Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

Major bone trial to test high dose corticosteroid steroid tablets

Researchers in Aberdeen are about to launch a major multi-centre clinical trial to test whether a new drug could prevent bone thinning in adults taking moderate to high dose corticosteroid "steroid" tablets, such as prednisolone.

8 Nov 2004

Genes affect how asthma patients respond to albuterol

While a few weeks of regular use of albuterol improved overall asthma control in individuals with one form of the gene, stopping all use of albuterol eventually improved asthma control in those with another form of the gene. Albuterol is the most commonly used drug for relief of acute asthma symptoms, or “attacks.”

22 Oct 2004

Bactericidal (bacteria-killing) versus bacteriostatic (bacteria-inhibiting) drugs for treating infections

When treating an infection, physicians may face a choice between using a bactericidal (bacteria-killing) drug, a bacteriostatic (bacteria-inhibiting) drug or a combination of the two.

21 Oct 2004

Patients with stable vitiligo may achieve good repigmentation with skin transplants using skin taken from normally-pigmented areas of their own bodies

Patients with stable vitiligo, a skin disorder characterized by patches of lighter colored, or depigmented skin, may achieve good repigmentation of these areas with skin transplants using skin taken from normally-pigmented areas of their own bodies

18 Oct 2004

The use of anti-inflammatory drugs to treat severe head injuries is actually dangerous

The use of anti-inflammatory drugs to treat patients with severe head injuries—common practice worldwide for the past 30 years—is actually dangerous and associated with around a 20% increase in death within two weeks of hospital admission, conclude authors of an international study in this week’s issue of THE LANCET.

8 Oct 2004

Reducing eosinophilic airway inflammation in severe asthma

Eosinophils are a type of white blood cell that constitute from 1 to 3 percent of the total white cell count. When foreign substances or infectious cells enter the body, lymphocytes and neutrophils attract eosinophils which release toxic substances that can destroy abnormal cells. Eosinophils function in allergic responses and in helping resist some infections.

4 Oct 2004

Stress hormones lower threshold for aggression and aggression raises stress hormones

Scientists may be learning why it’s so hard to stop the cycle of violence. The answer may lie in the nervous system.

4 Oct 2004

A new lipid-based nasal ointment effective at reducing symptoms of allergic rhinitis

One in five Americans have allergic rhinitis, a number that is steadily rising, but the exact reasons for this increase are unknown. A new lipid-based nasal ointment is found effective at reducing symptoms of allergic rhinitis in German patients.

18 Sep 2004

Regulatory agency alerts consumers about poor quality of some traditional chinese medicines

The Medicines and Healthcare products Regulatory Agency (MHRA) has issued advice to consumers and the herbal sector about the poor quality of some traditional chinese medicines (TCMs) on the UK market.

5 Sep 2004

FDA approves revised labeling for anti-inflammatory corticosteroid nasal spray

AstraZeneca has announced that the U.S. Food and Drug Administration has approved revised labeling for its anti-inflammatory corticosteroid nasal spray RHINOCORT AQUA® (budesonide).

26 Aug 2004

Children who take steroid drugs for nephrotic syndrome do not suffer bone loss

Childhood nephrotic syndrome, which affects 3 out of 100,000 children, is the most common chronic kidney disease in children. Although it does not impair kidney function, it weakens the body's ability to remove water and salt from the blood, and causes swelling in the belly, legs, and around the eyes.

25 Aug 2004

Results from study of Rituxan in rheumatoid arthritis show promise

Genentech, Inc., Biogen Idec and Roche have announced that the New England Journal of Medicine published the results of a Phase IIa study showing that two doses of Rituxan® (Rituximab), administered two weeks apart, improved symptoms in patients with moderate-to-severe rheumatoid arthritis (RA) for up to 48 weeks when combined with methotrexate (MTX), compared to MTX alone.

16 Jun 2004

Pediatric asthma patients given a certain inhaled corticosteroid had a 29 percent lower risk of ending up in emergency

A study presented today at the 100th International Conference of the American Thoracic Society in Orlando shows pediatric asthma patients given a certain inhaled corticosteroid had a 29 percent lower risk of ending up in the emergency department (ED) or being admitted into the hospital.

25 May 2004

A new guideline evaluates the treatment of infantile spasms

A new guideline developed by the American Academy of Neurology and the Child Neurology Society evaluates the treatment of infantile spasms. The guideline is published in the May 25 issue of Neurology, the scientific journal of the American Academy of Neurology.

24 May 2004

Once-daily treatment with Alvesco (ciclesonide) in asthma patients has no effect on normal adrenal function

New data presented at the American Thoracic Society’s 2004 International Conference show that once-daily treatment with the investigational therapy Alvesco (ciclesonide) in mild-to-moderate asthma patients has no effect on normal adrenal function, as demonstrated by measurements of the hypothalamic-pituitary-adrenal (HPA)-axis.

24 May 2004

Connetics issued U.S. patent for emollient-foam technology

Connetics Corporation, a specialty pharmaceutical company that develops and commercializes dermatology products, announced today that on May 4, 2004 the United States Patent and Trademark Office (USPTO) issued to Connetics Patent No. 6,730,288 B1. The patent has 7 independent product claims, and covers a pharmaceutical aerosol foam composition having occlusive capability.

17 May 2004

New practice guidelines for treating fluid in the ears

Most toddlers and preschoolers will be diagnosed with fluid in their middle ears--or otitis media with effusion (OME)--at some time before school age.

3 May 2004

Psoriasis medications can treat more than the skin

The National Psoriasis Foundation, Dermatology Nurses Association, Dermatologists and People with Psoriasis have collaborated to offer a new resource to help people with psoriasis cope with the social and emotional impact of psoriasis.

27 Apr 2004

First generic cultivate(R) cream to receive tentative FDA approval

Atrix Laboratories, Inc. announced today the company received tentative approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for fluticasone propionate cream, 0.05%.