Diverticulitis News and Research

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Diverticula are most common in the lower portion of the large intestine, called the sigmoid colon. When the pouches become inflamed, the condition is called diverticulitis. Ten to 25 percent of people with diverticulosis get diverticulitis. Diverticulosis and diverticulitis together are called diverticular disease.

Actavis reports positive results from ceftazidime-avibactam Phase III studies in cIAI patients

Actavis plc today confirmed positive topline results from RECLAIM-1 and -2, pivotal Phase III studies evaluating the potential for the investigational antibiotic, ceftazidime-avibactam as a treatment for adult hospitalized patients with complicated intra-abdominal infections.

19 Aug 2014

Pfizer reports positive results from two tofacitinib Phase 3 trials for moderate-to-severe plaque psoriasis

Pfizer Inc. announced today top-line results from two pivotal Phase 3 trials from the Oral treatment Psoriasis Trials (OPT) Program, OPT Pivotal #1 (A3921078) and OPT Pivotal #2 (A3921079), evaluating the efficacy and safety of tofacitinib, an oral Janus kinase (JAK) inhibitor, the first in a new class of medicines being investigated for the treatment of moderate-to-severe plaque psoriasis.

23 Apr 2014

FDA approves sNDA to include radiographic data updating label of Pfizer XELJANZ for treatment of RA

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) to update the current label of XELJANZ® (tofacitinib citrate) 5 mg tablets to include radiographic data from two Phase 3 studies, ORAL Scan (A3921044) and ORAL Start.

25 Feb 2014

New, "designer" dietary fiber may eliminate side effects of current IBS treatment

A newly-developed, "designer" dietary fiber with an added potential prebiotic effect may eliminate the side effects of current treatment for Irritable Bowel Syndrome which affects 10-20 percent of the population, disproportionately women.

20 Jan 2014

Studies offer new insight into diverticulosis

Diverticulosis, a condition that develops when pouches form in the wall of the colon, is increasing in frequency. It affects the majority of those reaching the age of 80 - a growing portion of the population - and imposes a substantial burden on health-care resources, but curiously there is a lack of data and unanswered questions around this condition.

18 Dec 2013

Research show that risk of diverticulosis is lower than previously thought

People who have diverticulosis, or pouches in the lining of the colon, often worry that they will eventually develop a painful and sometimes serious condition called diverticulitis, as previous research has shown that one in four, or up to 25 percent, of those with the condition will.

3 Dec 2013

People who consume nuts daily are 20% less likely to die

In the largest study of its kind, people who ate a daily handful of nuts were 20 percent less likely to die from any cause over a 30-year period than were those who didn't consume nuts, say scientists from Dana-Farber Cancer Institute, Brigham and Women's Hospital, and the Harvard School of Public Health.

21 Nov 2013

Smoking may increase risk of complications, death after colorectal procedures

Infection, pneumonia, blood clots and kidney failure are all possible complications after any major surgery. A new study shows that smoking boosts the risk of such complications following some of the most common colorectal procedures, including surgery for colon cancer, diverticulitis or inflammatory bowel disease.

25 Sep 2013

UCLA researchers explain Post-Diverticulitis Irritable Bowel Syndrome

UCLA researchers have described a new form of irritable bowel syndrome that occurs after an acute bout of diverticulitis, a finding that may help lead to better management of symptoms and relief for patients.

6 Sep 2013

TAP block procedure poses no significant risks to patients and cuts postoperative use of narcotics

Surgeons at University Hospitals Case Medical Center, Cleveland, are working to reduce serious complications that have been known to occur with colorectal operations.

29 Aug 2013

Bumping up appendicitis diagnostic accuracy

It is well worth emergency doctors asking patients with abdominal pain how they were affected by driving over speed bumps on their way to hospital, research suggests.

28 Dec 2012

Emergency diverticulitis surgery victim of the ‘weekend effect’

Patients who have emergency surgery at weekends for acute diverticulitis have worse outcomes than those admitted on weekdays, the results of a US study show.

2 Aug 2012

Top-line results from Shire's SPD476 phase 3 trial on diverticulitis

Shire plc, the global specialty biopharmaceutical company, today announced top-line results of the PREVENT2 trial, a phase 3 investigational study of once-daily SPD476, MMX mesalamine in patients with a history of diverticulitis.

31 Mar 2012

Basidiobolomycosis appears to be emerging in the Southwestern U.S.

An emerging fungal infection of the gastrointestinal tract that mimics cancer and inflammatory bowel disease appears to be emerging in the Southwestern United States and other desert regions, according to Mayo Clinic researchers in Arizona investigating the disease. The invasive fungus, Basidiobolus ranarum, is typically found in the soil, decaying organic matter and the gastrointestinal tracts of fish, reptiles, amphibians, and bats.

30 Mar 2012

Wake Forest Baptist researchers create emergency general surgery registry

Researchers at Wake Forest Baptist Medical Center in Winston-Salem, NC, have successfully created and implemented an emergency general surgery registry (EGSR) that will advance the science of acute surgical care by allowing surgeons to track and improve surgical patient outcomes, create performance metrics, conduct valid research and ensure quality care for all emergency general surgery (EGS) patients.

7 Feb 2012

Post-surgery death risk high among thinner people: Study

A new study has found that thinner people are at a higher risk of dying within 30 days of an operation than heavier people. The cause behind this trend is not clear.

22 Nov 2011

Racial disparities in emergency diverticulitis surgery

Black senior citizens who need surgery for the intestinal disorder diverticulitis are significantly more likely to die in the hospital than their equally ill white counterparts, even when each racial group carries the same health insurance, new Johns Hopkins research suggests.

22 Nov 2011

Complications from preventable surgical-site infections leading to hospital readmissions after colon surgery

Nearly one-quarter of privately insured colon surgery patients are readmitted to the hospital within three months of discharge at a cost of roughly $9,000 per readmission, according to Johns Hopkins researchers, who've identified a major area for quality improvement and cost reduction in health care.

17 Nov 2011

Global endoscopy equipment market to reach $33.7 billion by 2016: New report

By 2016 it is believed that the global endoscopy equipment market will be worth in excess of $33.7 billion, growing at a CAGR of 6.4% over the reporting period, according to a new report available on companiesandmarkets.com.

10 Aug 2011

Acute Care Emergency Surgical Service linked with 15% reduction in decision time

The use of Acute Care Emergency Surgical Service (ACCESS) in emergency departments (EDs) can lead to significant reductions in key patient measures, such as length of stay, surgical decision-making time and "time-to-stretcher", according to a study published in the August issue of the Journal of the American College of Surgeons.

9 Aug 2011