Drug Delivery News and Research

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Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.

New approach to send ‘friendly’ nano-particles into the body shows promising results

A new approach to send ‘friendly’ nano-particles into a patient’s blood stream has shown promising results by modifying the surface of these potential drug, vaccine or cancer treatment delivery objects to encourage the best result.

14 Mar 2022

COVID-19 and the life sciences; what have we learned and where are we going?

News-Medical attended the 2022 SLAS press briefing where Peter Simpson, Michael Girardi, and Simon Meffan-Main gave their thoughts on the life sciences sector post-COVID-19.

From Society for Laboratory Automation and Screening (SLAS) 4 Mar 2022

New type of drug delivery vehicle mimics the properties of a red blood cell

From the liver to the kidneys to the lungs, the human body is equipped with many levels of filters, which protect the body from harmful outside materials. But this system also has its downsides. Critically important drugs such as chemotherapy or multiple sclerosis treatments are also foreign materials, so the body filters out a large portion of these drugs – up to 90%, in some cases.

2 Mar 2022

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Researchers at the Tufts University School of Engineering are building a reputation for precision targeting in drug delivery.

23 Feb 2022

Developing nanoplatforms for direct drug delivery to T cells

T cells, also known as lymphocytes, have important roles in various immune reactions. However, there are only a few reports on delivery systems into T cells. Realizing this, it is essential to work and actively contribute in controlling immune systems.

16 Feb 2022

New multiple-shot electroporation device could enable low-cost, effective cancer drug delivery

Researchers from the Singapore University of Technology and Design (SUTD) have developed a microsize-gap multiple-shot electroporation (M2E) device that could improve the effectiveness of delivering cancer drugs at a lower cost, globally.

12 Feb 2022

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

A study in mice -; led by researchers at Washington University School of Medicine in St. Louis -; shows that a new class of compounds the scientists developed can improve multiple aspects of metabolic syndrome.

12 Feb 2022

Understanding how COVID-19 infection spreads from the upper airways to the lungs

Whether COVID-19 becomes a life-threatening disease depends, in part, on the virus reaching one's lungs. Scientists suspect the initial infected tissues in the upper airway can act as the source for virus-laden droplets or boluses, that are aspirated into the lungs.

4 Feb 2022

Researchers receive $2,664,522 NIH award to improve long-term functionality of vascular grafts

A graft can be a life-saving device for coronary heart disease, which remains the leading cause of death for both men and women in the United States. However, at small diameters -; such as the coronary artery in the heart -; long-term graft failure rates are often higher than 40 percent.

2 Feb 2022

Novel approach to improve intranasal sprays used to treat respiratory viral infections

Researchers proposed a novel approach to improve intranasal sprays used to treat respiratory viral infections, including SARS-CoV-2 infections.

2 Feb 2022

Nanomedicine can be improved with proper and more predictive in vitro assays

Messenger RNA (mRNA) vaccines are a prime example of the promising field of nanomedicine. But progress in the design and application of nanoparticles as efficient delivery vehicles for biopharmaceutics containing nucleic acid or protein drug substances is, unfortunately, remarkably slow.

1 Feb 2022

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Neural stem cells (NSCs) engineered by Northwestern Medicine investigators used in combination with the HER2 inhibitor drug tucatinib improved survival in mice with HER2-positive breast cancer brain metastases, according to findings published in Proceedings of the National Academy of Sciences.

1 Feb 2022

New approach to make RNA vaccines easier to swallow

Like most vaccines, RNA vaccines have to be injected, which can be an obstacle for people who fear needles. Now, a team of MIT researchers has developed a way to deliver RNA in a capsule that can be swallowed, which they hope could help make people more receptive to them.

31 Jan 2022

Combined strategy suppresses the growth of deadly brain tumor

Short bursts of radiation therapy dramatically enhanced the efficiency of targeting glioblastomas with natural nanoparticle-based immunotherapy, thus suppressing growth of the deadly tumor, inducing anti-tumor immunity and prolonging survival in animal models, a research team at Massachusetts General Hospital has discovered.

31 Jan 2022

Scientists assemble carbon nanotubes in a new way to deliver cancer drugs

Fundamental science often finds applications beyond its original focus. Previously, scientists found applications for small diameter carbon nanotube porins in energy technology.

29 Jan 2022

Macromolecular gel with therapeutic payload could halt or slow post-traumatic osteoarthritis

Osteoarthritis affects over 32 million Americans, levying a huge cost on society. Unfortunately, other than analgesics, no pharmaceutical therapy exists that can slow or halt disease progression of a major subset of OA: post-traumatic osteoarthritis (PTOA).

26 Jan 2022

Scientists develop new drug delivery system for treating genetic diseases

A team of researchers led by Harvard and Broad Institute scientists has developed a new drug delivery system using engineered DNA-free virus-like particles (eVLPs) to package and deliver therapeutic levels of gene-editing proteins to animal models of disease.

22 Jan 2022

Drug Delivery News and Research

Further Reading

New approach to send ‘friendly’ nano-particles into the body shows promising results

COVID-19 and the life sciences; what have we learned and where are we going?

New type of drug delivery vehicle mimics the properties of a red blood cell

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Developing nanoplatforms for direct drug delivery to T cells

New multiple-shot electroporation device could enable low-cost, effective cancer drug delivery

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

Understanding how COVID-19 infection spreads from the upper airways to the lungs

Researchers receive $2,664,522 NIH award to improve long-term functionality of vascular grafts

Novel approach to improve intranasal sprays used to treat respiratory viral infections

Nanomedicine can be improved with proper and more predictive in vitro assays

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

New approach to make RNA vaccines easier to swallow

Combined strategy suppresses the growth of deadly brain tumor

Scientists assemble carbon nanotubes in a new way to deliver cancer drugs

Macromolecular gel with therapeutic payload could halt or slow post-traumatic osteoarthritis

Scientists develop new drug delivery system for treating genetic diseases

Laser-driven needle-free injection is more effective and safer than previous technologies

Virus-like particles as delivery vehicles for gene-editing

Therapeutic in vivo synthetic chemistry used to make anticancer drugs

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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