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Tumor cell activity may provide clues for treating breast cancer in young women

When women under 50 develop breast cancer the disease tends to be more aggressive and less responsive to treatment than when it occurs in older women.

5 Jun 2007

Circulating tumor cells predict how prostate cancer patients do with chemotherapy

The number of tumor cells circulating in the bloodstream of patients with metastatic, hormone-resistant, prostate cancer can predict how they will do with chemotherapy, according to results of an international trial.

5 Jun 2007

New precise method for studying the DNA binding of small molecules

Northeastern University professor Mark C. Williams and colleague Ioana Vladescu have discovered a novel method for studying the DNA binding of small molecules with unprecedented accuracy.

5 Jun 2007

Study shows combination improves survival of metastatic melanoma patients

Two chemotherapy drugs combined with an agent that prevents the growth of blood vessels significantly delayed the spread of tumors in patients with metastatic melanoma, according to study findings presented at the 2007 American Association of Clinical Oncology (ASCO) Annual Meeting.

5 Jun 2007

PET/CT best for monitoring Crohn's disease

The molecular imaging power of PET/CT is invaluable in noninvasively monitoring Crohn's disease,a chronic inflammatory disease of the gastrointestinal tract that mainly affects young people, according to a study released by Belgian scientists at the 54th Annual Meeting of SNM.

5 Jun 2007

Key source of chronic pain appears to be an old memory trace stuck in the prefrontal cortex

Why do so many people continue to suffer from life-altering, chronic pain long after their injuries have actually healed"

5 Jun 2007

Gabapentin reduces hot flashes in men receiving androgen deprivation therapy

North Central Cancer Treatment Group ( http://ncctg/ ) researchers based at Mayo Clinic ( http://www.mayo.edu/ ) in Rochester, Minn., have discovered that low doses of a drug used to prevent epileptic seizures and to treat nerve pain caused by shingles substantially reduces hot flashes in patients who are undergoing anti-hormonal treatment, or androgen-deprivation therapy, for prostate cancer.

5 Jun 2007

Results of phase II studies of pazopanib

GlaxoSmithKline (GSK) has announced results from ongoing Phase II studies of pazopanib in advanced or metastatic renal cell carcinoma (RCC) and ovarian cancer.

5 Jun 2007

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in mice

Rats with erectile dysfunction, or ED, that were injected with a gene therapy vector containing either of two nerve growth factors were able to regain normal function after four weeks, according to a study conducted by University of Pittsburgh School of Medicine researchers.

5 Jun 2007

New FDA committee to address risk communication

The U.S. Food and Drug Administration (FDA) today announced a new advisory committee designed to counsel the agency on how to strengthen the communication of risks and benefits of FDA-regulated products to the public.

5 Jun 2007

Predicting treatment responses earlier for brain tumor patients

Using metabolic or molecular imaging to measure brain tumor patients' response to treatment is a powerful predictor of survival, notes a first-of-its-kind study presented at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

5 Jun 2007

Drug lapatinib shows activity against brain metastases

The drug lapatinib shrank tumors and slowed progression of brain metastases in some patients with advanced breast cancer, according to results of a clinical trial presented by Dana-Farber Cancer Institute scientists at the annual meeting of the American Society of Clinical Oncology.

5 Jun 2007

Dasatinib shows promise as first treatment for chronic myelogenous leukemia

An established second-line drug for chronic myelogenous leukemia has high response rates when given to newly diagnosed patients as their first therapy for the disease, according to early results from a Phase II clinical trial at The University of Texas M. D. Anderson Cancer Center.

5 Jun 2007

Chemotherapy may enhance the effectiveness of the vaccines

Chemotherapy temporarily hinders the body's immune response, creating a concern that it may interfere with the promising new cancer vaccines being used against brain tumors.

5 Jun 2007

Modafinil (Provigil) alleviates post-chemotherapy fogginess

A drug described by some people as a genius pill for enhancing cognitive function provided relief to a small group of Rochester breast cancer survivors who were coping with a side effect known as chemo-brain, according to a University of Rochester Medical Center study.

5 Jun 2007

Sertraline does not improve symptoms in some cancer patients without major depression

The established antidepressant sertraline does not improve symptoms, wellbeing or survival in patients with advanced cancer who do not have major depression.

5 Jun 2007

AMPAKINE drugs may provide protection from drug-induced respiratory depression

Drug-induced respiratory depression is a life-threatening condition caused by analgesic, hypnotic, and anesthesia medications.

5 Jun 2007

Shark fin no benefit to cancer victims

In the latest research into the benefits of alternative therapies for cancer, shark cartilage did not help patients with lung cancer live longer but ginseng and flaxseed appeared to offer some benefit to cancer patients.

3 Jun 2007

Fugitive TB patient's father-in-law a TB expert at the CDC

The air traveller who flitted across Europe in a bid to avoid authorities because he had a rare form of tuberculosis (TB), apparently has a father-in-law who is a tuberculosis researcher for the Centers for Disease Control and Prevention (CDC) in the U.S.

3 Jun 2007

VA tops private hospitals in infection-control study

Department of Veterans Affairs (VA) medical centers are more likely than non-VA hospitals to follow recommendations for preventing bloodstream infections associated with central venous catheters, says a survey of more than 500 U.S. health care centers.

3 Jun 2007