Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
NIH starts clinical trial of drug to treat cravings associated with opioid use disorder

NIH starts clinical trial of drug to treat cravings associated with opioid use disorder

ADHD drug raising risk of psychosis

ADHD drug raising risk of psychosis

New drugs on PBS for Parkinson's, MND and Cutaneous T cell lymphoma

New drugs on PBS for Parkinson's, MND and Cutaneous T cell lymphoma

Roundworm study suggests alternatives for treatment of schizophrenia

Roundworm study suggests alternatives for treatment of schizophrenia

Researchers measure brain metabolite levels in people with mild memory problems

Researchers measure brain metabolite levels in people with mild memory problems

Scientists identify brain circuit responsible for cocaine-seeking behavior during relapse

Scientists identify brain circuit responsible for cocaine-seeking behavior during relapse

Study unravels how cancer medication works in brains of Parkinson's patients

Study unravels how cancer medication works in brains of Parkinson's patients

Parkinson's treatment boosts the number and strength of brain cell 'batteries'

Parkinson's treatment boosts the number and strength of brain cell 'batteries'

UCSF scientists develop new strategy for targeting key Parkinson's molecule

UCSF scientists develop new strategy for targeting key Parkinson's molecule

Study on REM sleep disorder patients provides key predictors of Parkinson's disease

Study on REM sleep disorder patients provides key predictors of Parkinson's disease

Young adults at risk of addiction show differences in important brain region

Young adults at risk of addiction show differences in important brain region

Stress controllability mitigates the negative effects

Stress controllability mitigates the negative effects

Experimental treatment offers hope to restore cells damaged in Parkinson's disease

Experimental treatment offers hope to restore cells damaged in Parkinson's disease

Pioneering trial offers hope for patients with Parkinson’s disease

Pioneering trial offers hope for patients with Parkinson’s disease

Pioneering clinical trials offers hope to restore damaged cells in Parkinson's disease

Pioneering clinical trials offers hope to restore damaged cells in Parkinson's disease

Neuroscientists reveal that simple brain region can guide complex feats of mental activity

Neuroscientists reveal that simple brain region can guide complex feats of mental activity

Researchers capture altered brain activity patterns of Parkinson's in mice

Researchers capture altered brain activity patterns of Parkinson's in mice

Study finds neuromelanin-sensitive MRI as potential biomarker for psychosis

Study finds neuromelanin-sensitive MRI as potential biomarker for psychosis

Newly developed stem cell technologies show promise for treating PD patients

Newly developed stem cell technologies show promise for treating PD patients

Researchers identify brain pathways of aversion

Researchers identify brain pathways of aversion