Diabetes Mellitus News and Research

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Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.
Scientists discover genetic variations that have a drastic impact on small molecules

Scientists discover genetic variations that have a drastic impact on small molecules

Study shows how intestinal stem cells constantly renew and give rise to specialized cell types

Study shows how intestinal stem cells constantly renew and give rise to specialized cell types

Six clearly distinguishable subtypes of prediabetes identified

Six clearly distinguishable subtypes of prediabetes identified

FDA approves first generic glucagon for injection to treat severe hypoglycemia

FDA approves first generic glucagon for injection to treat severe hypoglycemia

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

New screening platform can be used to discover more effective drugs for type 1 diabetes

New screening platform can be used to discover more effective drugs for type 1 diabetes

Neanderthal gene variant increases risk of severe COVID-19

Neanderthal gene variant increases risk of severe COVID-19

Obesity increases the risk of severe COVID-19, study finds

Obesity increases the risk of severe COVID-19, study finds

Atrial fibrillation patients should avoid heavy alcohol consumption, warns study

Atrial fibrillation patients should avoid heavy alcohol consumption, warns study

Researchers develop telomerase gene therapy for treating different pathologies

Researchers develop telomerase gene therapy for treating different pathologies

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Could the keto diet help prevent or mitigate severe COVID-19?

Could the keto diet help prevent or mitigate severe COVID-19?

Body mass index and severe COVID-19

Body mass index and severe COVID-19

COVID-19's harmful neurological effects are more common in patients with hypertension, diabetes

COVID-19's harmful neurological effects are more common in patients with hypertension, diabetes

Manipulating mitochondria to improve the efficiency of neuronal reprogramming

Manipulating mitochondria to improve the efficiency of neuronal reprogramming

Clinical trials show SGLT2 inhibitor may benefit patients with type 2 diabetes

Clinical trials show SGLT2 inhibitor may benefit patients with type 2 diabetes

Modifiable risk factors in the first 1000 days of life predict higher adiposity and cardiometabolic risk

Modifiable risk factors in the first 1000 days of life predict higher adiposity and cardiometabolic risk

Tomocube’s HT-2 microscope quantifies therapeutic effects of targeted nanodrugs against atherosclerosis

Tomocube’s HT-2 microscope quantifies therapeutic effects of targeted nanodrugs against atherosclerosis

Underrepresented minorities are at increased risk for AL amyloidosis

Underrepresented minorities are at increased risk for AL amyloidosis

Study finds diabetes epidemic among Xavante indigenous community in Central Brazil

Study finds diabetes epidemic among Xavante indigenous community in Central Brazil