Cyclophosphamide News and Research

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Cyclophosphamide is a drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. It is also used to treat some types of kidney disease in children. Cyclophosphamide attaches to DNA in cells and may kill cancer cells. It is a type of alkylating agent. Also called CTX and Cytoxan.

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
Incidence of melanoma and other malignancies among rheumatoid arthritis patients treated with Methotrexate

Incidence of melanoma and other malignancies among rheumatoid arthritis patients treated with Methotrexate

New advance in use of oncolytic viruses as novel cancer treatments

New advance in use of oncolytic viruses as novel cancer treatments

Herceptin and chemotherapy improves response rates without major adverse effects in HER2 breast cancer

Herceptin and chemotherapy improves response rates without major adverse effects in HER2 breast cancer

Global Alliance for Pharmacogenomics

Global Alliance for Pharmacogenomics

Researchers study Rituximab's action on cancer stem cells

Researchers study Rituximab's action on cancer stem cells

Chemotherapy-induced anemia increases risk of local breast cancer recurrence

Chemotherapy-induced anemia increases risk of local breast cancer recurrence

Cardiac effects associated with breast cancer treatment appear lower with dose-dense chemotherapy

Cardiac effects associated with breast cancer treatment appear lower with dose-dense chemotherapy

Cardiac effects associated with breast cancer treatment appear lower

Cardiac effects associated with breast cancer treatment appear lower

Oncolytics Biotech announces new reovirus, cyclophosphamide research

Oncolytics Biotech announces new reovirus, cyclophosphamide research

Scientists identify and repress breast cancer stem cells in mouse tissue

Scientists identify and repress breast cancer stem cells in mouse tissue

New therapeutic options for newly diagnosed multiple myeloma patients

New therapeutic options for newly diagnosed multiple myeloma patients

Mild chemo before stem cell transplant causes long-term remission of follicular lymphoma

Mild chemo before stem cell transplant causes long-term remission of follicular lymphoma

Complete response with oblimersen combination improves survival of CLL patients

Complete response with oblimersen combination improves survival of CLL patients

Oncolytics Biotech receives approval for UK clinical trial of of REOLYSIN

Oncolytics Biotech receives approval for UK clinical trial of of REOLYSIN

Mayo Clinic clarifies diagnosis for primary central nervous system vasculitis (PCNSV)

Mayo Clinic clarifies diagnosis for primary central nervous system vasculitis (PCNSV)

Accentia announces investigational new drug application for Revimmune for refractory MS

Accentia announces investigational new drug application for Revimmune for refractory MS

PET scans accurately detect a breast tumor's response to chemotherapy

PET scans accurately detect a breast tumor's response to chemotherapy

New combo treatment for chronic lymphocytic leukaemia increases survival

New combo treatment for chronic lymphocytic leukaemia increases survival

Promising new therapy for protecting the fertility of women with cancer

Promising new therapy for protecting the fertility of women with cancer

High frequency of sperm abnormalities associated with reduced testicular volume in male lupus patients

High frequency of sperm abnormalities associated with reduced testicular volume in male lupus patients