Creatine News and Research

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Creatine is an endogenous amino acid which is synthesized from simpler amino acids, namely glycine, arginine and the sulfur-containing amino acid methionine. Approximately 95 percent of creatine in the body is stored in skeletal muscle.

Avicena receives orphan drug designation for Huntington's disease

The Avicena Group has announced today that the United States Food and Drug Administration (FDA) has granted orphan drug designation to HD-02, the company's proprietary drug candidate for the treatment of Huntington's disease.

23 Mar 2006

Six gene variants predict heart muscle damage after cardiac surgery

Duke University Medical Center researchers have found that patients with six specific variants of genes involved in the body's immune response are significantly more likely to suffer damage of heart tissue after cardiac surgery.

16 Nov 2005

Virginia Tech engineer investigates enzyme link to Huntington's, Parkinson's, and Alzheimer diseases

Several neurologically based afflictions, such as Huntington's, Parkinson's, and Alzheimer diseases, have been correlated to a higher than normal presence of a specific type of enzymes, called transglutaminases (TGase) in the human body.

30 Aug 2005

Nationwide survey reports a high rate of concern about body image in both boys and girls

A nationwide survey of more than 10,000 adolescents, published in the August issue of Pediatrics, reports a high rate of concern about body image in both boys and girls, and finds that adolescents with such concerns are much more likely to use hormones and dietary supplements to enhance their physique.

1 Aug 2005

Special imaging study shows failing hearts are energy starved

Using magnetic resonance spectroscopy (MRS) for the first time to examine energy production biochemistry in a beating human heart, Johns Hopkins researchers have found substantial energy deficits in failing hearts.

7 Feb 2005

Proof of principle that it is possible to deliver new genes body-wide to all the muscles of an adult animal

MDA-supported researchers at the University of Washington-Seattle have delivered the gene for the dystrophin protein to all voluntary muscles with a single intravenous injection in mice with Duchenne muscular dystrophy (DMD).

29 Jul 2004

MDA researchers find creatine helps in Duchenne dystrophy

Grip strength in the dominant hand and fat-free body mass (made mostly of muscle) increased when children with Duchenne muscular dystrophy (DMD) took the dietary supplement creatine at a dose of 0.1 grams per kilogram of body weight per day for four months.

25 May 2004

Matching method allows surgeons to successfully transplant kidneys that would otherwise be discarded

By carefully matching the estimated function of kidneys from deceased donors with the needs of potential recipients, surgeons can successfully transplant kidneys that would otherwise be discarded, according to a report from Wake Forest University Baptist Medical Center. The center was able to double its transplant volume within a year.

18 May 2004

Chemical thumbprint can help determine if tumor is returning or dying

Brain tumor survivors live with the constant worry that their cancer might come back. And even if they have a brain scan every few months to check, doctors often can't tell the difference between new cancer growth and tissue changes related to their treatment with radiation or chemotherapy.

3 May 2004

The muscle supplement creatine is safe, but not effective, in pediatric neuromuscular disease

The muscle supplement creatine can be safely taken by children with neuromuscular diseases, but does not improve strength or muscle mass, according to research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Researchers examine community-based drinkers rather than abstinent alcoholics

Almost all knowledge about brain damage due to chronic alcohol consumption has been gathered from alcoholics, who have generally been studied toward the end of their institutionalized treatment program (several weeks after their last drink) or many months into abstinence.

13 Apr 2004