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Study looks at the cellular basis for immune activation in fatigued breast cancer survivors

Breast cancer survivors who suffer from persistent, debilitating fatigue years after their diagnosis have something in common: their immune systems don't shut down following treatment, according to researchers at UCLA's Jonsson Cancer Center.

3 May 2006

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary.

3 May 2006

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

26 Apr 2006

Caspase-12 antagonists could potentially be useful in the treatment of sepsis and other inflammatory and immune disorders

According to the new study, the presence of caspase-12, which appears to modulate inflammation and innate immunity in humans, increases the body's "vulnerability to bacterial infection and septic shock" while a deficiency confers strong resistance to sepsis. This new discovery suggests that caspase-12 antagonists could be a potentially useful in the treatment of sepsis and other inflammatory and immune disorders.

26 Apr 2006

Discovery points to more effective ways of regulating cell signalling

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

20 Apr 2006

Scientists gain greater understanding of how embryos differentiate left from right

Researchers at the Forsyth Institute have discovered a new mechanism responsible for early left/right patterning, the process by which organs locate themselves on the left or right side of the body.

19 Apr 2006

Researchers suggest drug could block metastasis or reduce pain for bone cancer patients

An international research team has identified what may be a critical molecule in the ability of tumours to metastasize -- or spread -- into bone.

13 Apr 2006

IL-25 both promotes and limits inflammatory diseases

The same signal responsible for promoting the type of immune responses that cause asthma and allergy can also limit the type of inflammation associated with debilitating diseases like inflammatory bowel disease, arthritis and multiple sclerosis, according to researchers from the University of Pennsylvania School of Veterinary Medicine.

13 Apr 2006

Research explains why recipients of growth hormone therapy may develop colon polyps

The use of growth hormone therapy has been linked in some people to the development of colon polyps, a possible precursor to colorectal cancer - but medical researchers have debated the extent of a cancer risk.

11 Apr 2006

Protein loss linked to colon polyp risk from growth hormone

10 Apr 2006

Laughter is the best medicine

There's no doubt that laughter feels good, but is there real neurophysiology behind it and what can you do about it?

3 Apr 2006

First evidence that dendritic cells show unprecedented sensitivity to thimerosal

A team of cell biologists, toxicologists and molecular bioscientists at UC Davis has published a study connecting thimerosal with disruptions in antigen-presenting cells known as dendritic cells obtained from mice.

22 Mar 2006

Thalidomide, Lenalidomide show promise against Lou Gehrig's disease

New animal research suggests that two well-studied drugs, thalidomide and its derivative, lenalidomide, might extend the survival of patients with the neurological disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

9 Mar 2006

Attaching new cytokine to neural stem cells derived from bone marrow kills brain tumor cells

Attaching a recently discovered cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return.

1 Mar 2006

Cytokine News and Research

Study looks at the cellular basis for immune activation in fatigued breast cancer survivors

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

Caspase-12 antagonists could potentially be useful in the treatment of sepsis and other inflammatory and immune disorders

Discovery points to more effective ways of regulating cell signalling

Scientists gain greater understanding of how embryos differentiate left from right

Researchers suggest drug could block metastasis or reduce pain for bone cancer patients

IL-25 both promotes and limits inflammatory diseases

Research explains why recipients of growth hormone therapy may develop colon polyps

Protein loss linked to colon polyp risk from growth hormone

Laughter is the best medicine

First evidence that dendritic cells show unprecedented sensitivity to thimerosal

Thalidomide, Lenalidomide show promise against Lou Gehrig's disease

Attaching new cytokine to neural stem cells derived from bone marrow kills brain tumor cells

Australia boost preparedness for Avian Influenza

Selective T cell stimulation could help improve treatment of autoimmune disease and cancer

Anti-malarials most effective in lupus patients genetically at risk of high levels of TNF-alpha

Study may provide new hope for cancer patients

Protein finding could lead to new topical treatment for inflammatory diseases

Children could be saved from neuroblastoma using antibody therapy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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