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Researchers analyze neurodegeneration linked to FXTAS by measuring motor behavior

The neurological disorder FXTAS stems from a genetic premutation seen in one of every 151 women and one of every 468 men, called the FMR1 premutation.

17 Oct 2019

DNA origami: creating DNA-based nanomachines

DNA-based nanomachines are being created by DNA origami in several ways to create mechanical force at the scale of picoNewtons.

19 Sep 2019

New CRISPR tool enhances RNA editing

CRISPR-based tools helped revolutionize the ability to target genetic mutations linked to disease development. Such tools focus on using the enzymes Cas9 and Cas12 to target DNA, and Cas13 to target RNA. Now, scientists used a new CRISPR platform that expands the capabilities of RNA editing.

29 Jul 2019

Virus killing protein could be the real antiviral hero finds study

Researchers have identified a protein that can kill viruses and it forms the missing clue to the natural antiviral mechanism of the body that can target the viruses based on their genetic patterns. This newly identified protein is called KHNYN.

9 Jul 2019

Engineered stem cells offer new treatment for metastatic bone cancer

Engineered stem cells could help treat metastatic cancers in bone without killing normal surrounding bone.

9 Jul 2019

Study uncovers new way to identify driver genes important for cancer progression

Until now, researchers believed recurrent mutations (hotspot mutations) in cancer tumors were the important mutations (driver mutations) that promoted cancer progression.

29 Jun 2019

Scientists report new and improved method to detect chemical modifications to DNA

Ludwig Cancer Research scientists report in the current issue of Nature Biotechnology a new and improved method to detect chemical modifications to DNA.

26 Feb 2019

Lab instruments may leak valuable information, finds study

Lab instruments are important tools throughout research and health care. But what if those instruments are leaking valuable information?

25 Feb 2019

Researchers discover DNA modification that enhances our ability to extinguish fear

Researchers at The University of Queensland have discovered a DNA modification that enhances our ability to extinguish fear.

21 Feb 2019

Researchers describe first case of patient affected by dysfunctions in SLC28 gene family

A research team has described the first case of a patient affected by dysfunctions in a nucleoside transporter of the SLC28 gene family, which brings a set of genes which were not related to human pathologies in the scientific bibliography so far.

5 Feb 2019

Developing a Cervical Cancer Test That’s 100% Predictive

An interview with Professor Attila Lorincz, discussing the development of a new cervical cancer test that is able to predict cervical cancer and pre-cancer in 100% cases.

4 Feb 2019

New discovery will improve the safety and predictability of CRISPR

Scientists have discovered a simple set of rules that can be used to precisely predict how DNA will be modified by the CRISPR gene editing technique.

13 Dec 2018

Scientists decode the longest ever continuous DNA sequence

Scientists have decoded the longest continuous DNA sequence to date, measuring around 10,000 times longer than normal sequencing reads.

1 Nov 2018

Researchers discover epigenetic mechanism underlying ischemic cardiomyopathy

Researchers at the University of Alabama at Birmingham have shed light on an epigenetic reprogramming mechanism that underlies the development of ischemic cardiomyopathy.

13 Aug 2018

Researchers describe underlying mechanisms of congestive heart failure

Congestive heart failure is a terminal disease that affects nearly 6 million Americans. Yet its management is limited to symptomatic treatments because the causal mechanisms of congestive heart failure -- including its most common form, ischemic cardiomyopathy -- are not known.

10 Aug 2018

Researchers use guide RNAs to improve base editing system

Researchers have used guide RNAs to improve the adenine base editing (ABE) system, used by scientists to alter genetic codes in animal models of disease.

1 Aug 2018

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Inflammation is part of the body's natural healing process. But when it becomes chronic, inflammation can lead to cancer, Alzheimer's disease and other conditions.

26 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Research identifies new genetic variations that could indicate higher prostate cancer risk

As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent.

12 Jun 2018

New shape of DNA found in human cells

DNA double helix discovery is one of the major breakthroughs in human scientific history. Now in a new research, scientists have found that there may be another new shape in the DNA machinery within the cells of humans.

25 Apr 2018