Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

Scientist proposes geroprotective strategies to reduce lethality of COVID-19 in the elderly

Scientist proposes geroprotective strategies to reduce lethality of COVID-19 in the elderly

Using marine natural product to inhibit cervical cancer

Using marine natural product to inhibit cervical cancer

Horizon Discovery expands cell-based CRISPR screening services

Horizon Discovery expands cell-based CRISPR screening services

IRB Barcelona and Amazon join forces to develop computational tool in the fight against COVID-19

IRB Barcelona and Amazon join forces to develop computational tool in the fight against COVID-19

Investigating Human Disease with Mass Spectrometry-based Proteomics

Investigating Human Disease with Mass Spectrometry-based Proteomics

Excess cardiac myosin worsens damage to heart tissue during a heart attack

Excess cardiac myosin worsens damage to heart tissue during a heart attack

New microfluidic chip can mimic hypoxic conditions after a heart attack

New microfluidic chip can mimic hypoxic conditions after a heart attack

FDA approves immune-modulating therapy for treatment of multiple sclerosis

FDA approves immune-modulating therapy for treatment of multiple sclerosis

Why Primary Cells Are Important for In Vitro ADME-Tox Studies

Why Primary Cells Are Important for In Vitro ADME-Tox Studies

Gero uses AI platform to identify potential anti-COVID-19 drugs

Gero uses AI platform to identify potential anti-COVID-19 drugs

Study: Bacterial protein fragment instigates lung tissue death in pulmonary fibrosis

Study: Bacterial protein fragment instigates lung tissue death in pulmonary fibrosis

Researchers rejuvenate aged human cells with stem cell technology

Researchers rejuvenate aged human cells with stem cell technology

Biogelx announce Alison Clayton as new CEO

Biogelx announce Alison Clayton as new CEO

Old human cells regain youthful strength after rejuvenating protein treatment, study finds

Old human cells regain youthful strength after rejuvenating protein treatment, study finds

Melinjo seed extract may improve obesity and diabetes

Melinjo seed extract may improve obesity and diabetes

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Researchers invent new method to map sugar structures of blood-thinning drug

Researchers invent new method to map sugar structures of blood-thinning drug

Organ-Chips provide human-relevant insights into diseases and toxicity mechanisms

Organ-Chips provide human-relevant insights into diseases and toxicity mechanisms

New understanding of signaling molecule interleukin-2 can guide drug discovery efforts

New understanding of signaling molecule interleukin-2 can guide drug discovery efforts