy alone, in patients with advanced melanoma.