Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
Normal sleep depends on bacteria in the gut

Normal sleep depends on bacteria in the gut

Anti-diabetic drug could be repurposed for treating Parkinson's disease

Anti-diabetic drug could be repurposed for treating Parkinson's disease

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

Return of mice to home cage evokes significant rise in dopamine release, shows study

Return of mice to home cage evokes significant rise in dopamine release, shows study

Imaging technique reveals opioid receptor localization across the whole brain

Imaging technique reveals opioid receptor localization across the whole brain

Targeting TAAR5 can provide a new treatment opportunity for neurodegenerative disorders

Targeting TAAR5 can provide a new treatment opportunity for neurodegenerative disorders

Bioconductive, neuron-growing ink offers hope for people with nerve injury

Bioconductive, neuron-growing ink offers hope for people with nerve injury

Addictive drug displays different acute pharmacology and synaptic plasticity

Addictive drug displays different acute pharmacology and synaptic plasticity

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

Powerful drug used in chemotherapy could alleviate hallucinations in Parkinson's patients

Powerful drug used in chemotherapy could alleviate hallucinations in Parkinson's patients

Study examines the pharmacogenomics of opioid addiction

Study examines the pharmacogenomics of opioid addiction

Two well-known neurochemicals found to be involved in sub-second perception, cognition

Two well-known neurochemicals found to be involved in sub-second perception, cognition

Dopamine and serotonin play role in perception and decision-making

Dopamine and serotonin play role in perception and decision-making

Gene variations that regulate dopamine levels in the brain may influence mobility of elderly, frail adults

Gene variations that regulate dopamine levels in the brain may influence mobility of elderly, frail adults

Researchers elucidate the impact of genetic mutations in cocaine addiction

Researchers elucidate the impact of genetic mutations in cocaine addiction

Study demonstrates a proof-of-concept stem cell treatment in Parkinson's disease mouse model

Study demonstrates a proof-of-concept stem cell treatment in Parkinson's disease mouse model

Combination of alcohol and nicotine during pregnancy increases health risk in newborns

Combination of alcohol and nicotine during pregnancy increases health risk in newborns

'Silent' wave of neurological consequences may be on its way due to COVID-19

'Silent' wave of neurological consequences may be on its way due to COVID-19

Existence of brain-first and body-first Parkinson’s disease subtypes

Existence of brain-first and body-first Parkinson’s disease subtypes

A ferry protein in the pancreas safeguards beta-cells from high-fat diet induced stress

A ferry protein in the pancreas safeguards beta-cells from high-fat diet induced stress