Doxorubicin News and Research

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Doxorubicin hydrochloride is approved for use with other drugs as adjuvant therapy for breast cancer that has spread to the lymph nodes, including cancer that is HER-2 positive or has spread after surgery.

In addition to the uses that have been approved by the FDA, doxorubicin hydrochloride is sometimes used alone or with other drugs to treat other types of cancer. The drug continues to be studied in the treatment of many types of cancer.

Study shows new approach to improve survival rates for patients with stage IV Wilms tumors

A new study showing significantly improved survival rates for patients with stage IV Wilms tumors with lung metastases was recently published in the Journal of Clinical Oncology.

26 Apr 2018

Nanodisc-delivered cancer treatment helps eliminate tumors

In the wrestling match with cancer, chemoimmunotherapy is the new strong arm, and it is building muscle with a nanodisc disguised as "good cholesterol."

18 Apr 2018

Adjuvant AC chemotherapy found to be effective in treating HRD-positive breast cancer patients

People with tough-to-treat triple negative breast cancer, whose tumors also don't allow for double-strand DNA repair, fare better when treated with a common adjuvant breast cancer chemotherapy combination, according to results from a SWOG clinical trial.

20 Mar 2018

IBN’s green tea-based drug nanocarriers show superior tumor-killing performance

The Institute of Bioengineering and Nanotechnology of A*STAR has reported superior results using new green tea-based nanocarriers to kill liver cancer cells, compared to existing drug delivery systems.

16 Mar 2018

Machine learning can help accurately predict clinical outcomes in patients with heart problems

Several studies being presented at the American College of Cardiology's 67th Annual Scientific Session demonstrate how the computer science technique known as machine learning can be used to accurately predict clinical outcomes in patients with known or potential heart problems.

1 Mar 2018

Breast cancer and lymphoma survivors at greater risk of developing heart failure

Patients who were treated for breast cancer or lymphoma are more than three times at risk for developing congestive heart failure, compared with patients who did not have cancer. Congestive heart failure is when the heart muscle does not pump blood as well as it should.

28 Feb 2018

Breast cancer patients may be at increased risk of cardiovascular diseases

Breast cancer patients may be at an increased risk of cardiovascular diseases including heart failure and may benefit from a treatment approach that weighs the benefits of specific therapies against potential damage to the heart, according to a new scientific statement from the American Heart Association published in its journal Circulation.

1 Feb 2018

Scientists find sperm as potential drug carrier to treat gynecological conditions

Delivering drugs specifically to cancer cells is one approach researchers are taking to minimize treatment side effects. Stem cells, bacteria and other carriers have been tested as tiny delivery vehicles.

20 Dec 2017

New cancer drug begins clinical trial in human patients with rare brain tumor

A drug that spurs cancer cells to self-destruct has been cleared for use in a clinical trial of patients with anaplastic astrocytoma, a rare malignant brain tumor, and glioblastoma multiforme, an aggressive late-stage cancer of the brain.

28 Nov 2017

Researchers propose new treatment strategy for colon cancer patients

Colorectal cancer is the fourth leading cause of cancer-related deaths worldwide. In a new study, researchers demonstrate for the first time that a previously uncharacterized protein is increased in colon cancer. The protein is immunoglobulin containing proline rich receptor-1 (IGPR-1) which was recently identified in the same laboratory as a cell adhesion molecule.

20 Sep 2017

Injecting plant-based nanoparticles and chemotherapy drug helps halt tumor progression in mice

Researchers from Case Western Reserve University School of Medicine in collaboration with researchers from Dartmouth Geisel School of Medicine and RWTH Aachen University have adapted virus particles- that normally infect potatoes- to serve as cancer drug delivery devices for mice.

28 Jun 2017

New cancer drug shows promise to treat leukemia in mouse models

Almost 6,000 new cases of acute lymphoblastic leukemia, or ALL, are expected to be diagnosed this year in the United States. The blood cancer can affect both children and adults.

9 Jun 2017

Immunotherapy combination offers new hope for women with early stage triple negative breast cancer

A Yale Cancer Center clinical trial combining the immune checkpoint inhibitor (durvalumab/MEDI4736) with chemotherapy as preoperative treatment for early stage triple negative breast cancer disclosed a 71% pathologic complete response to the combination treatment in the initial phase I trial.

2 Jun 2017

Men appear to have worse chemotherapy-induced cardiomyopathy than women, research shows

Men seem to have worse chemotherapy-induced cardiomyopathy than women despite receiving similar cancer treatments, according to research presented today at EuroCMR 2017.

25 May 2017

WSU scientists develop new approach to deliver therapeutics to tumors

For the first time, WSU researchers have demonstrated a way to deliver a drug to a tumor by attaching it to a blood cell. The innovation could let doctors target tumors with anticancer drugs that might otherwise damage healthy tissues.

16 May 2017

Study finds no clear benefit of stem-cell transplant for double-hit lymphoma patients in remission

Patients with double hit lymphoma (DHL) who undergo autologous stem-cell transplantation (autoSCT) after achieving remission are not more likely to remain in remission or live longer than patients who do not undergo autoSCT, according to a new analysis from the Perelman School of Medicine and the Abramson Cancer Center of the University of Pennsylvania.

15 May 2017

UAB symposium highlights use of tissue engineering to repair broken hearts

The third annual Cardiovascular Tissue Engineering Symposium met at the University of Alabama at Birmingham last month, a gathering of noted physicians and scientists who share the goal of creating new tissues and new knowledge that can prevent or repair heart disease and heart attacks.

9 May 2017