Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
Study implicates gut microbiome health in Parkinson's disease

Study implicates gut microbiome health in Parkinson's disease

New evidence on the links between immune activation and neuroinflammation and Parkinson's disease

New evidence on the links between immune activation and neuroinflammation and Parkinson's disease

Study implicates a specific type of brain cell as key player underlying the impact of stressors

Study implicates a specific type of brain cell as key player underlying the impact of stressors

Krill oil rewires global gene expression programs and promotes healthy aging

Krill oil rewires global gene expression programs and promotes healthy aging

Researchers identify potential lead compounds for the treatment of neuropsychiatric disorders

Researchers identify potential lead compounds for the treatment of neuropsychiatric disorders

Study examines how the dopamine system processes aversive unpleasant events

Study examines how the dopamine system processes aversive unpleasant events

Understanding the gut-brain connection in metabolic and neurological disorders

Understanding the gut-brain connection in metabolic and neurological disorders

OHSU discovery could suggest new avenues to treat symptoms of Parkinson's disease

OHSU discovery could suggest new avenues to treat symptoms of Parkinson's disease

Researchers unravel how the brain chemical dopamine relates to schizophrenia

Researchers unravel how the brain chemical dopamine relates to schizophrenia

Dangers of recreational/medical cannabis use

Dangers of recreational/medical cannabis use

Epigenetic changes related to Parkinson's disease are different in men and women, study says

Epigenetic changes related to Parkinson's disease are different in men and women, study says

High-sugar diet lowers the ability of the taste system to sense sweetness

High-sugar diet lowers the ability of the taste system to sense sweetness

Researchers identify brain cells responsible for shifts in the sleep-wake rhythm

Researchers identify brain cells responsible for shifts in the sleep-wake rhythm

New genetically based score could help identify young children at high risk of impulsive behavior

New genetically based score could help identify young children at high risk of impulsive behavior

Addiction experts fear the fallout if California legalizes sports betting

Addiction experts fear the fallout if California legalizes sports betting

Does leptin play a role in Parkinson’s disease?

Does leptin play a role in Parkinson’s disease?

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

Neurocomputational model could shed light on the development of cognitive abilities

Neurocomputational model could shed light on the development of cognitive abilities

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

Exercise hormone reduces protein levels linked to Parkinson's disease

Exercise hormone reduces protein levels linked to Parkinson's disease