DNA Damage News and Research

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Sperm from diabetic men have greater levels of DNA damage which may affect their fertility

In the first study to compare the quality of DNA in sperm from diabetic and non-diabetic men, researchers at Queen’s University Belfast showed that the DNA in the nuclei of the sperm cells had greater levels of fragmentation in diabetic men, and that there were more deletions of DNA in the tiny, energy-generating structures in the cells called mitochondria.

8 May 2007

Diabetes damages DNA in men's sperm and may affect fertility

Scientists have found that sperm from diabetic men have greater levels of DNA damage than sperm from men who do not have the disease.

4 May 2007

M. D. Anderson wins $8.3-million to research environmental causes of major diseases

An $8.3-million federal grant to The University of Texas M. D. Anderson Cancer Center Science Park - Research Division addresses the complex interplay between such varied factors as genetics, diet, and environmental exposure to toxins that cause cancer, asthma, diabetes, cardiovascular and other diseases.

21 Apr 2007

Nanoparticles could damage DNA and lead to cancer

Tissue studies indicate that nanoparticles, engineered materials about a billionth of a meter in size, could damage DNA and lead to cancer, according to research presented at the 2007 Annual Meeting of the American Association for Cancer Research.

18 Apr 2007

Connection between cancer development and Darwinian evolution explored

Cancer is a natural consequence of human evolution. Our genes have not developed to give us long and happy lives.

17 Apr 2007

Lilly and AACR tackle cancer together

Innovative and collaborative cancer research can be the catalyst to improving patient outcomes.

17 Apr 2007

Researchers probe checkpoint signaling responses in unprecedented ways

As published in the April 15th issue of Genes & Development, Dr. Karlene Cimprich and colleagues at Stanford University have determined the minimal DNA structure sufficient to activate the ATR-mediated DNA damage checkpoint.

16 Apr 2007

Study suggests reason for high incidence of cancer in the prostate

Cancer occurs more frequently in the prostates of men than in any organ other than the skin. While DNA damage caused by exposure to the sun is likely the cause of many skin cancers, the cause of prostate cancer remains largely unknown.

12 Apr 2007

Recognition for cancer researchers

World-class cancer researchers whose science has significantly contributed to progress in the fight against cancer will be recognized April 14-18, 2007, by the American Association for Cancer Research (AACR) at its 2007 Annual Meeting in Los Angeles, Calif.

3 Apr 2007

Unusual protein helps cell bypass damage when making new DNA

Scientists have discovered how an unusual protein helps a cell bypass damage when making new DNA, thereby averting the cell's self-destruction.

3 Apr 2007

Gender differences and skin cancer

Inherent gender differences – instead of more sun exposure – may be one reason why men are three times more likely than women to develop certain kinds of skin cancer, say researchers at Ohio State University Medical Center.

2 Apr 2007

Effect of gender on the development of UVB-induced skin cancers

Inherent gender differences "instead of more sun exposure" may be one reason why men are three times more likely than women to develop certain kinds of skin cancer, say researchers at Ohio State University Medical Center.

2 Apr 2007

DNA repair runs by the biological clock

No sooner have the clocks gone forward than scientists have shed new light on the link between our biological clocks and DNA damage repair processes, essential in protecting our cells from cancer.

27 Mar 2007

Pioneer work on cellular response to DNA Damage wins GlaxoSmithKline award

The Biochemical Society's GlaxoSmithKline Award 'for distinguished research leading to new advances in medical science' goes to Stephen Jackson (University of Cambridge) for his pioneering work on cellular response to DNA damage.

22 Mar 2007

New dimension to understanding of p53 protein

The p53 protein routinely shuts down damaged cells and is one of our main lines of defence against cancer. Scientists at Karolinska Institutet in Sweden now present new findings on how p53 carries out this all-important function.

21 Mar 2007

Novel pathway for antibiotic-induced cell death

Scientists have identified unforeseen mechanisms by which quinolones - a family of broad-spectrum antibiotics among the most widely prescribed - induce bacterial cell death.

13 Mar 2007

The need for a bronzed glow could be in the genes

Researchers have found that a gene which helps to control tumours also triggers the chemical chain reaction that makes the skin tan when exposed to ultraviolet (UV) light.

12 Mar 2007

Scientists identify specific enzymes that make meningitis hard to fight

Two enzymes in meningitis bacteria which prevent the body from successfully fighting off the disease, and make the infection extremely virulent, have been identified in new research published today.

22 Feb 2007

Watercress shows anti-cancer potential

Eating watercress daily can significantly reduce DNA damage to blood cells, which is considered to be an important trigger in the development of cancer, University of Ulster scientists revealed.

18 Feb 2007

Variation in gene caspase-8 may help protect against breast cancer

A large-scale analysis of data on breast cancer risk has concluded that a common variation in the gene caspase-8 (CASP8) is associated with a somewhat lower risk of the disease. Variants are small changes that occur in a gene sequence.

13 Feb 2007