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Global Fund investigates allegations that donated malaria drugs were stolen, resold in some African countries

After recent research found that some donated malaria drugs are being stolen and sold commercially in several African countries, the Global Fund to Fight AIDS, Tuberculosis and Malaria Communications Director Joe Liden said the group is looking into the situation "in a number of countries," PBS' NewsHour's blog, "The Rundown" reports.

8 Sep 2010

UC San Diego researchers receive grant to study pharmacogenomics for bipolar disorder

An international team, led by University of California, San Diego School of Medicine researchers, has been awarded a $6.5 million grant from the National Institutes of Health (NIH) to study the pharmacogenomics of a key mood-stabilizing drug used to treat bipolar disorder.

8 Sep 2010

Scientists study behaviour of proteins that trigger age-related ailments

Scientists hope to gain insights into a range of age-related ailments, such as dementia, by examining the behaviour of proteins thought to trigger the conditions.Researchers from the University of Edinburgh are to study proteins found in the body to try to find out why these molecules can sometimes clump together as people get older. The clumps interfere with the biological processes that enable the body to function healthily.

8 Sep 2010

Onyx enters commercialization agreement with Ono for carfilzomib and ONX 0912 development program

Onyx Pharmaceuticals, Inc. today announced that it has entered into an exclusive agreement with Ono Pharmaceutical Co., Ltd. to develop and commercialize two compounds from Onyx's proteasome inhibitor development program, carfilzomib and ONX 0912. Under the terms of the agreement, Ono has exclusive rights to develop and commercialize both compounds for all oncology indications in Japan.

8 Sep 2010

Study finds non-hormonal therapies can relieve hot flashes in women with breast cancer

Many women enduring hot flashes experience the heat, sweat and reddened upper body as an uncomfortable inconvenience. However, hot flashes can greatly diminish a woman's quality of life, disrupting sleep at night or causing embarrassment as she goes about her daily business. Many women enduring hot flashes experience the heat, sweat and reddened upper body as an uncomfortable inconvenience. However, hot flashes can greatly diminish a woman's quality of life, disrupting sleep at night or causing embarrassment as she goes about her daily business.

8 Sep 2010

Quick increase of calcium concentration in cells rapidly trigger Aurora-A kinase enzyme activity

Aurora-A kinase (AurA) is an enzyme that is hyperactive in many cancers and drives tumor cell proliferation. Several AurA inhibitors are currently being tested in clinical trials to see if they slow tumor growth. Now, researchers in the Developmental Therapeutics Program at Fox Chase Cancer Center have identified an activation signal for AurA. They report in the September 7 issue of Nature Communications that a quick increase in the calcium concentration in a cell rapidly triggers AurA kinase activity.

8 Sep 2010

K-State University receives patent for procedures to source stem cells from umbilical cord

Kansas State University has been a issued a patent for a plentiful and noncontroversial source of stem cells from a substance in the umbilical cord.

8 Sep 2010

Forest Laboratories' ceftaroline fosamil receives FDA Advisory Committee approval for CABP and cSSSI

Forest Laboratories, Inc. announced that the U.S. Food and Drug Administration's (FDA) Anti-Infective Drugs Advisory Committee voted 21 - 0 in favor of approval of ceftaroline fosamil for the treatment of community acquired bacterial pneumonia (CABP) and voted 18 - 0 in favor of approval for complicated skin and skin structure infections (cSSSI).

8 Sep 2010

BMJ investigation raises concern on rosiglitazone diabetes drug safety

A BMJ investigation into the top-selling diabetes drug rosiglitazone (Avandia) raises concerns about its safety and the whole system by which drugs are evaluated, regulated, and promoted around the world.

8 Sep 2010

Research reveals need for initiatives to prevent, treat substance abuse when fighting violent crime

A new study from Sweden's Karolinska Institutet suggests that bipolar disorder or manic-depressive disorder does not increase the risk of committing violent crime. Instead, the over-representation of individuals with bipolar disorder in violent crime statistics is almost entirely attributable to concurrent substance abuse.

8 Sep 2010

DiaTech Oncology files patent for Drug Discovery to validate cancer treatment

DiaTech Oncology has announced the filing of a patent for Drug Discovery that will provide a new strategy and approach to validate drugs that may be more effective in treating cancer patients

8 Sep 2010

ESPAC-3 trial shows promising results to prevent pancreatic cancer

A major international trial has shown a commonly used chemotherapy drug is as effective at helping prevent pancreatic cancer returning after surgery as the more expensive standard chemotherapy treatment, reveals a study published in the Journal of the American Medical Association today (Wednesday).

8 Sep 2010

Researchers develop new RNA molecule approach to kill cancer cells

Researchers at the California Institute of Technology (Caltech) have engineered a fundamentally new approach to killing cancer cells. The process developed by Niles Pierce, associate professor of applied and computational mathematics and bioengineering at Caltech, and his colleagues uses small RNA molecules that can be programmed to attack only specific cancer cells then, by changing shape, those molecules cause the cancer cells to self destruct.

8 Sep 2010

Yeast can be simple model to study molecular basis of Parkinson’s disease

Yeast could be a powerful ally in the discovery of new therapeutic drugs to treat Parkinson's disease says a scientist presenting his work at the Society for General Microbiology's autumn meeting in Nottingham today.

8 Sep 2010

UCSF scientists to receive two grants for personalized medicine research

UCSF scientists will receive two grants totaling $15.1 million over the next five years to expand their research into how genes affect an individual's response to medication and to strengthen a global network of researchers involved in these efforts.

7 Sep 2010

Morning sickness treatment still elusive: Review

According to experts we are nowhere near establishing safe and effective ways to treat morning sickness. Since the Thalidomide disaster in 1960’s that led to severe birth defects in the infants, this area of research is scary and less explored by many researchers. Despite its name, the vomiting and nausea of morning sickness can occur at any time of the day and affect about half of pregnant women. Between 70% and 85% of women will experience nausea during pregnancy, with about half suffering vomiting. Around 2% will experience it so badly they need to be hospitalised.

7 Sep 2010

Also in Global Health News: India's antibiotic use; Abstinence curriculum in China; Child, maternal health in India; Plumpy'nut; PEPFAR funds to Uganda

"The health ministry has formed a committee to frame a policy for antibiotic use, following an uproar over a Lancet study that traced a drug-resistant bacterial superbug's origins to India," LiveMint.com reports. The panel will also look into the "excessive use of antibiotics among Indians," partly fueled by self-medication, that has increased resistance to the drugs. The article notes that the Indian government "rejected the findings of the report" but has "taken note of a lack of policy on antibiotics" (Pandeya, 9/3).

7 Sep 2010

VirtualScopics enters molecular imaging collaboration with ABX-CRO

VirtualScopics, Inc., a leading provider of quantitative imaging for clinical trials, today announced it has entered into a scientific collaboration, specific to molecular imaging, with ABX-CRO, a Dresden, Germany based full-service contract research organization. The collaboration joins two of the scientific pioneers in the use of advanced imaging for the clinical study of drugs and medical devices.

7 Sep 2010

Promedior initiates PRM-151 Phase 2a clinical study in prevention of scarring post glaucoma filtration surgery

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today that it has initiated a Phase 2a clinical study of PRM-151 to evaluate the efficacy, safety, and tolerability of PRM-151 in preventing post-surgical scarring in glaucoma patients following glaucoma filtration surgery. There currently are no approved drugs for preventing post-surgical scarring in glaucoma, and there are no approved anti-fibrotic drug therapies in the U.S. or Europe for any fibrotic disease.

7 Sep 2010

Idenix Pharmaceuticals receives clinical hold order from FDA for IDX184, IDX320 programs

Idenix Pharmaceuticals, Inc., a biopharmaceutical company engaged in the discovery and development of drugs for the treatment of human viral diseases, today announced that the company received verbal notice on Friday, September 3, 2010 from the U.S. Food and Drug Administration (FDA) that the IDX184 and IDX320 programs have been placed on clinical hold.

7 Sep 2010

Drugs News and Research

Global Fund investigates allegations that donated malaria drugs were stolen, resold in some African countries

UC San Diego researchers receive grant to study pharmacogenomics for bipolar disorder

Scientists study behaviour of proteins that trigger age-related ailments

Onyx enters commercialization agreement with Ono for carfilzomib and ONX 0912 development program

Study finds non-hormonal therapies can relieve hot flashes in women with breast cancer

Quick increase of calcium concentration in cells rapidly trigger Aurora-A kinase enzyme activity

K-State University receives patent for procedures to source stem cells from umbilical cord

Forest Laboratories' ceftaroline fosamil receives FDA Advisory Committee approval for CABP and cSSSI

BMJ investigation raises concern on rosiglitazone diabetes drug safety

Research reveals need for initiatives to prevent, treat substance abuse when fighting violent crime

DiaTech Oncology files patent for Drug Discovery to validate cancer treatment

ESPAC-3 trial shows promising results to prevent pancreatic cancer

Researchers develop new RNA molecule approach to kill cancer cells

Yeast can be simple model to study molecular basis of Parkinson’s disease

UCSF scientists to receive two grants for personalized medicine research

Morning sickness treatment still elusive: Review

Also in Global Health News: India's antibiotic use; Abstinence curriculum in China; Child, maternal health in India; Plumpy'nut; PEPFAR funds to Uganda

VirtualScopics enters molecular imaging collaboration with ABX-CRO

Promedior initiates PRM-151 Phase 2a clinical study in prevention of scarring post glaucoma filtration surgery

Idenix Pharmaceuticals receives clinical hold order from FDA for IDX184, IDX320 programs

Drug Discovery - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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