Cytomegalovirus News and Research

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Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

Combination therapy shows promise in targeting latent HIV reservoirs

Combination therapy shows promise in targeting latent HIV reservoirs

Smoking, infection, and BMI found to significantly sway immune response, study shows

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study reveals the long-term effects of smoking on immunity

Study reveals the long-term effects of smoking on immunity

Promising new CMV vaccine shows stronger immune response

Promising new CMV vaccine shows stronger immune response

Experimental mRNA vaccine against CMV elicits promising immune responses

Experimental mRNA vaccine against CMV elicits promising immune responses

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Study finds patients with long COVID exhibit complement dysregulation with signs of thromboinflammation

Study finds patients with long COVID exhibit complement dysregulation with signs of thromboinflammation

The association between viral infections and glioma risk

The association between viral infections and glioma risk

Strengthening the immune system to fight cytomegalovirus on its own

Strengthening the immune system to fight cytomegalovirus on its own

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Pre-existing CMV immunity protects mothers and babies from transmission and birth defects

Pre-existing CMV immunity protects mothers and babies from transmission and birth defects

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

Genetics and environment influence immune responses to SARS-CoV-2

Genetics and environment influence immune responses to SARS-CoV-2

Pig kidney xenotransplantation continues to function well after 32 days

Pig kidney xenotransplantation continues to function well after 32 days

Researchers identify glycolipid that blocks infection with SARS-CoV-2 and RSV

Researchers identify glycolipid that blocks infection with SARS-CoV-2 and RSV

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Immune inflammatory reaction to COVID-19 may not be the underlying cause of long Covid

Immune inflammatory reaction to COVID-19 may not be the underlying cause of long Covid

Insights gained from genetically modified pig heart transplantation

Insights gained from genetically modified pig heart transplantation

Advances in influenza research

Advances in influenza research