Drug Abuse News and Research

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Cracking the code of adolecent drug use

A University of Sydney researcher has won a grant to study how exposure to drugs during adolescence affects the brain and behaviour.

23 Oct 2008

Could brain abnormality predict drug addiction?

Scientists at The University of Nottingham are to use MRI technology to discover whether abnormalities in the decision-making part of the brain could make some people more likely to become addicted to drugs.

22 Oct 2008

Couples with children with ADHD at risk of higher divorce rates, shorter marriages

Parents of a child with attention deficit hyperactivity disorder (ADHD) are nearly twice as likely to divorce by the time the child is 8 years old than parents of children without ADHD, the first study to look at this issue in depth has shown.

21 Oct 2008

Methamphetamine enters brain quickly and lingers

Using positron emission tomography (PET) to track tracer doses of methamphetamine in humans' brains, scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory find that the addictive and long-lasting effects of this increasingly prevalent drug can be explained in part by its pharmacokinetics - the rate at which it enters and clears the brain, and its distribution.

13 Oct 2008

Don't ask, don't tell doesn't work in prenatal care

While obstetrical care providers are doing a good job working with their patients on smoking cessation, they are not doing as well on abuse of other substances that can harm a woman's unborn baby. A new study appearing in the September 2008 issue of the journal Patient Education and Counseling reports that patients don't volunteer information about substance abuse unless specifically queried.

30 Sep 2008

Genetic screening effective for initial HIV treatment

A major study from a team of researchers from Weill Cornell Medical College and Massachusetts General Hospital has found that a recent change to HIV-treatment guidelines recommending genetic screening is cost-effective under certain conditions. The new recommendation suggests conducting a genetic screening test prior to prescribing the drug abacavir, one of the preferred first-line drugs for the treatment for HIV-infected adults.

17 Sep 2008

Neuroscientists discover a critical early step of memory formation

Researchers at the Johns Hopkins University School of Medicine report in the July issue of Neuron how nerve cells in the brain ensure that Arc, a protein critical for memory formation, is made instantly after nerve stimulation. Paradoxically, its manufacture involves two other proteins - including one linked to mental retardation - that typically prevent proteins from being made.

14 Sep 2008

Abuse of painkillers can predispose adolescents to lifelong addiction

No child aspires to a lifetime of addiction. But their brains might. In new research to appear online in the journal Neuropsychopharmacology today, Rockefeller University researchers reveal that adolescent brains exposed to the painkiller OxyContin can sustain lifelong and permanent changes in their reward system - changes that increase the drug's euphoric properties and make such adolescents more vulnerable to the drug's effects later in adulthood.

10 Sep 2008

The power of cigarettes not just down to nicotine

According to new research from the U.S., it may not just be nicotine which gives cigarettes their power but rather how it enhances other experiences.

4 Sep 2008

Sri Lankan health official says strong family bonds, values responsible for low prevalence of HIV/AIDS in country

Supportive family values and strong family bonds, in addition to the practice of monogamy, have contributed to the low prevalence of HIV/AIDS in Sri Lanka, Health Care and Nutrition Minister Nimal Siripala De Silva said recently at the second Asia Pacific Regional Meeting on universal access to HIV prevention in the Philippines, Sri Lanka's Daily News reports.

2 Sep 2008

Low levels of 'brain derived neurotrophic factor' may lead to obesity

A brain chemical that plays a role in long term memory also appears to be involved in regulating how much people eat and their likelihood of becoming obese, according to a National Institutes of Health study of a rare genetic condition.

28 Aug 2008

UT Southwestern discovery may lead to new drug-abuse treatments

Increased connections among brain cells caused by excessive drug use may represent the body's defense mechanism to combat addiction and related behaviors, scientists at UT Southwestern Medical Center have found.

27 Aug 2008

Addiction drug Vigabatrin proves successful in animal weight loss study

Vigabatrin, a medication proposed as a potential treatment for drug addiction by scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, also leads to rapid weight loss and reduced food intake according to a new animal study from the same research group.

20 Aug 2008

One night without sleep increases chemical dopamine in the human brain

Because drugs that increase dopamine, like amphetamines, promote wakefulness, the findings offer a potential mechanism explaining how the brain helps people stay awake despite the urge to sleep. However, the study also shows that the increase in dopamine cannot compensate for the cognitive deficits caused by sleep deprivation.

19 Aug 2008

Medicinal cannabis effective for neuropathic pain in HIV

In a double-blind, placebo-controlled clinical trial to assess the impact of smoked medical cannabis, or marijuana, on the neuropathic pain associated with HIV, researchers at the University of California, San Diego School of Medicine found that reported pain relief was greater with cannabis than with a placebo.

6 Aug 2008

Highly active antiretroviral therapy (HAART) equally effective in patients with or without history of injection drug use

Highly active antiretroviral therapy (HAART) has been extremely effective at slowing the progression of HIV infection to AIDS as well as extending the lives and improving the quality of life for those with HIV. However, some doctors have been reluctant to prescribe HAART to HIV-infected injection drug users because of concern that they may not fully benefit from the therapy.

6 Aug 2008

Fatal flaws in the way new drugs are tested and marketed

Americans are likely to be exposed to unacceptable side effects of FDA-approved drugs such as Vioxx in the future because of fatal flaws in the way new drugs are tested and marketed, according to research to be presented at the annual meeting of the American Sociological Association (ASA).

3 Aug 2008

Drug use by Europe's youth leads to risky sexual behaviour

High levels of alcohol and drug consumption by young people in Europe is leading to an increase in unsafe sexual practices and a consequent rise in sexually-transmitted disease infections, according to a recently published study by the European Institute of Studies on Prevention (IREFREA).

31 Jul 2008

Study sheds light on why addiction is a chronic disease

Drug addiction dramatically shifts a person's attention, priorities, and behaviors towards a focus almost entirely on seeking out and taking drugs. Now, an animal study funded by the National Institute on Drug Abuse, part of the National Institutes of Health, has identified some of the specific long-term adaptations in the brain's reward system that may contribute to this shift.

31 Jul 2008

How anti-depressants and cocaine interact with brain

In a first, scientists from Weill Cornell Medical College and Columbia University Medical Center have described the specifics of how brain cells process antidepressant drugs, cocaine and amphetamines. These novel findings could prove useful in the development of more targeted medication therapies for a host of psychiatric diseases, most notably in the area of addiction.

28 Jul 2008