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Fluorodeoxyglucose positron emission tomography to help determine whether cognitive impairment will lead to Alzheimer's

With nearly 10 million baby boomers at risk for developing Alzheimer's disease, researchers are taking a closer look at a condition known as mild cognitive impairment.

3 Apr 2008

Mouse calls help search for emotion-controlling genes

Scientists have long known that emotions and other personality traits and disorders run together in families.

3 Apr 2008

Genetic mutations tied to immune comeback during therapy for HIV-1

Researchers with the Infectious Disease Clinical Research Program (IDCRP) at the Uniformed Services University of the Health Sciences (USU) here and the University of Texas Health Science Center at San Antonio have published a patient outcome study in the March 30 online edition of Nature Medicine that may signal a need for a change of thought in the management of HIV.

3 Apr 2008

Potential new treatments for polycystic kidney disease

A family of small molecules called CFTR inhibitors show promising effects in slowing the progression of polycystic kidney disease (PKD), the most common genetic disease of the kidneys, according to preliminary research reported in the July 2008 issue of the Journal of the American Society Nephrology.

3 Apr 2008

De-marrowing helps bones mend faster

Could you strengthen bones and speed up recovery after fractures and breaks simply by removing some bone marrow with a syringe?

3 Apr 2008

How to reduce fibromyalgia pain

Pain all over, fatigue and difficulty sleeping -- and no measurable answer for what could be wrong.

3 Apr 2008

Cellular grafting procedure helps young patients with knee disorder get active

At 14 years old, Adam Vasser of Los Altos, Calif., was an active kid who loved baseball.

2 Apr 2008

Light-powered nanomachine kills cancer cells

Researchers from the Nano Machine Center at the California NanoSystems Institute at UCLA have developed a novel type of nanomachine that can capture and store anticancer drugs inside tiny pores and release them into cancer cells in response to light.

2 Apr 2008

Scientists discover how polyketides form their ringlike shape

Many top-selling drugs used to treat cancer and lower cholesterol are made from organic compounds called polyketides, which are found in nature but historically difficult for chemists to alter and reproduce in large quantities.

2 Apr 2008

Restrictive drug policies often cause schizophrenic patients to discontinue medication

Policies requiring authorization before physicians can prescribe newer medications to schizophrenic patients may be counter-productive.

2 Apr 2008

Prednisone tablets less variable than marketed drugs

The U.S. Pharmacopeial (USP) Convention has announced results of a study comparing the dissolution variability of USP Prednisone Lot P Reference Standard tablets to two marketed drugs.

2 Apr 2008

Stimulant treatment for ADHD does not contribute to substance abuse later in life

Treating children as early as age six or seven with stimulants for Attention Deficit Hyperactivity Disorder (ADHD) is not likely to increase risk of substance abuse as adults, according to two studies funded by the National Institutes of Health (NIH).

2 Apr 2008

Bosentan drugs offers new approach to limiting organ damage in sickle cell disease

Sickle cell disease (SCD) is so called because of the abnormal sickle shape of the red blood cells in individuals with this blood disorder.

2 Apr 2008

From algae to parasites: new 'missing link' species found in Sydney Harbour

It's not often that brown algae is considered exciting or revolutionary, but Associate Professor Dee Carter from the School of Molecular and Microbial Biosciences at the University of Sydney and her former PhD student, Robert Moore, have found a new species of single-celled brown algae that is an evolutionary missing link.

2 Apr 2008

Illicit drug use increasingly glamorized in rap music

Rap music has gone from an art form that largely warned against the dangers of substance abuse to one that often glorifies illegal drug use, according to the first systematic social science study of the genre covering nearly two decades.

2 Apr 2008

Distinguishing non-TB pulmonary disease from TB

A diagnostic kit shows new promise for distinguishing between tuberculosis (TB) and its infections from disease caused by related mycobacteria family, which mimic TB and other lung disease in symptoms but require distinctly different clinical treatments.

2 Apr 2008

New breakthrough discovery on TB

Medical scientists from the University of Leicester, together with colleagues from St Georges, University of London, funded principally by the Medical Research Council (MRC) and The Wellcome Trust, have published details of a new breakthrough discovery on TB.

1 Apr 2008

A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics

Results of a randomised trial published in PLoS Medicine show no benefit in cognitive or neuropsychiatric outcomes from continuing neuroleptic drugs in patients with Alzheimer's disease.

1 Apr 2008

New research shows benefits of ultrasound contrast agents outweigh potential risk to heart patients

A Saint Louis University cardiologist called upon the U.S. Food and Drug Administration (FDA) today to reconsider a strong warning it recently placed on a diagnostic tool, stating that the warning could prevent doctors from detecting life-threatening cardiac events.

1 Apr 2008

New genetic clues to diabetes

An international team that included scientists from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today reported it has identified six more genetic variants involved in type 2 diabetes, boosting to 16 the total number of genetic risk factors associated with increased risk of the disease.

1 Apr 2008