Doxorubicin News and Research

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Doxorubicin hydrochloride is approved for use with other drugs as adjuvant therapy for breast cancer that has spread to the lymph nodes, including cancer that is HER-2 positive or has spread after surgery.

In addition to the uses that have been approved by the FDA, doxorubicin hydrochloride is sometimes used alone or with other drugs to treat other types of cancer. The drug continues to be studied in the treatment of many types of cancer.

Nanoparticles release bursts of calcium to reverse multidrug resistance in tumor cells

Multidrug resistance (MDR) -- a process in which tumors become resistant to multiple medicines -- is the main cause of failure of cancer chemotherapy.

16 Oct 2020

Combination of peptides and antibiotics could be key to eliminating Leishmania parasites

A combination of peptides and antibiotics could be key to eliminating the parasite causing leishmaniasis and avoiding the toxicity to people and animals caused by current drugs.

16 Oct 2020

Combination of antibiotics and peptides could eliminate parasite-causing leishmaniasis

A combination of peptides and antibiotics could be key to eliminating the parasite causing leishmaniasis and avoiding the toxicity to people and animals caused by current drugs.

16 Oct 2020

Cancer chemotherapy changes the function of cells that repair heart injury

Cancer chemotherapy changes the function of cells that repair heart injury, researchers at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) discovered.

30 Sep 2020

Novel liver cancer treatment could shrink tumors in a mouse model

Hepatocellular carcinoma is a common liver cancer with poor prognosis. With symptoms not discovered until later stages, it is considered the most fatal malignant liver cancer worldwide.

10 Sep 2020

Brazilian red propolis contains substances with anti-cancer properties

Brazilian red propolis found in beehives along the coast and mangroves in the Northeast region contains two substances with anti-cancer properties. In laboratory tests, they considerably reduced the proliferation of ovarian, breast, and brain cancer cells

10 Sep 2020

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Hepatocellular carcinoma is a particularly stubborn form of cancer with few treatments and a high mortality rate.

8 Sep 2020

First clinical trial could become an effective way to deliver chemotherapy to abdominal cancer patients

City of Hope surgical researchers are the first in the nation to open a clinical trial that could one day become an effective way to deliver chemotherapy to abdominal cancer patients who currently have very few treatment options.

11 Aug 2020

Researchers discover dose threshold that improves delivery of cancer-fighting drugs into a tumor

University of Toronto Engineering researchers have discovered a dose threshold that greatly increases the delivery of cancer-fighting drugs into a tumor.

11 Aug 2020

Proximity of mutated cells guides the initiation of tumor

Scientists have revealed a key factor that influences whether malignant cells will grow to form a tumor, in a new study published today in eLife.

21 Jul 2020

Researchers develop new nano drug that kills triple-negative breast cancer cells

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells.

20 Jul 2020

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Researchers from the Moscow Institute of Physics and Technology and their colleagues from Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry and Prokhorov General Physics Institute of the Russian Academy of Sciences have developed a breakthrough technology to resolve a key problem that has prevented the introduction of novel drugs into clinical practice for decades.

17 Jul 2020

Study provides insights into molecular factories of bacterial natural products

The active agents of many drugs are natural products, so called because often only microorganisms are able to produce the complex structures.

6 Jul 2020

Overcoming leukemia treatment resistance with nanoparticle drug delivery system

UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug may be repurposed as a treatment for resurgent or chemotherapy-resistant leukemia.

18 Jun 2020

Study resolves contradictions surrounding p53 gene's role in pluripotent stem cell differentiation

The gene p53 is extremely important in cell biology and, hence, the world of cell replacement therapy. Its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the "tumor suppressor gene."

1 Jun 2020

Study compares cediranib plus olaparib and standard of care therapy for platinum-sensitive ovarian cancer

Results of the NRG Oncology phase III clinical trial NRG-GY004 indicated that the addition of the investigational agent cediranib to olaparib and standard platinum-based chemotherapy did not improve progression-free survival (PFS) outcomes for women with platinum-sensitive ovarian cancer; however, activity between the treatments was similar in patients.

30 May 2020

Researchers report a new way to stabilize liposomes

For decades, scientists have explored the use of liposomes –– hollow spheres made of lipid bilayers –– to deliver chemotherapy drugs to tumor cells.

20 May 2020

Harnessing the formation of natural killer–tumor cell immunological synapse to treat solid cancers

There are immune cells in our bodies that directly destroy infected or cancer cells - they are called natural killer cells. Recently, a POSTECH research team has developed an integrative cancer therapy using adoptive natural killer cell therapy and chemotherapy.

13 May 2020

Immunotherapy before surgery may help eradicate high-risk breast cancer

A new study led by Yale Cancer Center researchers shows women with high-risk HER2-negative breast cancer treated before surgery with immunotherapy, plus a PARP inhibitor with chemotherapy, have a higher rate of complete eradication of cancer from the breast and lymph nodes compared to chemotherapy alone.

28 Apr 2020

Graphene-based nanomedicine enables targeted cancer treatment at molecular level

"Three" kinds of regalia such as crown, orb, and sward are often necessary to be a high king for conquering the world. For fighting off cancerous diseases, what do we need? This "triple" chemical modified nanomaterial might be save the patient.

23 Apr 2020

Doxorubicin News and Research

Nanoparticles release bursts of calcium to reverse multidrug resistance in tumor cells

Combination of peptides and antibiotics could be key to eliminating Leishmania parasites

Combination of antibiotics and peptides could eliminate parasite-causing leishmaniasis

Cancer chemotherapy changes the function of cells that repair heart injury

Novel liver cancer treatment could shrink tumors in a mouse model

Brazilian red propolis contains substances with anti-cancer properties

Combination of gas embolization and chemotherapy can lead to complete tumor regression

First clinical trial could become an effective way to deliver chemotherapy to abdominal cancer patients

Researchers discover dose threshold that improves delivery of cancer-fighting drugs into a tumor

Proximity of mutated cells guides the initiation of tumor

Researchers develop new nano drug that kills triple-negative breast cancer cells

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Study provides insights into molecular factories of bacterial natural products

Overcoming leukemia treatment resistance with nanoparticle drug delivery system

Study resolves contradictions surrounding p53 gene's role in pluripotent stem cell differentiation

Study compares cediranib plus olaparib and standard of care therapy for platinum-sensitive ovarian cancer

Researchers report a new way to stabilize liposomes

Harnessing the formation of natural killer–tumor cell immunological synapse to treat solid cancers

Immunotherapy before surgery may help eradicate high-risk breast cancer

Graphene-based nanomedicine enables targeted cancer treatment at molecular level

ACROBiosystems and the Fight Against COVID-19

Monoclonal Antibody Development and Characterization

Eliminating the Cold Chain with COVID-19 Molecular Transport Media

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