Disease Modeling News and Research

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Scientists develop new model of coronavirus diffusion through a community

The coronavirus doesn't spread uniformly through a community.But in the world of disease modeling, many projections take a high-level approach to a geographic area, like a county or state, and forecast based on a general idea that a virus will take root and spread at an equal rate until it reaches its peak of infection.

30 Oct 2020

Tabba Heart Institute and IHME partner to improve cardiovascular health in Pakistan

Tabba Heart Institute and the Institute for Health Metrics and Evaluation at the University of Washington's School of Medicine are partnering to improve public knowledge and inform policymakers of cardiovascular health in Pakistan by collecting and sharing data, leveraging their expertise in health metrics sciences to provide more accurate estimates of the national and provincial burden of cardiovascular diseases in Pakistan.

28 Oct 2020

Adult stem cell-based lung organoid models emulate host immune response in fatal COVID-19

Recently, a team of researchers from the University of California San Diego and The Scripps Research Institute, CA, USA, showed that an integrated stem cell-based disease modeling and computational approach is crucial for simulating the host immune response in fatal COVID-19 patients.

19 Oct 2020

NIH provides $9.3 million grant to create new Center for Precision Animal Modeling at UAB

A new Center for Precision Animal Modeling, or C-PAM, has been created at the University of Alabama at Birmingham, supported by a five-year, $9.3 million grant from the National Institutes of Health's Office of Research Infrastructure Programs.

9 Oct 2020

Viral loads peak before symptom onset in COVID-19

By reviewing published literature on viral loads and viral shedding, researchers found that viral loads for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)peak before symptoms are seen. This has substantial implications for prevention strategies.

5 Oct 2020

NIH awards grants for using bioengineered models to improve clinical trial design

Clinical Trials on a Chip researchers plan to build and test common and rare disease models to help improve the clinical trial process.

30 Sep 2020

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Gruthan Bioscience, LLC, a Medical University of South Carolina startup based in Charleston, South Carolina, received a Small Business technology Transfer (STTR) award from the National Heart, Blood and Lung Institute in August to take the next step in developing a novel class of cholesterol-lowering drugs to treat familial hypercholesterolemia.

24 Sep 2020

Curi Bio Announces Mantarray™ Platform for Analysis of 3D Engineered Muscle Tissues for Discovery of New Therapeutics

Curi Bio today announced the Mantarray™ platform for human-relevant 3D engineered muscle tissue (EMT) analysis.

From Curi Bio 16 Sep 2020

Balancing COVID-19 risk with educational benefits in school reopening decisions

Now a new study by researchers at the Institute for Disease Modeling and published on the preprint server medRxiv* in September 2020 focuses on modeling the potential risk of COVID-19 for school students and staff if schools are re-opened in a range of scenarios. This could guide further research on the health and educational outcomes of school reopenings.

14 Sep 2020

New EU research project seeks to kickstart the development of "Organoid Cell Atlas"

HCA|Organoid is a new EU research project that combines single-cell profiling and organoid technology to validate organoids as faithful models of human biology.

31 Aug 2020

Inconsistent implementation of COVID-19 control has dire consequences

Researchers in the United States have conducted a study highlighting the potential unintended consequences of implementing coronavirus disease 2019 (COVID-19) control policies in an inconsistent, patchy manner.

25 Aug 2020

Researchers achieve bleeding-free anti-coagulation with synthetic inhibitor

Patients who suffer from thrombosis, pulmonary embolism or stroke are usually put on drugs that help their blood flow more smoothly through their body.

4 Aug 2020

Scientists develop human lung organoids to study SARS-CoV-2 infection

Now, a new study published on the preprint server bioRxiv in July 2020 reports the development of a human distal lung culture system that can be functionally tested. This will help not only to understand how this infection produces disease but also to test the proliferative capacity of the stem cells in this part of the body.

30 Jul 2020

NanoSurface Biomedical is now Curi Bio

NanoSurface Biomedical, a leading developer of human stem cell-based biotechnology products, today announced a comprehensive rebrand, including a change of the company’s name to Curi Bio.

From Curi Bio 15 Jul 2020

Fred Hutch joins new clinical trials network to fight COVID-19

Fred Hutchinson Cancer Research Center has been named the coordinating center for vaccine clinical trials of the COVID-19 Prevention Network.

8 Jul 2020

UMass Amherst biostatistician awarded federal grants to support research on pandemic forecasting

University of Massachusetts Amherst biostatistician Nicholas Reich has been awarded grants from the U.S. Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH) to support innovation and expansion in his groundbreaking pandemic forecasting work.

1 Jul 2020

SARS-CoV-2 can infect heart cells in a lab dish, study shows

A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.

30 Jun 2020

New model helps study human hippocampal neurons

Neuroscientists and stem cell researchers at Lund University in Sweden have developed a research model that allows studying human hippocampal neurons, the brain cells primarily affected by Alzheimer's disease pathology.

29 Jun 2020

Researchers use human stem cell models to analyze degeneration in glaucoma

More than 3 million Americans have glaucoma, a serious eye condition causing vision loss. Using human stem cell models, researchers at Indiana University School of Medicine found they could analyze deficits within cells damaged by glaucoma, with the potential to use this information to develop new strategies to slow the disease process.

11 Jun 2020

COVID-19 lockdowns estimated to have prevented 3 million deaths across 11 European countries

Now, a new study by researchers at Imperial College London estimates that lockdowns prevented around 3.1 million deaths in 11 European countries. The modeling study, published in the journal Nature, highlights that social distancing measures worked in reducing the spread of the virus.

10 Jun 2020