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Artemisinin combination therapies have potential to be one of the major public health interventions for Africa in this decade

Despite changes in policy in many African countries, most cases of malaria are still treated with old drugs that often fail, say researchers the British Medical Journal.

3 Oct 2005

No specific antiretroviral drug-related "Crix belly" syndrome

Contrary to the concerns of many HIV-infected patients, there appears to be no specific antiretroviral drug-related "syndrome" of changes in body fat distribution in men wherein leg and arm fat decrease as belly fat increases, reports a study in the October issue of Journal of Acquired Immune Deficiency Syndromes (JAIDS).

28 Sep 2005

Nicotine has an unusual psychological property that may drive dependence

Associate Professor Athina Markou, Ph.D., who is in the Scripps Research Molecular and Integrative Neurosciences Department at Scripps Research’s La Jolla Campus, and Paul Kenny, Ph.D., a former Research Associate in her laboratory, report in an upcoming issue of the journal Neuropsychopharmacology that nicotine has an unusual psychological property that may drive dependence.

28 Sep 2005

Researchers look at pharmacogenomics

When patients receive chemotherapy, 15 percent will have severe side effects while 85 percent will not - even though they're given the same relative dose.

28 Sep 2005

Nanoparticles as an invisible diet

Utah State University researchers are in the early stages of scientifically tricking the body into eating less and finding a treatment for obesity without dangerous side effects.

28 Sep 2005

New Stat1 and interferon findings

By altering a molecule called Stat1, which is involved in cellular immune signaling, scientists have succeeded in making the molecule more responsive and thus more efficient. This old protein with a new twist may eventually be used to improve the body's defense against infection.

28 Sep 2005

Fruit fly discovery could lead to a completely new approach to tackling some cancers

Scientists studying the humble fruit fly have found a family of proteins that enhances the sensitivity of a cell to a hormone that can trigger abnormal growth and cancer. Their discovery could lead to a completely new approach to tackling some cancers and the development of new drugs to stop uncontrolled growth in a wide variety of tumour cells.

28 Sep 2005

Emergence of "POZ Parties"

The emergence of "POZ Parties" - parties exclusively for HIV positive men to meet other HIV positive men for sex - signals the potential to spread HIV "superinfection,"suggests research in Sexually Transmitted Infections.

28 Sep 2005

Drug-releasing intravaginal ring could help prevent women from contracting HIV infection

The silicone vaginal ring steadily releases aciclovir: a treatment for genital herpes. It is known that women with genital herpes are at increased risk of HIV infection because the genital blisters caused by the infection increase the transmissibility of sexually acquired HIV.

28 Sep 2005

Survival of heart attack patients placed on beta-blocker therapy corresponds to specific variations in their genes

Survival of heart attack and unstable angina patients placed on beta-blocker therapy corresponds to specific variations in their genes, according to a study by researchers at Washington University School of Medicine in St. Louis and the Mid America Heart Institute in Kansas City.

27 Sep 2005

Irritable Bowel Syndrome (IBS) treatment using hypnotherapy

Up to eight million people in Britain suffer from IBS, with symptoms including diarrhoea, pain and bloating. The condition can seriously affect sufferers' quality of life and finding treatment can be difficult, leading many doctors to feel they can do little to help.

From The University of Manchester 27 Sep 2005

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network has launched its second clinical trial to study NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol. The first trial, launched in January of this year, focuses on adults, while the second trial studies the disease in children.

27 Sep 2005

Gene variants and beta-blockers associated with increased risk of death

Patients with certain gene variants who were prescribed beta-blocker drugs after acute coronary syndrome (ACS) had an increased risk of death over the next three years, according to a study in the September 28 issue of Journal of the American Medical Association (JAMA).

27 Sep 2005

Veggies reduce the risk of developing lung cancer in smokers

Eating vegetables and other foods that have weak estrogen-like activity appears to reduce the risk of developing lung cancer in smokers - as well as in non-smokers, say researchers at The University of Texas M. D. Anderson Cancer Center.

27 Sep 2005

Possibility of tailored treatments for addiction based on how a person's genes behave

Scientists have learned how a genetic variation long suspected in making some people susceptible to alcoholism and narcotic drug addiction actually does so.

27 Sep 2005

Governments considering reclassifying some drugs from prescription to over-the-counter status

Governments in several countries with public Pharmacare and in a few provinces in Canada are considering reclassifying some drugs from prescription to over-the-counter status. In a Canadian Medical Association Journal essay, Lynd and colleagues comment on the economic effects of such changes.

27 Sep 2005

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Pharmaceutical companies around the world still come knocking on Renato Baserga, M.D.,'s door. And for good reason.

27 Sep 2005

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Johns Hopkins scientists have discovered that a drug currently being tested against cancers might help children with a rare, fatal condition called Hutchinson-Gilford progeria syndrome, which causes rapid, premature aging.

27 Sep 2005

Computer program helps explain how the same proteins can play different roles in a wide range of cellular processes

University of California, San Diego biochemists have developed a computer program that helps explain a long-standing mystery: how the same proteins can play different roles in a wide range of cellular processes, including those leading to immune responses and cancer.

27 Sep 2005

Pulsing heart cell provides clues into how heart disease develops

A pulsing heart cell is giving Oregon Health & Science University researchers insight into how it sends and receives signals, and that's providing clues into how heart disease and other disorders develop.

27 Sep 2005

Drugs News and Research

Artemisinin combination therapies have potential to be one of the major public health interventions for Africa in this decade

No specific antiretroviral drug-related "Crix belly" syndrome

Nicotine has an unusual psychological property that may drive dependence

Researchers look at pharmacogenomics

Nanoparticles as an invisible diet

New Stat1 and interferon findings

Fruit fly discovery could lead to a completely new approach to tackling some cancers

Emergence of "POZ Parties"

Drug-releasing intravaginal ring could help prevent women from contracting HIV infection

Survival of heart attack patients placed on beta-blocker therapy corresponds to specific variations in their genes

Irritable Bowel Syndrome (IBS) treatment using hypnotherapy

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

Gene variants and beta-blockers associated with increased risk of death

Veggies reduce the risk of developing lung cancer in smokers

Possibility of tailored treatments for addiction based on how a person's genes behave

Governments considering reclassifying some drugs from prescription to over-the-counter status

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Computer program helps explain how the same proteins can play different roles in a wide range of cellular processes

Pulsing heart cell provides clues into how heart disease develops

Drug Discovery - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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