Cytomegalovirus News and Research

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Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

Transplant recipients with COVID-19 may show lower cellular and antibody immune responses

Transplant recipients with COVID-19 may show lower cellular and antibody immune responses

Prior MMR or Tdap vaccination may reduce risk of severe COVID-19

Prior MMR or Tdap vaccination may reduce risk of severe COVID-19

Class I HLA alleles shape CD8+ T cell repertoire in SARS-CoV-2 infection

Class I HLA alleles shape CD8+ T cell repertoire in SARS-CoV-2 infection

COVID-19 pandemic has worsened global maternal and perinatal outcomes

COVID-19 pandemic has worsened global maternal and perinatal outcomes

Brain organoid models reveal mechanisms linked to virus-induced microcephaly

Brain organoid models reveal mechanisms linked to virus-induced microcephaly

Can COVID-19 cause hearing loss, vertigo, and tinnitus?

Can COVID-19 cause hearing loss, vertigo, and tinnitus?

Learning to live again: A Lazarus tale from the Covid front lines

Learning to live again: A Lazarus tale from the Covid front lines

COVID-19 and lung cancer have a common pathway, say researchers

COVID-19 and lung cancer have a common pathway, say researchers

New type of antibody marks infected cells, makes them visible to the immune system

New type of antibody marks infected cells, makes them visible to the immune system

Study shows accuracy of dried blood spot testing for detection of CMV infection in newborns

Study shows accuracy of dried blood spot testing for detection of CMV infection in newborns

Fetal and neonatal therapy combination may lessen the aftereffects of congenital CMV infection

Fetal and neonatal therapy combination may lessen the aftereffects of congenital CMV infection

COVID-19 has transformed the world of vaccines

COVID-19 has transformed the world of vaccines

Researchers design armored immune cells to attack recurring cancer in liver transplant patients

Researchers design armored immune cells to attack recurring cancer in liver transplant patients

Triple RNA sequencing dissects gene expression of virus and fungi in infection processes

Triple RNA sequencing dissects gene expression of virus and fungi in infection processes

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

Study reveals human protein that helps the immune system fight viral infections

Study reveals human protein that helps the immune system fight viral infections

Exciting findings on CD8 T cell response in recovered COVID patients

Exciting findings on CD8 T cell response in recovered COVID patients

Allowing low-level CMV infection may boost immunity in stem cell transplant recipients

Allowing low-level CMV infection may boost immunity in stem cell transplant recipients

Researchers find clues to successful immune response in the T cells of COVID-19 patients

Researchers find clues to successful immune response in the T cells of COVID-19 patients