Cyclophosphamide News and Research

RSS
Cyclophosphamide is a drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. It is also used to treat some types of kidney disease in children. Cyclophosphamide attaches to DNA in cells and may kill cancer cells. It is a type of alkylating agent. Also called CTX and Cytoxan.

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
FDA approves update to Rituxan label to include information on treatment of rare forms of vasculitis

FDA approves update to Rituxan label to include information on treatment of rare forms of vasculitis

Nanoparticles show promise in treatment for triple-negative breast cancer, finds study

Nanoparticles show promise in treatment for triple-negative breast cancer, finds study

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

NYU Langone's Perlmutter Cancer Center expands Blood and Marrow Transplant Program

NYU Langone's Perlmutter Cancer Center expands Blood and Marrow Transplant Program

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

Study shows new approach to improve survival rates for patients with stage IV Wilms tumors

Study shows new approach to improve survival rates for patients with stage IV Wilms tumors

Ludwig scientists develop and test individualized ovarian cancer vaccine

Ludwig scientists develop and test individualized ovarian cancer vaccine

Adjuvant AC chemotherapy found to be effective in treating HRD-positive breast cancer patients

Adjuvant AC chemotherapy found to be effective in treating HRD-positive breast cancer patients

Antibiotic use may affect efficacy of cancer immunotherapies

Antibiotic use may affect efficacy of cancer immunotherapies

Stem cell transplant can effectively treat patients with rare autoimmune disease, study shows

Stem cell transplant can effectively treat patients with rare autoimmune disease, study shows

Stem cell transplant improves survival among scleroderma patients

Stem cell transplant improves survival among scleroderma patients

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Immunotherapy combination offers new hope for women with early stage triple negative breast cancer

Immunotherapy combination offers new hope for women with early stage triple negative breast cancer

Study finds no clear benefit of stem-cell transplant for double-hit lymphoma patients in remission

Study finds no clear benefit of stem-cell transplant for double-hit lymphoma patients in remission

Hematologist-oncologist to lead bone marrow transplantation program for treating blood-borne cancers

Hematologist-oncologist to lead bone marrow transplantation program for treating blood-borne cancers

Timing of chemotherapy can have big effect on inflammation, study shows

Timing of chemotherapy can have big effect on inflammation, study shows

MUSC scientists design novel antibody-based therapy to fight against cancer

MUSC scientists design novel antibody-based therapy to fight against cancer

FDA approves expanded use of systemic therapy for treating chronic moderate-to-severe pediatric psoriasis

FDA approves expanded use of systemic therapy for treating chronic moderate-to-severe pediatric psoriasis

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

Researchers identify higher risk of early chemotherapy-related death in older patients with DLBCL

Researchers identify higher risk of early chemotherapy-related death in older patients with DLBCL