Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
Ritalin drug affects organization of pathways that build brain networks used in attention, learning

Ritalin drug affects organization of pathways that build brain networks used in attention, learning

Study describes mechanism that makes people more vulnerable to hunger-causing stimuli

Study describes mechanism that makes people more vulnerable to hunger-causing stimuli

Research findings could help improve treatment of anxiety and post-traumatic stress disorders

Research findings could help improve treatment of anxiety and post-traumatic stress disorders

Study discovers link between meditation and how individuals respond to feedback

Study discovers link between meditation and how individuals respond to feedback

New study reveals yin-yang personality of dopamine

New study reveals yin-yang personality of dopamine

Study identifies new potential target for treating major common diseases

Study identifies new potential target for treating major common diseases

Antibodies: A Stable and Specific way to Target Cells in the Nervous System

Antibodies: A Stable and Specific way to Target Cells in the Nervous System

Study: The brain prioritizes high-reward events when preserving memories

Study: The brain prioritizes high-reward events when preserving memories

Human drugs alter cricket personality

Human drugs alter cricket personality

Inhibition of one protein clears toxic clumps seen in Parkinson's disease, study finds

Inhibition of one protein clears toxic clumps seen in Parkinson's disease, study finds

Stem cells transplanted for treatment of Parkinson’s disease

Stem cells transplanted for treatment of Parkinson’s disease

Study of gaze fixation in monkeys reveals role of dopamine neurons in response inhibition

Study of gaze fixation in monkeys reveals role of dopamine neurons in response inhibition

Predictive model could improve sepsis care

Predictive model could improve sepsis care

NIH increases funding through the BRAIN Initiative

NIH increases funding through the BRAIN Initiative

Dopamine neurons play role in reinforcing addictive effects of heroin

Dopamine neurons play role in reinforcing addictive effects of heroin

Study reveals safety, efficacy of brexpiprazole for schizophrenia patients with severe psychotic symptoms

Study reveals safety, efficacy of brexpiprazole for schizophrenia patients with severe psychotic symptoms

Alcohol changes the molecular basis of memory formation

Alcohol changes the molecular basis of memory formation

Kessler Foundation fellow receives award to explore behavioral patterns in children with ADHD

Kessler Foundation fellow receives award to explore behavioral patterns in children with ADHD

Cocaine overdoses on the rise with fentanyl combo flooding the market

Cocaine overdoses on the rise with fentanyl combo flooding the market

Scientists discover primary, direct target of alcohol in the brain

Scientists discover primary, direct target of alcohol in the brain