Cytomegalovirus News and Research

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Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

UA physician-scientist to study how common stressors affect the aging process

UA physician-scientist to study how common stressors affect the aging process

Important biomarker may help in determining prognosis of brain cancer patients

Important biomarker may help in determining prognosis of brain cancer patients

Young patients with IBD have increased risk of severe viral infections

Young patients with IBD have increased risk of severe viral infections

Common cold virus could infect fetus via placenta

Common cold virus could infect fetus via placenta

Tailored T-cells safe, may be effective in preventing and treating multiple viral infections

Tailored T-cells safe, may be effective in preventing and treating multiple viral infections

US Government to fund development of a 'universal flu vaccine'

US Government to fund development of a 'universal flu vaccine'

Duke Human Vaccine Institute participates in a large national effort to improve flu shots

Duke Human Vaccine Institute participates in a large national effort to improve flu shots

Fullerene compounds effectively combat dangerous viral infections

Fullerene compounds effectively combat dangerous viral infections

U of M researcher wins $3.9 million NIH grant to study CMV vaccine strategies

U of M researcher wins $3.9 million NIH grant to study CMV vaccine strategies

Early neuroimaging essential for Zika-exposed infants

Early neuroimaging essential for Zika-exposed infants

UMD researchers connect a protein to antibody immunity for the first time

UMD researchers connect a protein to antibody immunity for the first time

Comprehensive gene activity database could significantly reduce animal use

Comprehensive gene activity database could significantly reduce animal use

Researchers gain insight into possible origins of 'ancient' immunological memory

Researchers gain insight into possible origins of 'ancient' immunological memory

CU Anschutz researchers identify new immunodeficiency disease

CU Anschutz researchers identify new immunodeficiency disease

Arc Bio introduces Galileo Pathogen Solution product line at ASM Clinical Virology Symposium

Arc Bio introduces Galileo Pathogen Solution product line at ASM Clinical Virology Symposium

Study describes new viral molecular evasion mechanism used by cytomegalovirus

Study describes new viral molecular evasion mechanism used by cytomegalovirus

Arc Bio launches unique NGS-based metagenomics platform for pathogen detection

Arc Bio launches unique NGS-based metagenomics platform for pathogen detection

German Research Foundation recently approves new research unit

German Research Foundation recently approves new research unit

Study reveals immune evasion strategy developed by cytomegaloviruses

Study reveals immune evasion strategy developed by cytomegaloviruses