DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Scientists receive $1.6 million grant to study impact of phthalate exposure on male fertility

A cross-disciplinary team of scientists, led by University of Massachusetts Amherst environmental epigeneticist Richard Pilsner, will use a three-year, $1.6 million grant from the National Institute of Environmental Health Sciences to expand research into the impact of phthalate exposure on male fertility.

30 Oct 2019

NYU Langone Health launches new molecular assay to identify patients with brain tumors

NYU Langone Health and its Perlmutter Cancer Center have launched clinical whole genome DNA methylation profiling for patients with brain tumors.

24 Oct 2019

Parents' behavior can have substantial impact on developing oxytocin systems in babies

Oxytocin is an extremely important hormone, involved in social interaction and bonding in mammals, including humans.

24 Oct 2019

Measuring development in young children: the DNA clock

Scientists have come up with a new discovery that could transform our understanding of how childhood growth and development are measured – the DNA clock. The study, published in the Proceedings of the National Academy of Science, is the first paper to...

16 Oct 2019

Epigenetic changes can lead to development of GISTs, other cancers

Most cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be effectively targeted with drugs that inhibit the activity of rogue cancer-promoting enzymes.

16 Oct 2019

New molecular "clock" could help monitor life-altering development disorders in children

Scientists have developed a molecular "clock" that could reshape how pediatricians measure and monitor childhood growth and potentially allow for an earlier diagnosis of life-altering development disorders.

15 Oct 2019

Researchers reveal mechanism involved in altering DNA methylation in cancer

Understanding the mechanisms that mediate widespread DNA damage in the cancer genome is of great interest to cancer physicians and scientists because it may lead to improved treatments and diagnosis. In this study, a multi-institutional team led by researchers at Baylor College of Medicine has brought attention to genomic structural variation as a previously unappreciated mechanism involved in altering DNA methylation, a form of gene control, in human cancers.

15 Oct 2019

Finnish study offers new information about molecular mechanisms of Alzheimer's disease

Researchers have discovered new changes in blood samples associated with Alzheimer's disease. A new international study was conducted on disease-discordant Finnish twin pairs: one sibling suffering from Alzheimer's disease and the other being cognitively healthy.

15 Oct 2019

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

In continuing efforts to find novel ways to kill cancer cells, researchers at the University of Maryland School of Medicine have identified a new pathway that leads to the destruction of cancer cells.

14 Oct 2019

Men should stay alcohol-free for at least six months before conception

A new study has revealed that men hoping to conceive should stop drinking for at least six months before to prevent congenital heart diseases.

4 Oct 2019

Researchers elucidate enzymes that control long-term memory, learning process in the brain

When we first purchase a smart phone, all of our settings and applications are the same. But as time passes, everyone's phones will change drastically as we adapt them to our own individual needs and preferences. In the same way, our memories and life experiences are loaded into our brains, making one person unique from another.

2 Oct 2019

PWSA (USA) announces support for H.R.4144 - Ending the Diagnostic Odyssey Act of 2019

Today, PWSA (USA) announced its support for H.R.4144 - Ending the Diagnostic Odyssey Act of 2019, a bill to enable States to better provide access to whole genome sequencing clinical services for certain undiagnosed children under the Medicaid program, and for other purposes.

27 Sep 2019

Love hormone oxytocin linked to hypersexuality

Sex addiction or hypersexual disorder is a behavior characterized by an excessive preoccupation with sexual fantasies, behaviors, or urges that are hard to control, causing negative effects on one’s health and relationships.

25 Sep 2019

Study uncovers epigenetic origins for hypersexual disorder

A new study has shown that epigenetic changes lead to overactivity of the hormone oxytocin, and this is a key element in hypersexual disorder.

24 Sep 2019

Study reveals possible role of hormone oxytocin in hypersexual disorder

A new study of men and women with hypersexual disorder has revealed a possible role of the hormone oxytocin, according to results published in the journal Epigenetics.

23 Sep 2019

Artificial intelligence helps improve diagnosis of head and neck cancers

Researchers from Charité - Universitätsmedizin Berlin and the German Cancer Consortium have successfully solved a longstanding problem in the diagnosis of head and neck cancers.

12 Sep 2019

Salk researchers develop method to reveal epigenetic features of brain cells

The brain's prefrontal cortex, which gives us our ability to solve problems and plan ahead, contains billions of cells. But understanding the large diversity of cell types in this critical region, each with unique genetic and molecular properties, has been challenging.

10 Sep 2019

DNA methylation closely linked to telomere length

Aging is associated with multiple disease conditions. Recently it has been found that many of these illnesses are linked to the length of the telomeres at the ends of every chromosome. Telomere length (TL) is affected by both genetic and epigenetic contributions.

2 Sep 2019

Cannabis use may alter gene linked to autism in male sperm

Researchers from Duke University Medical centre, Durham, USA have come up with an important study that shows that use of cannabis among men could alter a specific gene in their sperm that is linked to autism. The study titled, “Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm,” and is published in the latest issue of the journal Epigenetics.

28 Aug 2019

Swallowable balloon device for early detection of Barrett's esophagus receives FDA 510K clearance

Investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center developed the test for early detection of Barrett's esophagus that offers promise for preventing deaths from esophageal adenocarcinoma.

21 Aug 2019

DNA Methylation News and Research

Further Reading

Scientists receive $1.6 million grant to study impact of phthalate exposure on male fertility

NYU Langone Health launches new molecular assay to identify patients with brain tumors

Parents' behavior can have substantial impact on developing oxytocin systems in babies

Measuring development in young children: the DNA clock

Epigenetic changes can lead to development of GISTs, other cancers

New molecular "clock" could help monitor life-altering development disorders in children

Researchers reveal mechanism involved in altering DNA methylation in cancer

Finnish study offers new information about molecular mechanisms of Alzheimer's disease

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

Men should stay alcohol-free for at least six months before conception

Researchers elucidate enzymes that control long-term memory, learning process in the brain

PWSA (USA) announces support for H.R.4144 - Ending the Diagnostic Odyssey Act of 2019

Love hormone oxytocin linked to hypersexuality

Study uncovers epigenetic origins for hypersexual disorder

Study reveals possible role of hormone oxytocin in hypersexual disorder

Artificial intelligence helps improve diagnosis of head and neck cancers

Salk researchers develop method to reveal epigenetic features of brain cells

DNA methylation closely linked to telomere length

Cannabis use may alter gene linked to autism in male sperm

Swallowable balloon device for early detection of Barrett's esophagus receives FDA 510K clearance

DNA Methylation eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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