DNA Damage News and Research

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New clues about BRCA1 role in breast cancer

A breast cancer gene's newly discovered role in repairing damaged DNA may help explain why women who inherit a mutated copy of the gene are at increased risk for developing both breast and ovarian cancer.

17 Jan 2008

Genetic evolution of tumours according to their growth dynamics.

A study co-directed by the Universidad Complutense de Madrid and La Paz hospital in Madrid identifies a protein of high expression in cells located at the tumour boundary that could play an essential role in the evolution of tumours and their invasive potential.

11 Jan 2008

Breast cancer gene mutation more common in Hispanic, young black women

A genetic mutation already known to be more common in Ashkenazi Jewish breast cancer patients is also prevalent in Hispanic and young African-American women with breast cancer, according to one of the largest, multiracial studies of the mutation to date.

28 Dec 2007

Stem cells train heart following heart attack

Following a heart attack, part of the heart tissue dies. It is still not possible to restore the scar tissue arising as a result of this. The majority of stem cell researchers attempt to make new heart muscle cells from stem cells.

27 Nov 2007

Alcohol and second-hand smoke a deadly combo

According to a new study the combination of alcohol and second-hand smoke can cause damage to the heart.

26 Nov 2007

Study looks at effects of smoking and breathing second-hand smoke along with drinking

Tobacco smoke-filled air is bad for cardiovascular health, and drinking alcohol at the same time only makes it worse, according to researchers at the University of Alabama at Birmingham (UAB).

21 Nov 2007

Carbon monoxide counteracts one side-effect of an anti-cancer drug

Doxorubicin (DOX) is a red-colored anticancer drug that carries serious side effects for the heart, including cardiac muscle deterioration (cardiomyopathy) and scar tissue accumulation in the heart (fibrosis).

21 Nov 2007

Melatonin could actually be hurting you at night!

What do you do when a naturally occurring hormone in your body turns against you? What do you do when that same hormone - melatonin - is a popular supplement you take to help you sleep?

16 Nov 2007

Manipulation of MOF enzyme may make tumors more sensitive to radiation therapy

To make tumors more sensitive to the killing power of radiation is a key aspiration for many radiation oncologists. Researchers at Washington University School of Medicine in St. Louis have uncovered new information that leads them closer to that goal.

5 Nov 2007

Chemical peroxynitrite tolerates pain

The repeated use of opiate drugs such as morphine to relieve chronic pain results in individuals having to take higher and higher doses of the drug to achieve equivalent pain relief (they are said to exhibit antinociceptive tolerance).

2 Nov 2007

Extract from broccoli protects skin sun damage

U.S. researchers have discovered that as well as being healthy food, broccoli also helps skin cells fight off damage caused by harmful ultraviolet radiation.

23 Oct 2007

Sex once a day... on doctors orders!

The latest research into male fertility has the news all men want to hear - the more sex a man has the more fertile he becomes - at least in some cases!

17 Oct 2007

Enhanced DNA-repair mechanism can cause breast cancer

Although defects in the "breast cancer gene," BRCA1, have been known for years to increase the risk for breast cancer, exactly how it can lead to tumor growth has remained a mystery.

16 Oct 2007

Chlamydia makes men infertile

One of the most common sexually transmitted diseases may be damaging the fertility of British males.

15 Oct 2007

Cancer researchers investigate free radicals

The University of Leicester has been selected as the hub of a worldwide network of researchers to investigate one of the causes of cancer.

11 Oct 2007

How cells protect themselves (or not) from DNA damage caused by UV rays

It's well known that overexposure to ultraviolet rays from the sun can cause major skin problems, ranging from skin cancer to sunburns and premature wrinkles.

2 Oct 2007

Worm study sheds light on how the human body ages

Microscopic worms used for scientific research are living longer despite cellular defects, a discovery that is shedding light on how the human body ages and how doctors could one day limit or reverse genetic mutations that cause inherited diseases, according to a new University of Colorado at Boulder study.

2 Oct 2007