Diuretic Drug News and Research

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A diuretic is any drug that elevates the rate of urination and thus provides a means of forced diuresis. There are several categories of diuretics. All diuretics increase the excretion of water from bodies, although each class does so in a distinct way.

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

A study published recently in the journal Viruses has identified a potent diuretic ethacrynic acid as an efficient inhibitor of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This drug can be potentially repurposed to treat coronavirus disease 2019 (COVID-19).

20 Jan 2021

Diuretic drug may be just as effective as oral antibiotics to treat acne in female patients

In a finding that suggests the potential for practice change that would reduce the use of antibiotics in dermatology, researchers in the Perelman School of Medicine at the University of Pennsylvania have found the diuretic drug spironolactone may be just as effective as antibiotics for the treatment of women's acne.

4 Jun 2018

Study suggests potential new treatment for seizures

A study out today in the journal Nature Medicine suggests a potential new treatment for the seizures that often plague children with genetic metabolic disorders and individuals undergoing liver failure. The discovery hinges on a new understanding of the complex molecular chain reaction that occurs when the brain is exposed to too much ammonia.

17 Nov 2013

Gout: An Interview with Dr. Lawrence Edwards, Chairman and CEO of GUAES

Gout is the most common form of inflammatory arthritis that affects adults. It's a disease caused by the presence of uric acid crystals in and around the joints. It's a disease that's becoming more and more common. It probably has doubled in its prevalence worldwide over the past twenty to thirty years.

18 Sep 2013

Gout, uric acid levels and risk of death: an interview with Professor Austin Stack, Graduate Entry Medical School, University of Limerick

Gout is a relatively common arthritic disease that affects about 4% (I in 25) of the population. It results from the deposition of uric acid in joints due to elevated blood levels and a resulting inflammation ensues which is very painful.

26 Jul 2013

BMI may influence which blood pressure treatments work best

According to new research published Online First in The Lancet, body mass index (BMI) may influence which blood pressure medications work best at reducing the major complications of high blood pressure (strokes, heart attacks, and death).

7 Dec 2012

Why is the incidence of gout increasing?

Gout has been described by the Daily Mail as something, “usually associated with port-swilling, over-fed elderly men of the 19th century”. (1) Recent research carried out at the Boston University School of Medicine, however, has found that the incidence of gout in the US is on the rise. (2) Thus, the condition is clearly not something that only affects this stereotype.

17 Jul 2012

Aldosteronism linked to poor bone health

Primary aldosteronism is associated with low bone mass, increased prevalence of osteoporosis, and vertebral fractures, Italian research shows.

7 Jun 2012

Risk of gout flare-ups greatly increased by purine rich foods

Foods rich in purines, particularly those found in meat and seafood, quintuple the immediate risk of a gout flare-up, finds research published online in the Annals of the Rheumatic Diseases.

31 May 2012

Dehydration: how much should we drink per day?

As the northern hemisphere approaches the summer months, many of us begin to think about drinking more to prevent dehydration. But exactly how much should we be drinking a day? Does the amount vary depending on what we are drinking? And what happens if we don’t drink enough fluid?

30 May 2012

Researchers examine effects of antirejection drugs in kidney transplant patients

Modern medicine's ability to save lives through organ transplantation has been revolutionized by the development of drugs that prevent the human body from rejecting the transplanted organ.

10 Oct 2011

Diuretic lessens risk of death from mild heart failure: Study

A new study shows that diuretic pill Inspra (generic – Eplerenone) cuts down the risk of death and hospitalization among people with mild heart failure. The drug that is widely used to treat advanced heart failure, also has value for people with mild disease, says lead researcher Faiez Zannad, of Nancy University in Nancy, France. The results were reported at the American Heart Association's annual meeting and published simultaneously online in the New England Journal of Medicine.

16 Nov 2010

Academic detailing technique may help doctors follow treatment guidelines

Researchers often get frustrated when doctors fail to adopt treatment guidelines backed by the best evidence-based research.

3 Jun 2010

Risk factors of disordered eating in overweight youth identified

University of Minnesota Project Eating Among Teens (EAT) researchers have identified factors that may increase overweight adolescents' risk of engaging in extreme weight control behaviors such as self-induced vomiting, the use of diet pills, laxatives, and diuretics, as well as binge eating.

31 Jul 2009

Treatment blood pressure targets for hypertension

Aiming for lower than standard blood pressure targets offers no known clinical benefit, according to a Cochrane Review. In a systematic review of the evidence, researchers found that using antihypertensive drugs to reduce blood pressure below the 140/90 mm Hg standard was not associated with any reduction in death rates or serious morbidity.

7 Jul 2009

Diuretic drug works best at reducing risk of heart failure in hypertension

New research supports the findings of a landmark drug comparison study published in 2002 in which a diuretic drug or "water pill" outperformed other medications for high blood pressure. A scientific team including investigators from The University of Texas Health Science Center at Houston reports the findings in the May 11 issue of the Archives of Internal Medicine.

13 May 2009

Prevalence and physiological predictors of sleep apnea in patients with heart failure

Obstructive sleep apnea (OSA) and central sleep apnea (CSA) are not markedly decreased in heart failure (HF) patients managed with beta-blockers and spironolactone, reports a study in the March issue of Journal of Cardiac Failure, published by Elsevier.

6 May 2009

New system to check medication errors

Every day, pharmacists sidestep potential mix-ups while they're filling prescriptions-perhaps the doctor's scrawl is hard to decipher or sometimes the drug bottle is mistaken for another that looks awfully similar.

27 Apr 2009

Nile Therapeutics update on phase II CD-NP trial for acute heart failure

Nile Therapeutics, Inc. has announced that, in the course of reviewing the Investigational New Drug (IND) application materials that Nile submitted to the U.S. Food and Drug Administration (FDA) to support the initiation of the Company's Phase IIb clinical trial with CD-NP for the treatment of acute heart failure, the FDA has placed CD-NP on clinical hold.

30 Mar 2009

Licorice may offer a new approach to preventing colorectal cancer

A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report.

23 Mar 2009