Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

SARS-CoV-2 infection could increase the risk of brain degeneration seen in Parkinson's disease

SARS-CoV-2 infection could increase the risk of brain degeneration seen in Parkinson's disease

Cannabidiol for Parkinson's disease symptom management

Cannabidiol for Parkinson's disease symptom management

Ultra-high strength 7T MRI scanner offers hope for treating cognitive symptoms in Parkinson’s patients

Ultra-high strength 7T MRI scanner offers hope for treating cognitive symptoms in Parkinson’s patients

Exercise increases dopamine signaling in the mouse brain

Exercise increases dopamine signaling in the mouse brain

Exercise increases levels of brain-derived neurotrophic factor which bolsters dopamine release

Exercise increases levels of brain-derived neurotrophic factor which bolsters dopamine release

New model provides a deep physiology-based explanation of how deep brain stimulation works

New model provides a deep physiology-based explanation of how deep brain stimulation works

New research reveals a potent weapon against Parkinson's disease

New research reveals a potent weapon against Parkinson's disease

Incorporating views of patients with Parkinson's disease in clinical research proven effective

Incorporating views of patients with Parkinson's disease in clinical research proven effective

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

Love is in the air...detected by PTR-TOF

Love is in the air...detected by PTR-TOF

Study finds brain circuit controlling drug withdrawal-induced anxiety and reinstatement

Study finds brain circuit controlling drug withdrawal-induced anxiety and reinstatement

Dopamine plays a significant role in recognizing human emotions, new study reveals

Dopamine plays a significant role in recognizing human emotions, new study reveals

New type of silver coating prevents bacteria from adhering to medical implants

New type of silver coating prevents bacteria from adhering to medical implants

Researchers identify 16 distinct cell populations in a key brain region for substance use disorders

Researchers identify 16 distinct cell populations in a key brain region for substance use disorders

Let’s Talk about Parkinson’s

Let’s Talk about Parkinson’s

New evidence on alterations of neuronal activity that drive food cravings during pregnancy

New evidence on alterations of neuronal activity that drive food cravings during pregnancy

Researchers discover potential link between inflammation and structure of specific brain regions

Researchers discover potential link between inflammation and structure of specific brain regions