Dehydroepiandrosterone News and Research

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Dehydroepiandrosterone is a substance being studied in the prevention of cancer. It is a type of steroid. Also called DHEA.

Natural compound found in red wine can lower testosterone levels in women with PCOS

Resveratrol—a natural compound found in red wine and grapes—can help address a hormone imbalance in women with polycystic ovary syndrome (PCOS), a leading cause of infertility in women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

19 Oct 2016

Changes in the brain make people prone to alcoholism

The brain tissue of persons with alcohol dependence shows a variety of changes compared to non-alcoholic control persons. All alcoholics' brains share some characteristics, but some are exclusive to the brain tissue of anxiety-prone type 1 alcoholics or impulsive type 2 alcoholics, according to a recent study from the University of Eastern Finland.

29 Apr 2016

New phase III trial takes intravaginal DHEA a step closer to approval

A new phase III trial with positive results is taking intravaginal DHEA a step closer to governmental approval. The formulation could provide women who cannot or do not wish to use intravaginal estrogen with an effective vaginal alternative for easing vaginal symptoms and pain with sex after menopause.

5 Jan 2016

IU researchers discover hormonal mechanism that links short winter days with increased aggression in females

Indiana University researchers have discovered a hormonal mechanism in hamsters that connects short winter days with increased aggression in females, and that it differs from the mechanism that controls this same response in males.

18 Nov 2015

Cholesterol-lowering statin drugs could delay prostate cancer growth in patients receiving ADT

Men who went on cholesterol-lowering statin drugs when they began androgen deprivation therapy for prostate cancer had a longer time in which their disease was under control than did men who didn't take statins, a clinical trial led by Dana-Farber Cancer Institute investigators shows.

8 May 2015

Endocrine Society issues updated Clinical Practice Guideline on androgens in women

The Endocrine Society today issued a Clinical Practice Guideline (CPG) advising against the use of testosterone therapy in healthy women.

5 Oct 2014

Relationship between stress hormones and immune function across different stages in life

Young people have a more robust immune response to the loss of a loved one, according to new research from the University of Birmingham, providing insight into how different generations cope with loss.

10 Sep 2014

Androgen sensitivity may contribute to hypertrichosis in girls

Prepubertal girls with hypertrichosis are likely to have genetic variants of the androgen receptor known to be particularly sensitive to androgen, say researchers.

16 Jun 2014

Mental exercise may help prevent cognitive decline in healthy older adults

Cognitive training exercises - or mental exercise - may help prevent cognitive decline in healthy older adults, while evidence for the benefits of pharmacologic substances and exercise is weak, outlines a review published in CMAJ.

16 Apr 2013

Low DHEA-S levels may increase risk of heart and blood-vessel disease in elderly men

Low levels of a naturally occurring steroid are associated with an increased risk of heart and blood-vessel disease in elderly men, a new study finds. The results will be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston.

25 Jun 2012

Low doses of DHEA may help relieve menopausal symptoms in women

Leading age management facility, Cenegenics Carolinas, located in Charleston and Charlotte is encouraged by a recent study suggesting low doses of the hormone DHEA may help sexual function and menopausal symptoms in women.

25 Jan 2012

DHEA hormone may help a woman's menopausal symptoms, sex life

A new study has shown that the DHEA, a hormone mostly secreted by the adrenal glands, may be able to help a woman's menopausal symptoms, as well as giving her a better sex life.

20 Dec 2011

Infants treated with certain HIV medication more likely to experience adrenal dysfunction

Infants of human immunodeficiency virus 1 (HIV-1) infected mothers who were treated before and after birth with the protease inhibitor lopinavir-ritonavir were more likely to experience adrenal dysfunction, including life-threatening adrenal insufficiency in premature infants, compared with a zidovudine-based regimen, according to a preliminary report in the July 6 issue of JAMA.

6 Jul 2011

Ipsen decides to assess development of Irosustat in combination with hormonal therapies

Ipsen today announced its decision to assess the alternative development of Irosustat (BN 83495) in combination with other hormonal therapies. This decision is based on the futility analysis from the proof-of-concept trial phase II clinical study carried out in Europe in monotherapy in endometrial cancer, and on the phase I/II clinical study results obtained in metastatic prostate and breast cancers.

6 Jun 2011

New non-invasive blood test may detect early stage Alzheimer's

A new blood test that will diagnose Alzheimer's disease may soon hit the market, thanks to an innovative study from the Research Institute of the McGill University Health Centre.

4 May 2011

Researchers block central pathway for prostate cancer progression

Prostate cancer advances when tumors become resistant to hormone therapy, which is the standard treatment for patients, and begin producing their own androgens.

21 Jul 2010

Scientists find way to block androgens, halt tumor progression in prostate cancer

Prostate cancer advances when tumors become resistant to hormone therapy, which is the standard treatment for patients, and begin producing their own androgens. Researchers at UT Southwestern Medical Center have found that blocking one of the enzymatic steps that allow the tumor to produce androgens could be the key in halting a tumor's growth.

21 Jul 2010

Anti-aging supplement: A fountain of hope for would-be mothers

According to the American Pregnancy Association, six million women a year deal with infertility. Now, a Tel Aviv University study is giving new hope to women who want to conceive ― in the form of a pill they can find on their drugstore shelves right now.

2 Jul 2010

Ipsen announces preliminary results of phase I trial in metastatic breast cancer with BN83495

Ipsen today announced the preliminary results of a phase I trial in metastatic breast cancer with BN83495, Ipsen’s lead and first-in-class orally available irreversible steroid sulfatase (STS) inhibitor.

14 Dec 2009

Initiation of Phase II clinical trial to evaluate the efficacy of BN83495 announced

Ipsen today announced the initiation of an international, multi-center, controlled, randomized Phase II clinical trial to evaluate the safety and efficacy of BN83495, its investigational first-in-class steroid sulfatase (STS) inhibitor, in advanced endometrial cancer.

25 Nov 2009