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Bisphosphonate drugs used to prevent osteoporosis may also help reduce risk of breast cancer

A DRUG commonly used to prevent and treat bones losing density and becoming brittle - known as osteoporosis - may also help reduce the risk of breast cancer by one third or more according to new research published in the British Journal of Cancer today (Wednesday).

3 Mar 2010

AB SCIEX launches mass-spectrometry-based software application to advance lipid biomarker research

AB SCIEX, a global leader in life science analytical technologies, today announced the launch of the first mass-spectrometry-based software application specifically designed to advance the study of lipidomics.

3 Mar 2010

Study suggests mental activity could stave off age-related cognitive and memory decline

UC Irvine neurobiologists are providing the first visual evidence that learning promotes brain health - and, therefore, that mental stimulation could limit the debilitating effects of aging on memory and the mind.

3 Mar 2010

Combination of two targeted therapies effective against subset of gastric cancers: Study

A combination of two targeted therapies already shown to be effective in breast cancer packs an effective one-two punch against a subset of gastric cancers that have a specific genetic mutation, a study at UCLA's Jonsson Comprehensive Cancer Center has found.

3 Mar 2010

Generic version of Flomax Capsules receives FDA approval

The U.S. Food and Drug Administration today approved the first generic version of Flomax Capsules 0.4 mg (tamsulosin hydrochloride) to treat benign prostatic hyperplasia (BPH), a condition in which an enlarged prostate gland causes problems with urination.

2 Mar 2010

National Cancer Institute awards PDS Biotechnology $1.28M phase 2 SBIR contract

PDS Biotechnology Corporation today announced that the company has been awarded a $1.28M phase 2 SBIR contract by the National Cancer Institute division of the US National Institutes of Health. The contract provides funding to complete studies required to file an Investigational New Drug Application (IND) with the FDA for the company's lead human papillomavirus (HPV)-cancer product late in 2010.

2 Mar 2010

InterMune seeks European marketing approval for pirfenidone

InterMune, Inc. today announced that it has submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) seeking approval to market pirfenidone for the treatment of patients with idiopathic pulmonary fibrosis (IPF) in the European Union (EU). Currently, there are no EMA-approved treatments for IPF in the EU.

2 Mar 2010

Synta Pharmaceuticals receives FDA approval for resuming elesclomol clinical development

Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today reported that the U.S. Food and Drug Administration (FDA) has approved resuming clinical development of elesclomol, the Company's first-in-class oxidative stress inducer.

2 Mar 2010

Discovery of two new compounds opens new approach to drug design against HIV protease

A team of researchers at the renowned Scripps Research Institute has discovered two new compounds that prove the existence of new binding sites on HIV protease. Associate Professor C. David Stout, senior author of the study, explained "These results open the door to a whole new approach to drug design against HIV protease," which is an enzyme used by HIV to create new, infectious viral particles.

2 Mar 2010

Latest FCC edition includes standards covering quality and purity for 1,100 food ingredients

New and updated quality standards for ingredients used in functional foods and a host of other food products manufactured, sold and consumed every day are included in the newly released seventh edition of the Food Chemicals Codex. Published by the U.S. Pharmacopeial Convention, the FCC is an internationally recognized compendium of standards that helps ensure the identity, quality, purity and consistency of food ingredients.

2 Mar 2010

Greffex Group signs Strategic Alliance Framework Agreement with UPMC and ISMETT

The Greffex Group of regenerative medicine companies announces the signing of a Strategic Alliance Framework Agreement with UPMC and ISMETT, Italy.

2 Mar 2010

Prenatal cocaine exposure affects sustained attention and self-regulated behavior in children

Children exposed to cocaine in the womb face serious consequences from the drug, but fortunately not in certain critical physical and cognitive areas as previously believed, according to a new comprehensive review of research on the subject from scientists at the University of Maryland School of Medicine. When a pregnant woman uses cocaine, it can interrupt the flow of nutrients and oxygen to the baby, putting such children at risk for premature birth, low birth weight and many other problems.

2 Mar 2010

Sea squirts help in fight against Alzheimer's disease

Alzheimer's disease affects an estimated 27 million people worldwide. It is the most common form of age-related dementia, possibly the most feared disease of old age. There is no cure, and the available drugs only help to relieve symptoms without slowing progression of the disease. One of the characteristic changes in the brains of Alzheimer's patients is the accumulation of plaques and tangles; currently, the best hope for curing or at least slowing the disease lies in developing drugs that target this buildup.

2 Mar 2010

InterSystems Ensemble platform enables first successful electronic transmission of genetic data

InterSystems Corporation, the global leader in software for connected healthcare, today announced that InterSystems Ensemble® was the software platform for the first-ever successful electronic transmission of comprehensive genetic data. The information was sent cross-country from Boston-based Partners HealthCare Center for Personalized Genetic Medicine (PCPGM) to Intermountain HealthCare in Salt Lake City, Utah. The announcement about reaching this milestone in personalized medicine came at the HIMSS10 conference.

2 Mar 2010

Scientists show omega-3 fatty acid and its derivatives kill neuroblastoma cancer cells

The next treatment for cancer might come from fish says a new research report published in the March 2010 print edition of the FASEB Journal (http://www.fasebj.org). In the report, scientists show that the omega-3 fatty acid, "docosahexaenoic acid" or "DHA," and its derivatives in the body kill neuroblastoma cancer cells.

2 Mar 2010

Simvastatin impairs ability of macrophages to kill pathogens, and enhances cytokine production

Simvastatin might help us control our cholesterol, but when it comes to infection, it's an entirely different story says a new research study published in the Journal of Leukocyte Biology. In the research report, scientists from Italy show that simvastatin delivers a one-two punch to the immune system. First it impairs the ability of specialized immune cells, called macrophages, to kill pathogens. Then, it enhances production of molecules, called cytokines, which trigger and sustain inflammation.

2 Mar 2010

Merck's Isentress HIV/AIDS drug pricing: CalSTRS and CalPERS express concern

Today AIDS Healthcare Foundation (AHF) announced that the two largest public pension funds in the nation, the California State Teachers' Retirement System (CalSTRS) and the California Public Employees’ Retirement System (CalPERS), have sent letters to Merck and Co. Pharmaceuticals expressing concern over the company’s pricing for its key HIV/AIDS drug, Isentress—now the most expensive first-line AIDS treatment in the U.S.

2 Mar 2010

States continue to wrestle with Medicaid spending, budget issues; Utah legislation would criminalize illegal abortion

Cincinnati Business Courier: Ohio Gov. Ted Strickland has signed a bill that will extend the state's mini-COBRA program from 12 to 15 months for small-business employees, according to a report in Columbus Business First (3/1).

2 Mar 2010

Study finds most HIV prevention, treatment, care efforts overlook IDUs

A systematic review of HIV prevention, treatment and care for injecting drug users (IDUs) throughout the world, published Monday in the journal Lancet, found that international efforts to fight the disease are largely overlooking this population, the Australian Associated Press/Sydney Morning Herald reports (Rose, 3/1).

2 Mar 2010

PTSD drug: Cannabis Science to file first application for FDA clinical trials

Cannabis Science Inc., a pharmaceutical cannabis company in the US, is pleased to announce that it now has the results of its survey of more than 1,300 individuals with PTSD, including a large cohort of veterans. The survey was conducted by Cannabis Science Advisory Board member Dr. Mitch Earleywine PhD. of the State University of New York (Albany).

2 Mar 2010

Drugs News and Research

Bisphosphonate drugs used to prevent osteoporosis may also help reduce risk of breast cancer

AB SCIEX launches mass-spectrometry-based software application to advance lipid biomarker research

Study suggests mental activity could stave off age-related cognitive and memory decline

Combination of two targeted therapies effective against subset of gastric cancers: Study

Generic version of Flomax Capsules receives FDA approval

National Cancer Institute awards PDS Biotechnology $1.28M phase 2 SBIR contract

InterMune seeks European marketing approval for pirfenidone

Synta Pharmaceuticals receives FDA approval for resuming elesclomol clinical development

Discovery of two new compounds opens new approach to drug design against HIV protease

Latest FCC edition includes standards covering quality and purity for 1,100 food ingredients

Greffex Group signs Strategic Alliance Framework Agreement with UPMC and ISMETT

Prenatal cocaine exposure affects sustained attention and self-regulated behavior in children

Sea squirts help in fight against Alzheimer's disease

InterSystems Ensemble platform enables first successful electronic transmission of genetic data

Scientists show omega-3 fatty acid and its derivatives kill neuroblastoma cancer cells

Simvastatin impairs ability of macrophages to kill pathogens, and enhances cytokine production

Merck's Isentress HIV/AIDS drug pricing: CalSTRS and CalPERS express concern

States continue to wrestle with Medicaid spending, budget issues; Utah legislation would criminalize illegal abortion

Study finds most HIV prevention, treatment, care efforts overlook IDUs

PTSD drug: Cannabis Science to file first application for FDA clinical trials

Drug Discovery - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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