Cytomegalovirus News and Research

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Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

Llama ‘nanobodies’ have the potential to outwit human cytomegalovirus

Llama ‘nanobodies’ have the potential to outwit human cytomegalovirus

Metabolomics: The Individual Metabolic Profile is the Key to Personalized Medicine

Metabolomics: The Individual Metabolic Profile is the Key to Personalized Medicine

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

Mother-to-baby SARS-CoV-2 transmission in pregnancy possible but rare, says study

Mother-to-baby SARS-CoV-2 transmission in pregnancy possible but rare, says study

New mobile app could be useful in assessing symptom severity in chronic fatigue syndrome

New mobile app could be useful in assessing symptom severity in chronic fatigue syndrome

Could microalgae-derived antiviral compounds combat SARS-CoV-2 and other viruses?

Could microalgae-derived antiviral compounds combat SARS-CoV-2 and other viruses?

New class of compounds can stop the reproduction of coronavirus

New class of compounds can stop the reproduction of coronavirus

Which vitamins and minerals help with COVID?

Which vitamins and minerals help with COVID?

International coalition develops classification criteria for 25 subtypes of uveitis

International coalition develops classification criteria for 25 subtypes of uveitis

The great promise of antiviral peptides against SARS-CoV-2

The great promise of antiviral peptides against SARS-CoV-2

UVA researchers shed new light on brain development

UVA researchers shed new light on brain development

Study sheds new light on human brain development

Study sheds new light on human brain development

Intranasal COVID-19 therapeutic shows promise in preclinical trials

Intranasal COVID-19 therapeutic shows promise in preclinical trials

A look at how coronavirus disease (COVID-19) affects Parkinson's

A look at how coronavirus disease (COVID-19) affects Parkinson's

Transplant recipients with COVID-19 may show lower cellular and antibody immune responses

Transplant recipients with COVID-19 may show lower cellular and antibody immune responses

Prior MMR or Tdap vaccination may reduce risk of severe COVID-19

Prior MMR or Tdap vaccination may reduce risk of severe COVID-19

Class I HLA alleles shape CD8+ T cell repertoire in SARS-CoV-2 infection

Class I HLA alleles shape CD8+ T cell repertoire in SARS-CoV-2 infection

COVID-19 pandemic has worsened global maternal and perinatal outcomes

COVID-19 pandemic has worsened global maternal and perinatal outcomes

Brain organoid models reveal mechanisms linked to virus-induced microcephaly

Brain organoid models reveal mechanisms linked to virus-induced microcephaly

Can COVID-19 cause hearing loss, vertigo, and tinnitus?

Can COVID-19 cause hearing loss, vertigo, and tinnitus?