Doxorubicin News and Research

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Doxorubicin hydrochloride is approved for use with other drugs as adjuvant therapy for breast cancer that has spread to the lymph nodes, including cancer that is HER-2 positive or has spread after surgery.

In addition to the uses that have been approved by the FDA, doxorubicin hydrochloride is sometimes used alone or with other drugs to treat other types of cancer. The drug continues to be studied in the treatment of many types of cancer.

Childhood cancer treatment linked to higher breast cancer risk

Women who have been treated for cancer as a child with a certain type of chemotherapy have an increased risk of breast cancer, according to a large-scale international study of survivors of childhood cancer led by scientists from the Princess Máxima Center for pediatric oncology.

11 Sep 2023

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

A cell contains many specialized subunits, called organelles, that carry out important tasks such as energy generation, protein synthesis, and calcium outflux. But what happens when something goes wrong with one of the organelles?

31 Aug 2023

Nanotechnology's triple threat: Advancing precision cancer treatment

The design of tumor tissue-, cell-, and organelle-targeted cancer nanomedicines.

9 Aug 2023

High BMI increases risk of cardiotoxicity in breast cancer patients, study finds

Breast cancer survival rates have improved considerably in the last few decades in Colombia, but factors that increase the likelihood of patients experiencing cardiovascular side effects, like cardiotoxicity, are not well-known or well-treated.

2 Aug 2023

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes: implications for precision medicine

A recent study elucidated the molecular mechanisms of drug-induced regulation of growth differentiation factor 15 (GDF15).

1 Aug 2023

Research paves the way to safer, more effective treatment for children with aggressive blood cancers

Australian nanomedicine researchers have come up with a new approach to solving a decades-old clinical problem: getting treatment drugs to act selectively on cancer cells in the body.

18 May 2023

A new platform for testing cancer drug toxicity

For people with cancer, chemotherapy saves lives, but for some patients, the treatment comes with a side effect—heart damage.

25 Apr 2023

Chemists discover novel, highly effective anticancer agents with tridimensional structures

A research team co-led by chemists from City University of Hong Kong recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity and the ability to overcome drug resistance in cancer cells.

7 Apr 2023

Avacta appoints Karen Harrison as Chief Operating Officer for Therapeutics Division

Avacta Group plc today announced the appointment of Karen Harrison as Chief Operating Officer of its Therapeutics Division.

From Avacta Life Sciences Ltd. 28 Mar 2023

Upgraded tumor model points the way toward more effective cancer therapies

Tumor cells won't show their true selves in a petri dish, isolated from other cells.

20 Mar 2023

UK oncologists and cardiologists collaborate to prevent chemo-induced cardiomyopathy in cancer patients

Ever since she was 12 years old, Barbie Johnson has been a Kentucky girl at heart. Raised in the bluegrass, Barbie has worked at UK HealthCare for 18 years, first in gynecologic oncology and now in surgery scheduling.

26 Jan 2023

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome -; a cell's complete set of DNA -; is most vulnerable while it is being duplicated before a cell divides. Cancer cells constantly are dividing, so their genomes are constantly in jeopardy.

24 Jan 2023

Doxorubicin News and Research

Childhood cancer treatment linked to higher breast cancer risk

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

Nanotechnology's triple threat: Advancing precision cancer treatment

High BMI increases risk of cardiotoxicity in breast cancer patients, study finds

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes: implications for precision medicine

Research paves the way to safer, more effective treatment for children with aggressive blood cancers

A new platform for testing cancer drug toxicity

Chemists discover novel, highly effective anticancer agents with tridimensional structures

Avacta appoints Karen Harrison as Chief Operating Officer for Therapeutics Division

Upgraded tumor model points the way toward more effective cancer therapies

UK oncologists and cardiologists collaborate to prevent chemo-induced cardiomyopathy in cancer patients

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

DNA sequencing method detects where and how small molecule drugs interact with the targeted genome

Rare protein variant may hold the key to boosting effectiveness of breast cancer treatment

Researchers discover a protein linked with the onset of anthracycline-associated cardiac toxicity

IU researchers uncover new ways to prevent serious side effects for breast cancer patients

Scientists map neural pathways that lead to vomiting after eating contaminated food

Investigating the role of the gut-to-brain axis in defensive responses

Molecular drug transporters could improve treatment of cancers and other diseases

Penn State researchers lay the foundation for precision fabrication of tumor models

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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