Diabetes Mellitus News and Research

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Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.
Variations in human ACE2 genetics associated with coronavirus susceptibility

Variations in human ACE2 genetics associated with coronavirus susceptibility

Antidepressants may lower risk of death, complications in people with diabetes and depression

Antidepressants may lower risk of death, complications in people with diabetes and depression

Study reveals how non-alcoholic fatty liver disease can develop into a life-threatening complication

Study reveals how non-alcoholic fatty liver disease can develop into a life-threatening complication

Real-world evidence SARS-CoV-2 mRNA vaccines work and help prevent worst outcomes

Real-world evidence SARS-CoV-2 mRNA vaccines work and help prevent worst outcomes

New study revises current textbook knowledge about gastrulation

New study revises current textbook knowledge about gastrulation

Researchers reveal the role of hypothalamic astrocytes in obesity-related hypertension

Researchers reveal the role of hypothalamic astrocytes in obesity-related hypertension

Link between SARS-CoV-2 organotropism and kidney injury

Link between SARS-CoV-2 organotropism and kidney injury

Oral antidiabetic medication provides kidney protection in focal segmental glomerulosclerosis

Oral antidiabetic medication provides kidney protection in focal segmental glomerulosclerosis

COVID-19 can cause long-term consequences for the kidneys

COVID-19 can cause long-term consequences for the kidneys

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

Eating at least two servings of fruit per day reduces diabetes risk by 36%

Eating at least two servings of fruit per day reduces diabetes risk by 36%

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Long COVID patients at higher risk of small airway disease

Long COVID patients at higher risk of small airway disease

Glycosylated hemoglobin can provide a useful estimate of atherosclerosis and cardiovascular events

Glycosylated hemoglobin can provide a useful estimate of atherosclerosis and cardiovascular events

Study demonstrates the negative effects of HERV activation on human brain development

Study demonstrates the negative effects of HERV activation on human brain development

A study reports the first case of an upper extremity deep vein thrombosis (DVT) recurrence due to COVID-19 infection

A study reports the first case of an upper extremity deep vein thrombosis (DVT) recurrence due to COVID-19 infection

Study highlights the need for more personalized approach to measuring BMI

Study highlights the need for more personalized approach to measuring BMI

Black fungus complicates India's COVID pandemic

Black fungus complicates India's COVID pandemic

Spouse's history of heart disease may increase a person’s own cardiovascular risk

Spouse's history of heart disease may increase a person’s own cardiovascular risk

Study examines risk phenotypes of diabetes and their association with COVID-19 severity

Study examines risk phenotypes of diabetes and their association with COVID-19 severity