Diagnostic News and Research

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Enzyme Cdk1 may lead to new cancer therapies

With a four-year, $707,000 grant from the American Cancer Society, Yanchang Wang, assistant professor of biomedical sciences in the Florida State University College of Medicine, hopes to learn how a particular enzyme could possibly help put the brakes on the runaway cell division process that occurs in many forms of cancer.

27 Feb 2008

PolyTherics and Celtic Pharma sign agreement to explore technologies for improved drug performance

PolyTherics Limited, a biopharmaceutical spin-out company from Imperial College London and the London School of Pharmacy, and Celtic Pharma Development Services Bermuda Ltd, a subsidiary of Celtic Pharmaceutical Holdings LP, a global private equity investment fund focused on the biopharma industry, today announced that they have entered into a broad research collaboration agreement.

26 Feb 2008

Researchers isolate biomarkers in the blood that identify mood disorders

Indiana University School of Medicine researchers have isolated biomarkers in the blood that identify mood disorders, a breakthrough that may change the way bipolar illness is diagnosed and treated.

26 Feb 2008

Hormone therapy increases frequency of abnormal mammograms, breast biopsies

Combined hormone therapy appears to increase the risk that women will have abnormal mammograms and breast biopsies, and it may decrease the effectiveness of both methods for detecting breast cancer, according to a report in the Feb. 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

26 Feb 2008

Higher prevalence of stroke in the United States compared to Europe

American adults have a higher prevalence of stroke than their European counterparts, due in part to a higher rate of stroke risk factors among Americans and barriers to care in the United States, according to a study presented at the American Stroke Association's International Stroke Conference 2008.

26 Feb 2008

New chemical tool kit manipulates mitochondria, reveals insights into drug toxicity

Why do nearly 1 million people taking cholesterol-lowering statins often experience muscle cramps? Why is it that in the rare case when a diabetic takes medication for intestinal worms, his glucose levels improve? Is there any scientific basis for the purported health effects of green tea?

26 Feb 2008

New metabolic imaging instrument shows promise as screening device in diabetes and other major eye diseases

Scientists at the University of Michigan have shown that their new metabolic imaging instrument can accurately detect eye disease at a very early stage.

26 Feb 2008

Unusual case of upper obstructive syndrome

Aorto-duodenal fistulae (ADF) are the most frequent aorto-enteric fistulae (80%) and the most frequent presenting sign of ADF is upper gastrointestinal bleeding (UGI).

25 Feb 2008

A rare diagnosis in the operation room: Kidney atrophy due to duplicated colon in an adult

Gastrointestinal congenital anomalies are rare entities in an adult patient.

25 Feb 2008

Female-to-male transsexuals have higher androgen levels, not polycystic ovary syndrome

Contrary to previous studies, female-to-male transsexuals do not have a higher prevalence of polycystic ovary syndrome (PCOS), though they do have significantly higher androgen levels, according to a new study accepted for publication in the Journal of Clinical Endocrinology & Metabolism (JCEM).

21 Feb 2008

Computers are able to diagnose Alzheimer's disease faster and more accurately than experts

According to the Alzheimer's Research Trust, there are over 700,000 people currently living in the UK with dementia, of which Alzheimer's disease, a neurodegenerative disease, is the most common form.

21 Feb 2008

New method for detecting HER2 breast cancer

Generations of mothers have served up chicken soup to remedy the common cold, but now the therapeutic fowl may find use in diagnosis as well.

21 Feb 2008

Risk factors for Parkinson's disease focus of new research

A new study demonstrates that high levels of MAO-B, an enzyme that regulates nerve activity in the brain, cause Parkinson's-like symptoms in mice genetically engineered to overexpress the protein.

20 Feb 2008

Discovery of antibody that neutralizes two viruses classified as henipaviruses

In laboratory experiments, scientists at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), and their colleagues supported by the NIH National Institute of Allergy and Infectious Disease (NIAID), have discovered an antibody that neutralizes two viruses classified as henipaviruses.

18 Feb 2008

Identical twins are not genetically identical

This surprising finding is presented by American, Swedish, and Dutch scientists in a study being published today in the prestigious journal American Journal of Human Genetics.

17 Feb 2008

Slow growth rate found in overall prices in medical technology sector

AdvaMed, the Advanced Medical Technology Association, has released an important new study that demonstrates the slow rate in growth in overall prices in the highly competitive medical technology sector.

14 Feb 2008

Throwing money at back pain treatments does not guarantee relief

A new study by researchers in the United States has revealed that despite the billions of dollars spent in recent years on treating back pain, many people gain little relief.

13 Feb 2008

Prenatal exposure to maternal antibodies linked to autistic behaviors in offspring

New research from the UC Davis M.I.N.D. Institute shows that an interaction between fetal brain cells and maternal antibodies could be linked with the repetitive behavior - also called stereotypies - that is characteristic of autism.

12 Feb 2008

Is it safe delaying decision about having prostate cancer surgery?

Is it safe to wait to make a decision about having prostate cancer surgery, even after you've waited and waited for all the doctor appointments and test results? Or will the additional delay reduce your chances of being cured?

8 Feb 2008

New approach to genetic diagnosis in autism

A practical, stepwise approach to diagnosing genetic causes of autism and related disorders is proposed in the January issue of Genetics in Medicine, official journal of the American College of Medical Genetics (ACMG), published by Lippincott Williams & Wilkins.

7 Feb 2008