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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Tuberculosis infection prevention by quick testing

With a new DNA test, tuberculosis infection can be revealed so quickly that a patient doesn’t have time to infect others. This can be an important key to effective control of the disease.

28 Sep 2005

Robots to shed light on sexual disease

It won’t be long before automated DNA test contribute to providing more knowledge about the up to now nearly unknown sexually transmitted mycoplasma – truly more widespread than chlamydia. Mycoplasma is a bacterial infection of the genitals.

28 Sep 2005

Equine flu virus jumps to dogs

A Cornell University virologist has isolated a highly contagious equine flu virus that is spreading a sometimes-fatal respiratory flu among dogs, and is responsible for a major dog-flu outbreak in New York state. There is no evidence that the virus could infect people.

27 Sep 2005

Gene variants and beta-blockers associated with increased risk of death

Patients with certain gene variants who were prescribed beta-blocker drugs after acute coronary syndrome (ACS) had an increased risk of death over the next three years, according to a study in the September 28 issue of Journal of the American Medical Association (JAMA).

27 Sep 2005

Possibility of tailored treatments for addiction based on how a person's genes behave

Scientists have learned how a genetic variation long suspected in making some people susceptible to alcoholism and narcotic drug addiction actually does so.

27 Sep 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine identified three novel mutations in two receptor tyrosine kinases in glioblastoma tumors using high throughput sequencing.

26 Sep 2005

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

"The findings bring us a step closer to developing targeted therapies for patients with high blood pressure who might otherwise be started on medications that won't help," said lead author Sandosh Padmanabhan, Ph.D.

26 Sep 2005

Mutations in the gene, called PIG-A may help identify individuals at high risk for cancer

A new study to detect an elevated rate of mutations in a gene on the X chromosome holds promise for developing a test that could identify individuals at risk for developing cancer.

26 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the current issue of the Journal of the National Cancer Institute.

22 Sep 2005

Simple organism can produce 10 trillion varieties of a single protein

A team led by University of California, San Diego biochemists has discovered the mechanism by which a simple organism can produce 10 trillion varieties of a single protein, a finding that provides a new tool to develop novel drugs.

21 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the September 21 issue of the Journal of the National Cancer Institute.

20 Sep 2005

Suppression of FOXO1a gene might kill resistant alveolar rhabdomyosarcoma (ARMS) tumors

FOXO1a caused death of tumor cells in laboratory study by triggering expression of caspase-3, which blocks cell division and causes cells to undergo apoptosis, according to St. Jude.

20 Sep 2005

Liverpool scientists have found a way of identifying families at high risk of pancreatic cancer

The team has developed a novel means of testing for pancreatic cancer that will enable doctors to treat the killer disease at its earliest stages. They are also now able to show how the risk of cancer for these patients changes with age.

20 Sep 2005

Prions rapidly 'remodel' good protein into bad

Two Brown Medical School biologists have figured out the fate of healthy protein when it comes in contact with the infectious prion form in yeast: The protein converts to the prion form, rendering it infectious. In an instant, good protein goes bad.

19 Sep 2005

First large-scale whole genome map of genetic variability associated with Parkinson's disease

Mayo Clinic researchers in collaboration with scientists at Perlegen Sciences, Inc. and funded by the Michael J. Fox Foundation for Parkinson's Research have produced the first large-scale whole genome map of genetic variability associated with Parkinson's disease.

19 Sep 2005

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Scientists from Maryland and New Jersey have identified a molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage.

19 Sep 2005

Study suggests chronic infections may create autoimmune response

New research finds the human immune system has foregone evolutionary changes that would allow it to produce better antibodies in less time because the improved antibodies would be far more likely to attack the body's own tissues.

19 Sep 2005

Researchers selectively knock out memory associations connected with receiving cocaine

Addicts crave drugs and suffer relapse not just because of the alluring high of drugs, but also because they are compelled by the powerful, haunting memory associations with the environment surrounding their drug taking. Thus, treatments that could eliminate those memory associations could prove effective in treating addiction, researchers believe.

19 Sep 2005

Vical and NIH to evaluate enhanced-delivery HIV vaccine

Vical Incorporated today announced plans to develop and evaluate electroporation-enhanced delivery of therapeutic and preventive DNA vaccines against HIV

12 Sep 2005

DNA News and Research

Further Reading

Tuberculosis infection prevention by quick testing

Robots to shed light on sexual disease

Equine flu virus jumps to dogs

Gene variants and beta-blockers associated with increased risk of death

Possibility of tailored treatments for addiction based on how a person's genes behave

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

Mutations in the gene, called PIG-A may help identify individuals at high risk for cancer

Change in gene may be underlying molecular defect in some colorectal cancers

Simple organism can produce 10 trillion varieties of a single protein

Change in gene may be underlying molecular defect in some colorectal cancers

Suppression of FOXO1a gene might kill resistant alveolar rhabdomyosarcoma (ARMS) tumors

Liverpool scientists have found a way of identifying families at high risk of pancreatic cancer

Prions rapidly 'remodel' good protein into bad

First large-scale whole genome map of genetic variability associated with Parkinson's disease

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Study suggests chronic infections may create autoimmune response

Researchers selectively knock out memory associations connected with receiving cocaine

Vical and NIH to evaluate enhanced-delivery HIV vaccine

Michael Stryker

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