Depressive Disorder News and Research

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Genetic variation influencing chromatin states associated with neuropsychiatric disorders

A new study led by NorthShore University HealthSystem and the University of Chicago took a novel approach to identifying SNPs influencing the risk of neuropsychiatric disorders like schizophrenia, bipolar and major depressive disorder, the institutions announced today.

4 Aug 2020

Anti-inflammatory Tetracycline activity may modulate COVID-19 severity

The current COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), seems to attack the human airway epithelium primarily. In severely affected patients, the illness progresses to hypoxemic respiratory failure and acute respiratory distress syndrome (ARDS). The latter is treatable mainly by supportive management.

30 Jul 2020

Individuals exposed to early life stress more likely to develop youth-onset depression

A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, reports that individuals exposed to early life stress (ELS) were more likely to develop a major depressive disorder (MDD) in childhood or adolescence than individuals who had not been exposed to ELS.

15 Jul 2020

McLean Hospital study compares the costs and benefits of esketamine

A paper authored by researchers from McLean Hospital has determined that esketamine, a nasal spray to treat severe depression, is currently too expensive for widespread use.

13 Jul 2020

Magstim acquires Electrical Geodesics, Inc. (EGI) product portfolio

Magstim, the global leader in Transcranial Magnetic Stimulation (TMS), today announced an agreement to acquire the product portfolio of Electrical Geodesics, Inc. (EGI) from Royal Philips, a global leader in health technology.

From Magstim Inc. 6 Jul 2020

Study shows changes in brain dynamics at rest following a relationship breakup

During a person's life, the experience of a stressful life event can lead to the development of depressive symptoms, even in a non-clinical population.

21 Jun 2020

Researchers examine parental history of suicidal behavior in young children

Suicide is the second leading cause of death for persons ages 10-24. And according to the Centers for Disease Control and Prevention (CDC), youth suicide rates have nearly tripled from 2007 to 2017.

12 Jun 2020

Fish oil may be an effective treatment for depression, study shows

A study published in Molecular Psychiatry shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication.

11 Jun 2020

Effects of chronic stress associated with increased inflammatory signaling within brain circuits

Anxiety and depression are significantly heightened during times of great stress such as the COVID-19 pandemic.

4 Jun 2020

COVID-19 pandemic has worsened pre-existing mental health conditions

With over 6.26 million cases and 375,000 deaths in just five months, the COVID-19 pandemic has caused great fear and devastation in many parts of the world. Many studies show that, generally, there has been an accompanying increase in fear, anxiety, and depressive symptoms during this period. Now, a new study published on the online preprint server medRxiv in May 2020 shows that patients with a history of mental ill-health often underwent a worsening of their symptoms with the onset of the pandemic.

1 Jun 2020

Schizophrenia related to abnormal fatty metabolism in the brain

Researchers discovered a brain deficiency in people with schizophrenia that could lead to development of new drug therapies.

28 Apr 2020

Natural mood regulation is impaired in people with depression, research shows

Periods of lockdown during the COVID-19 situation likely to exacerbate problems with mood regulation, say experts at the University of Oxford.

22 Apr 2020

Review: The effect of probiotics in ameliorating altered CNS functions in neurological disorders

As per the WHO report, one in every four people are affected by a mental or neurological disorder at some point in their lives making mental disorders among the leading cause of ill-health and disability worldwide.

15 Apr 2020

Depressive disorders in patients with HIV/AIDS often go unrecognized or untreated

People living with HIV/AIDS are at increased risk of depressive disorders. But all too often, these conditions go unrecognized or untreated, suggests a literature review in the May/June issue of Harvard Review of Psychiatry.

7 Apr 2020

TMS shows promise as treatment for adults with both depression and autism

In a pilot study in adults with autism and depression, transcranial magnetic stimulation, or TMS, was effective in reducing depressive symptoms and had some effects on autistic symptoms, report researchers at the Medical University of South Carolina in Autism Research.

7 Apr 2020