Cytomegalovirus News and Research

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Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

Researcher is exploring safer and more effective treatment for leukemia

Researcher is exploring safer and more effective treatment for leukemia

Antimalarial drug shows in vitro activity against SARS-CoV-2 and flu viruses

Antimalarial drug shows in vitro activity against SARS-CoV-2 and flu viruses

Study explains why fetuses and newborns are mostly spared by COVID-19

Study explains why fetuses and newborns are mostly spared by COVID-19

LGC acquires The Native Antigen Company, strengthening its offer to the IVD sector

LGC acquires The Native Antigen Company, strengthening its offer to the IVD sector

Newly identified molecules can help develop COVID-19 therapeutics

Newly identified molecules can help develop COVID-19 therapeutics

Maternal SARS-CoV-2 infection not harmful in first trimester pregnancies

Maternal SARS-CoV-2 infection not harmful in first trimester pregnancies

Main receptors used by SARS-CoV-2 for cell entry are absent in the human placenta

Main receptors used by SARS-CoV-2 for cell entry are absent in the human placenta

Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer

Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer

Varied performance of SARS-CoV-2 antibody tests in detecting protective immunity

Varied performance of SARS-CoV-2 antibody tests in detecting protective immunity

CRISPR may help in kidney-transplants by detecting viruses

CRISPR may help in kidney-transplants by detecting viruses

Scientists model human CMV-induced microcephaly using brain organoids

Scientists model human CMV-induced microcephaly using brain organoids

One in five childhood deaths in England and Wales still due to infection

One in five childhood deaths in England and Wales still due to infection

Clinical factors during pregnancy associated with congenital CMV infection in newborns

Clinical factors during pregnancy associated with congenital CMV infection in newborns

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

UA physician-scientist to study how common stressors affect the aging process

UA physician-scientist to study how common stressors affect the aging process

Important biomarker may help in determining prognosis of brain cancer patients

Important biomarker may help in determining prognosis of brain cancer patients

Young patients with IBD have increased risk of severe viral infections

Young patients with IBD have increased risk of severe viral infections

Common cold virus could infect fetus via placenta

Common cold virus could infect fetus via placenta

Tailored T-cells safe, may be effective in preventing and treating multiple viral infections

Tailored T-cells safe, may be effective in preventing and treating multiple viral infections

US Government to fund development of a 'universal flu vaccine'

US Government to fund development of a 'universal flu vaccine'