Cytomegalovirus News and Research

RSS
Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

HIV-infected infants more likely to acquire congenital cytomegalovirus infection

HIV-infected infants more likely to acquire congenital cytomegalovirus infection

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Researchers begin trial to reduce risks of major cause of childhood disabilities

Researchers begin trial to reduce risks of major cause of childhood disabilities

Mechanical properties of viral DNA influence the course of infection, study finds

Mechanical properties of viral DNA influence the course of infection, study finds

Study could open new therapeutic avenues to attack herpesviruses

Study could open new therapeutic avenues to attack herpesviruses

Researchers find link between common 'harmless' virus and cardiovascular damage

Researchers find link between common 'harmless' virus and cardiovascular damage

New study finds key factors behind differences in immune responses

New study finds key factors behind differences in immune responses

Study highlights impact of silent viruses on how the host responds to vaccines

Study highlights impact of silent viruses on how the host responds to vaccines

Unique virus appears to enhance our immune system rather than weakening it

Unique virus appears to enhance our immune system rather than weakening it

Study uncovers unconventional killer T cells capable of combating viral infections

Study uncovers unconventional killer T cells capable of combating viral infections

Scientists explore factors that most affect our immune system

Scientists explore factors that most affect our immune system

New genomic tools provide better understanding of the human immune system

New genomic tools provide better understanding of the human immune system

New vaccine approach offers effective protection against tuberculosis

New vaccine approach offers effective protection against tuberculosis

Research could contribute to development of therapeutic drug and vaccine against malaria

Research could contribute to development of therapeutic drug and vaccine against malaria

Anti-aging protein could be used as target for rejuvenating cells in the immune system

Anti-aging protein could be used as target for rejuvenating cells in the immune system

Researchers to test use of ‘viral specific’ T-cells to target toxic viruses in children

Researchers to test use of ‘viral specific’ T-cells to target toxic viruses in children

Using biologics during pregnancy may not raise infant's risk for opportunistic infections

Using biologics during pregnancy may not raise infant's risk for opportunistic infections

New study explores how herpes simplex virus may change during familial transmission

New study explores how herpes simplex virus may change during familial transmission

Researchers create chimera virus that allows study of molecules to treat cancers

Researchers create chimera virus that allows study of molecules to treat cancers