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COVID-19 associated with increased risk of kidney damage, end-stage kidney diseases

A study by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System shows that people who have had COVID-19, including those with mild cases, are at an increased risk of developing kidney damage as well as chronic and end-stage kidney diseases.

1 Sep 2021

Systematic review: Efficacy and renal tolerability of ultrafiltration in acute decompensated heart failure

In a new publication from Cardiovascular Innovations and Applications, Yajie Liu and Xin Yuan from the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China consider the efficacy and renal tolerability of ultrafiltration in acute decompensated heart failure.

20 Aug 2021

Urine test for detecting chronic kidney disease is not used enough in high-risk groups, study suggests

Despite their higher risk of chronic kidney disease, people with hypertension or diabetes usually are not given a simple test for protein in the urine to screen for this potentially deadly disorder, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health.

19 Aug 2021

Excluding race factor from kidney function estimates may affect clinical outcomes for Black cancer patients

Removing race as a factor in a kidney function-estimating equation used to guide cancer treatment dosing and eligibility may decrease the proportion of Black patients recommended to receive full doses of anticancer drugs.

16 Aug 2021

Removal of race from kidney function estimates may negatively impact care for Black cancer patients

An accurate assessment of a patient's kidney function is critical for determining eligibility for anticancer treatments.

14 Aug 2021

Study compares the impacts of various race-free equations on kidney disease diagnoses

Equations that estimate individuals' kidney function currently include an adjustment for race. A study appearing in an upcoming issue of JASN compares various race-free equations and their expected impacts on kidney disease diagnoses.

29 Jul 2021

Excess caffeine intake may be linked to increased risk of osteoporosis

University of South Australia researchers have a bone to pick when it comes to drinking too much coffee as new research finds that excess caffeine may be linked to an increased risk of osteoporosis.

16 Jul 2021

mRNA-based COVID-19 vaccine CV07050101 demonstrates limited immunogenicity in non-human primates

Scientists from the US and Germany have recently evaluated the efficacy of an mRNA-based COVID-19 vaccine candidate, CV07050101, in inducing humoral and cellular immune responses in non-human primates. The study reveals that prime-boost immunization with the vaccine candidate induces only limited immunity against SARS-CoV-2.

12 Jul 2021

Is COVID-19 more severe in pregnancy?

A new study, released as a preprint on the medRxiv* server, indicates that pregnant women are more likely to develop severe disease following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

24 Jun 2021

Could urine tests predict kidney injury and mortality in COVID-19?

A team of scientists from the Columbia University, New York, has recently identified a potential biomarker to predict acute kidney injury in COVID-19 patients. By analyzing urine samples of 444 COVID-19 patients, they have revealed that the urinary level of neutrophil gelatinase-associated lipocalin (NGAL) can be used to determine the severity and duration of acute kidney and tubular injuries, as well as to predict the risk of mortality in acute COVID-19 patients.

15 Jun 2021

Kidney experts say it’s time to remove race from medical algorithms. Doing so is complicated.

Alphonso Harried recently came across a newspaper clipping about his grandfather receiving his 1,000th dialysis treatment. His grandfather later died — at a dialysis center — as did his uncle, both from kidney disease.

8 Jun 2021

Study reports safety, efficacy of targeted treatment for IgA nephropathy

IgA nephropathy (IgAN) is a chronic kidney disease occurring in young adults and is one of the most common reasons for kidney transplantation in this age group.

7 Jun 2021

Can depression increase the likelihood of rapid kidney function decline?

In a recent study, the presence of depressive symptoms in normally healthy individuals was found to correlate with rapid kidney function decline.

1 Jun 2021

Melatonin prevents kidney damage caused by metabolic complications of obesity

Scientists from the University of Granada (UGR), the Hospital Universitario La Paz (Madrid), and the University of Texas (USA) have taken an important step in the fight against kidney damage and its progression towards kidney failure, which is closely related to diabesity (obesity and its type 2 diabetes) and its complications.

27 May 2021

Which biomarkers can help predict adverse outcomes in COVID-19?

A team of researchers has conducted a systematic review to identify laboratory factors that can predict the risk of severe and critical COVID-19 as well as associated mortality rates. The team – from institutions in India and the USA – recently published their findings in the Journal of Clinical Medicine Research.

24 May 2021

Vegetarians may have a healthier biomarker profile than meat-eaters, indicates study

Vegetarians appear to have a healthier biomarker profile than meat-eaters, and this applies to adults of any age and weight, and is also unaffected by smoking and alcohol consumption, according to a new study in over 166,000 UK adults, being presented at this week's European Congress on Obesity (ECO), held online this year.

10 May 2021

SARS-CoV-2 clade linked to disease severity in the early phase of the pandemic

A new study in the journal JAMA Network reports on the disease severity associated with some clades of the virus, from an analysis of genomes from specimens isolated in the initial phase of the pandemic.

27 Apr 2021

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis.

15 Apr 2021

Study reports on two cats that caught COVID-19

Our feline friends are also vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to new research posted to the preprint server bioRxiv. The researchers diagnosed two cats living in France with mild symptomatic COVID-19 illness. The virus was most likely transmitted from their owners.

31 Mar 2021

Study reveals heightened mortality and racial disparities for cancer patients diagnosed with COVID-19

The COVID-19 and Cancer Consortium (CCC19) published new findings in the Annals of Oncology, showing heightened mortality and racial disparities for patients with cancer diagnosed with SARS-CoV-2 infection.

23 Mar 2021