Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Andrew Buchanan on the Future of Biologics and AI

10 Nov 2023

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Mark Abbott, the Managing Director of Peak Proteins, about protein science and its significance in drug discovery.

10 Nov 2023

Open-science drug discovery campaign yields a wealth of data on SARS-CoV-2 main protease

Although the group's work has been freely available since its inception in March 2020, the COVID Moonshot Consortium is finally formally reporting their results.

9 Nov 2023

MD Anderson Cancer launches Institute for Data Science in to transform cancer care and research

The University of Texas MD Anderson Cancer Center today announced the launch of its Institute for Data Science in Oncology (IDSO), which integrates the most advanced computational and data science approaches with the institution's extensive scientific and clinical expertise to significantly improve patient's lives by transforming cancer care and research.

9 Nov 2023

COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

The work of the COVID Moonshot Consortium is being published in the prestigious journal Science on 10 November, revealing their discovery of a potent SARS-CoV-2 antiviral lead compound.

9 Nov 2023

New drug shows exciting promise for the treatment of ALS

In science, a simple but thorough observation can kick-start the most surprising findings. Researchers at the Hollings Cancer Center at the Medical University of South Carolina noticed that mice lacking a protein of interest in cancer research were showing visible signs of abnormal motor functions as they aged, including loss of coordination and strength.

8 Nov 2023

Industry & academia combine to support synthesis of squaric acid monoamides as building blocks for drug discovery

Asynt have collaborated with Kingston University and Key Organics to develop an accessible new synthetic compound library.

From Asynt 5 Nov 2023

WFIRM announces successful renewal of its Research Experiences for Undergraduates Site grant

The Wake Forest Institute for Regenerative Medicine (WFIRM) is thrilled to announce the successful renewal of its Research Experiences for Undergraduates (REU) Site grant from the National Science Foundation (NSF).

3 Nov 2023

Clinical trial demonstrates the effectiveness of ALS drug in treating people with acute spinal cord injuries

A small clinical trial with a pharmacokinetic sub-study, led by a world-renowned pharmacologist at the University of Houston, has demonstrated the promising effectiveness of the drug Riluzole for improving functionality in people with acute spinal cord injuries (SCI) if the drug is taken within 12 hours post-injury.

1 Nov 2023

The development of a machine-learned scoring function of human preference in the context of early drug discovery campaigns

In a recent study published in Nature Communications, researchers developed a scoring mechanism based on artificial intelligence for early drug discovery campaigns that might be utilized for compound prioritizing, motif rationalization, and biased drug design.

1 Nov 2023

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

In this interview, Jordi Carreras delves into the fascinating world of Cell Painting, a powerful technology gaining momentum in drug discovery. He shares insights into his groundbreaking research, the unique aspects of Phenaros' drug discovery platform, and the synergy between academia and industry.

From ELRIG (UK) Ltd. 1 Nov 2023

How next-gen sequencing is changing antibody drug discovery

New study outlines how next-generation sequencing (NGS) and machine-learning methods can revolutionize antibody discovery, particularly against SARS-CoV-2. The research demonstrates that NGS provides greater epitopic and paratopic diversity, enabling more effective identification and prioritization of therapeutic antibodies.

31 Oct 2023

Axon Biology & The Future of Drug Discovery: A Deep Dive with Dr Federico Dajas-Bailador

News-Medical sits down with Dr. Federico Dajas-Bailador, a leading expert in axon biology and drug discovery.

From ELRIG (UK) Ltd. 31 Oct 2023

UQ's drug discovery facility opens to researchers nationwide after $1.9M funding injection

The University of Queensland's small molecule drug discovery facility will open its doors to researchers from across Australia for the first time thanks to a National Collaborative Research Infrastructure Strategy (NCRIS) funding injection.

30 Oct 2023

AI-designed drug candidate shows promise for gastric acid inhibition

Researchers at Nagoya University in Japan created and improved artificial intelligence (AI) designs to synthesize a candidate compound for a new gastric acid inhibitor with a better binding affinity than existing drugs.

26 Oct 2023

New study challenges long-held belief about how chemotherapy works

A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and doctors have long misunderstood how some of the most common cancer drugs actually ward off tumors.

26 Oct 2023

Stanford chemists uncover new pathway for protein degradation, opening door to new therapeutics

When targeting problem proteins involved in causing or spreading disease, a drug will often clog up a protein's active site so it can't function and wreak havoc.

25 Oct 2023

Optibrium introduces cloud-based version of StarDrop drug discovery platform

Optibrium announced that its drug discovery platform, StarDrop.

From Optibrium Ltd. 23 Oct 2023

Pioneering partnership supports early-stage innovation against antimicrobial resistance to save lives

Innovate UK, LifeArc, and Medicines Discovery Catapult (MDC) have joined forces to create PACE (Pathways to Antimicrobial Clinical Efficacy), a £30 million initiative supporting early-stage innovation against antimicrobial resistance (AMR) to save lives. PACE has today (19 October 2023) announced its first funding call with up to £10 million available to support innovators developing new antimicrobials.

20 Oct 2023

MuTaLig: A multi-target paradigm for innovative drug discoveries

Everyone at some point in their life may need to take medication to treat an illness or disease. By finding new and better ways to create drugs, the COST Action Multi-target paradigm for innovative ligand identification in the drug discovery process (MuTaLig) helped improve the effectiveness and safety of the medications, which can ultimately benefit people's health and well-being.

19 Oct 2023

Drug Discovery News and Research

Further Reading

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

Open-science drug discovery campaign yields a wealth of data on SARS-CoV-2 main protease

MD Anderson Cancer launches Institute for Data Science in to transform cancer care and research

COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

New drug shows exciting promise for the treatment of ALS

Industry & academia combine to support synthesis of squaric acid monoamides as building blocks for drug discovery

WFIRM announces successful renewal of its Research Experiences for Undergraduates Site grant

Clinical trial demonstrates the effectiveness of ALS drug in treating people with acute spinal cord injuries

The development of a machine-learned scoring function of human preference in the context of early drug discovery campaigns

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

How next-gen sequencing is changing antibody drug discovery

Axon Biology & The Future of Drug Discovery: A Deep Dive with Dr Federico Dajas-Bailador

UQ's drug discovery facility opens to researchers nationwide after $1.9M funding injection

AI-designed drug candidate shows promise for gastric acid inhibition

New study challenges long-held belief about how chemotherapy works

Stanford chemists uncover new pathway for protein degradation, opening door to new therapeutics

Optibrium introduces cloud-based version of StarDrop drug discovery platform

Pioneering partnership supports early-stage innovation against antimicrobial resistance to save lives

MuTaLig: A multi-target paradigm for innovative drug discoveries

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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