Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
Dopamine D2 receptor modulates Wnt expression, controls cell proliferation

Dopamine D2 receptor modulates Wnt expression, controls cell proliferation

New technique enables the study of transporter proteins at a single-molecule level

New technique enables the study of transporter proteins at a single-molecule level

Chronic psychosocial adversity impairs dopamine production

Chronic psychosocial adversity impairs dopamine production

Depression in middle and older adulthood associated with nutrition

Depression in middle and older adulthood associated with nutrition

Scientists identify new mechanism for the development of Parkinson's disease

Scientists identify new mechanism for the development of Parkinson's disease

Parkinson's Foundation and Parkinson's UK form new partnership

Parkinson's Foundation and Parkinson's UK form new partnership

Future drugs aimed at halting cell-inactivation process may help prevent Parkinson's disease

Future drugs aimed at halting cell-inactivation process may help prevent Parkinson's disease

New study sheds light on how memories are formed

New study sheds light on how memories are formed

Does Parkinson's disease start in the brain or gut?

Does Parkinson's disease start in the brain or gut?

New way to slow and reverse fibrosis identified

New way to slow and reverse fibrosis identified

Brain function changes could help diagnose and manage depression

Brain function changes could help diagnose and manage depression

Discovery of causal link between hydrogen sulfide and schizophrenia

Discovery of causal link between hydrogen sulfide and schizophrenia

MPST enzyme levels in hair could be a good biomarker for schizophrenia

MPST enzyme levels in hair could be a good biomarker for schizophrenia

Detecting neurotransmitters at the lowest concentrations

Detecting neurotransmitters at the lowest concentrations

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

Long-term exposure to toxic chemicals in the environment impairs brain function in mice

Long-term exposure to toxic chemicals in the environment impairs brain function in mice

Fasting may increase motivation for exercise by surging "hunger hormone" ghrelin

Fasting may increase motivation for exercise by surging "hunger hormone" ghrelin

Does bipolar disorder increase the risk of Parkinson's disease?

Does bipolar disorder increase the risk of Parkinson's disease?

Researchers find behavioral, biological similarities between compulsive overeating and addiction

Researchers find behavioral, biological similarities between compulsive overeating and addiction

Scientists use patient-derived neurons to develop new treatment strategy for Parkinson's disease

Scientists use patient-derived neurons to develop new treatment strategy for Parkinson's disease