Craniofacial News and Research

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Alcohol consumption during pregnancy may cause subtle facial changes in babies says new study

According to a newly published study, consuming moderate amounts of alcohol during pregnancy may cause some distinct facial changes in babies. These subtle changes in the facial features of the babies are non-detectable with the naked eye said researchers. They can be detected using a 3D analysis they said. The changes in the facial features of the babies included those to the nose, lips and eyes that were picked up by the computer. These changes could be seen in babies whose mothers took any amount of alcohol during pregnancy.

7 Jun 2017

Stowers scientists provide evidence of cross-talk between Nanog and Hox genes

Competing regulatory genes "talk" to each other to maintain balance of cell state, according to new research from the Stowers Institute for Medical Research.

6 Jun 2017

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in about 1 in 4,000 births, causing the loss or duplication of up to 40 genes.

25 May 2017

NUS scientists develop novel handheld device for treatment of 'glue ear' in children

A team of researchers from the National University of Singapore has developed a novel handheld device, known as CLiKX, for the treatment of a condition called Otitis Media with Effusion, or 'glue ear', which is the leading cause of hearing loss and visits to the doctors among children worldwide.

24 May 2017

LSUHealthNO receives NIH grant to develop novel long-lasting dental filling materials

The National Institute of Dental and Craniofacial Research of the National Institutes of Health has awarded LSU Health New Orleans' School of Dentistry an R01 grant in the amount of $2,465,297 over five years to develop stronger, longer-lasting dental filling materials with antibacterial properties to inhibit recurrent cavities and extend the life of the restoration.

2 May 2017

USC study close to finding gene involved in cleft lip and palate

A group of researchers has found that three siblings born with cleft lip and palate share a common gene mutation associated with the birth defect.

22 Mar 2017

New approach could regenerate skull bone with better quality and no scar tissue

A team of researchers repaired a hole in a mouse's skull by regrowing "quality bone," a breakthrough that could drastically improve the care of people who suffer severe trauma to the skull or face.

8 Mar 2017

Study identifies potential therapeutic target for bone repair in adults with severe injury or disease

Irish scientists are developing an advanced technology to speed up bone repair in adults who have suffered severe fractures and bone degeneration.

1 Mar 2017

Researchers evaluate quality, methodology of randomized control trials pertaining to cleft lip and palate

A majority of healthcare studies are conducted using a randomized control trial (RCT). These trials randomly assign participants into groups who either receive or do not receive treatment. However, until the mid-1990s, some of these studies were falling victim to inadequate reporting, thereby causing confusing and potentially biased results.

9 Feb 2017

Combination assessment may rule out presence of OSA in children with Down syndrome

A combination of parental questionnaires and inexpensive diagnostic procedures that can be performed as part of a primary care visit may be able to rule out the presence of obstructive sleep apnea in people with Down syndrome.

26 Jan 2017

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Researchers from Massachusetts General Hospital led a large, international research team that has identified gene mutations associated with a rare congenital condition involving the absence of a nose and often accompanied by defects involving the eye and reproductive systems.

11 Jan 2017

FDI Dental World Federation's new definition of oral health announced

An editorial in the December issue of The Journal of the American Dental Association discusses the FDI Dental World Federation's new definition of oral health.

23 Dec 2016

Novel approach can regenerate dental pulp-like tissues in animal model

When a tooth is damaged, either by severe decay or trauma, the living tissues that comprise the sensitive inner dental pulp become exposed and vulnerable to harmful bacteria.

19 Dec 2016

Dental problems linked to cleft lip and palate may be caused by abnormal salivary glands

A new study in the Journal of Dental Research suggests that dental problems commonly associated with cleft lip and palate may be caused by abnormalities in salivary glands and an imbalance of immune compounds in the mouth.

7 Dec 2016

Study finds link between birth defects and antiepileptic drugs during pregnancy

A joint study conducted by researchers from the universities of Liverpool and Manchester has found a link between birth defects and certain types of epilepsy medication.

29 Nov 2016

Einstein researcher receives $7.5 million NIH grant to study genetics of congenital heart disease

The National Institutes of Health has awarded Bernice Morrow, Ph.D., at Albert Einstein College of Medicine and collaborators at the Children's Hospital of Philadelphia a five-year, $7.5 million grant to study the genetics of congenital heart abnormalities.

22 Nov 2016

SWAT team of immune cells linked to low infection rates after cleft lip and palate surgery in infants

The mouth is widely considered the dirtiest part of the human body, yet babies have surprisingly low infection rates following cleft lip and palate surgery.

18 Oct 2016

New 3-D printed biomaterial could be effective in treating children with bone defects

A Northwestern University research team has developed a 3-D printable ink that produces a synthetic bone implant that rapidly induces bone regeneration and growth. This hyperelastic "bone" material, whose shape can be easily customized, one day could be especially useful for the treatment of bone defects in children.

29 Sep 2016

Cleft palate repair costs the same for internationally adopted children

Since 2009, United States residents have adopted more children from China than any other country. Since China has a high prevalence of cleft lip and palate, some of these children require extra medical care early in their lives. Many prospective families are fearful of the treatment costs needed by a child affected by cleft lip and palate. However, recent research suggests that the costs are not nearly as high as previously thought.

29 Aug 2016

Whitehead Institute researchers identify cellular mechanisms involved in pre-mouth array formation

Whitehead Institute researchers have identified the pre-mouth array--an area of the developing face in embryonic frogs--that "unzips" to surround the mouth opening. Their work highlights the precision necessary to create the mouth and identifies the cellular mechanisms that drive its formation.

9 Aug 2016