Digestive System News and Research

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Clinical utility of Caris Molecular Intelligence in five studies to be presented at ASCO 2015

Caris Life Sciences, a leading biotechnology company focused on fulfilling the promise of precision medicine, today announced the presentation of data from five studies that demonstrate the clinical utility of Caris Molecular Intelligence®, the company's panomic comprehensive tumor profiling service, in helping to identify targeted treatment options for patients with rare and/or aggressive tumors.

1 Jun 2015

Multiplatform biomarker analysis reveals new therapeutic options for squamous cell anal carcinomas

While squamous cell anal carcinomas are rare, representing only about 2% of digestive-system cancer diagnoses, these cancers, which are associated with the human papillomavirus (HPV), sometimes prove very difficult to treat, recurring or developing metastases following standard treatment.

30 May 2015

Overweight and inflammation during adolescence may increase colorectal cancer risk later in life

Being very overweight in your teens doubles the risk of developing colorectal cancer later in life compared to those whose weight was within the normal range a new Swedish study suggests. The research team behind the study are from örebro University in Sweden and Harvard School of Public Health in the US.

27 May 2015

New study reveals that 'imperfect drug penetration' can accelerate pathogens' resistance

Prescribing patients two or more drugs that do not reach the same parts of the body could accelerate a pathogen's resistance to all of the drugs being used in treatment, according to a new study published today in the Proceedings of the National Academy of Sciences.

19 May 2015

Simple blood tests diagnose irritable bowel syndrome quickly and accurately

Millions of people afflicted by irritable bowel syndrome can now be diagnosed quickly and accurately with two simple blood tests developed by a Cedars-Sinai gastroenterologist.

14 May 2015

Special issue of Gastroenterology highlights how food impacts health and disease

Patients are always interested in understanding what they should eat and how it will impact their health. Physicians are just as interested in advancing their understanding of the major health effects of foods and food-related diseases.

28 Apr 2015

Yale researchers successfully correct gene mutation that causes cystic fibrosis

Yale researchers successfully corrected the most common mutation in the gene that causes cystic fibrosis, a lethal genetic disorder. The study was published April 27 in Nature Communications.

28 Apr 2015

Understanding how nerve cells in the brain produce energy required to function

New research published today in the journal Nature Communications represents a potentially fundamental shift in our understanding of how nerve cells in the brain generate the energy needed to function. The study shows neurons are more independent than previously believed and this research has implications for a range of neurological disorders.

25 Apr 2015

May issues of AGA's journals highlight important research updates on liver disease

The May issues of AGA's journals -- Clinical Gastroenterology and Hepatology and Gastroenterology -- highlight important research updates on the most deadly forms of liver disease.

23 Apr 2015

New research could transform treatments for patients with Barrett's Oesophagus

New research from the University of Warwick and University Hospitals Coventry and Warwickshire NHS Trust could transform treatments and diagnosis for a common digestive condition which affects thousands of patients.

15 Apr 2015

Every third teenager reports one mental disorder, one chronic physical disease

Every third teenager has suffered from one mental disorder and one physical disease. These co-occurrences come in specific associations: More often than average, depression occurs together with diseases of the digestive system, eating disorders with seizures and anxiety disorders together with arthritis, heart disease as well as diseases of the digestives system.

9 Apr 2015

Breastfeeding is not a frontline strategy to prevent obesity, say researchers

A new study supports human milk as the optimal first food for babies, but the study raises questions about whether breast milk protects children from becoming obese.

7 Apr 2015

New AGA guideline changes clinical practice for patients with asymptomatic pancreatic cysts

A new guideline from the American Gastroenterological Association changes clinical practice by recommending longer surveillance periods for patients with asymptomatic pancreatic cysts and new criteria that limits surgery to those who will receive the most benefit.

25 Mar 2015

Using the butterfly effect to predict heart disease: an interview with Dr George and Dr Parthimos, Cardiff University

The emergence of the butterfly effect in many physical events reveals two fundamental laws that underpin all nonlinear systems. The first principle is known as determinism, which means that the evolution of an event can be followed accurately in the future, as long as we know its precise starting point and the rules of how a situation can change with time.

23 Mar 2015

Intestinal bacteria can cause type 2 diabetes in African American men

African American men at elevated risk for developing type 2 diabetes may have fewer beneficial and more harmful intestinal bacteria, according to research presented by University of Illinois at Chicago endocrinologist Dr. Irina Ciubotaru at the ENDO 2015 meeting in San Diego.

9 Mar 2015

Cancer Care Ontario raises awareness about colorectal cancer

March is Colorectal Cancer Awareness Month and Cancer Care Ontario (CCO) is on a mission to raise awareness about an organ that doesn't get the attention it deserves.

2 Mar 2015

Minihepcidin reverses iron overload of hemochromatosis, stops susceptibility to infections

Hemochromatosis (HH) is the most common genetic disorder in the western world, and yet is barely known. Only in the US 1 in 9 people carry the mutation (although not necessarily the disease).

2 Mar 2015

N30 Pharmaceuticals becomes Nivalis Therapeutics

N30 Pharmaceuticals, Inc., a clinical-stage pharmaceutical company focused on the development of product candidates for cystic fibrosis (CF), announced today that the Company has changed its name to Nivalis Therapeutics, Inc. The Company's lead product candidate, N91115, is a novel inhibitor of S-nitrosoglutathione reductase (GSNOR).

24 Feb 2015

Possible cause of liver disease identified in adolescents with cystic fibrosis

A professor at the University of Colorado School of Medicine at the Anschutz Medical Campus and his colleagues have found a possible cause of liver disease in adolescents with cystic fibrosis.

19 Feb 2015

New AGA guideline provides guidance to prevent HBV reactivation

Long-term immunosuppressive therapy can cause the hepatitis B virus (HBV) to become active, even in patients who are not aware that they are infected with the virus. A new guideline from the American Gastroenterological Association provides guidance to physicians and patients who use immunosuppressive agents for the treatment of a variety of disorders, including gastrointestinal, dermatologic, neurologic and rheumatologic, among others.

9 Feb 2015