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Many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals

A new study finds many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals, and says investigators should be committed not just to finding novel compounds, but also to make sure final results of their studies be disseminated to the medical community.

22 Aug 2005

Detailed picture of migraines

Every eight adult Swede suffers from migraine. Using a new method, researchers at Göteborg have managed for the first time ever to provide a detailed picture of an untreated attack. This will be of great significance for the development of new forms of treatment.

22 Aug 2005

New guidelines to battle heart failure

Early diagnosis and new treatments can help battle heart failure -- a growing national problem that causes 1 million hospital admissions each year, according to new guidelines released by the American College of Cardiology (ACC) and the American Heart Association (AHA).

22 Aug 2005

Discovery of new gene FANCM sheds light on repair of damaged DNA

National Institute on Aging (NIA) researchers have discovered a new gene, FANCM, which sheds light on an important pathway involved in the repair of damaged DNA.

22 Aug 2005

Phase I cancer findings under-reported

Phase I cancer studies, trials that are conducted to determine the safety and maximum dose of a new agent, are under-reported in peer-reviewed journals - a trend that could ultimately delay scientific progress and negatively affect patient care, say researchers at The University of Texas M. D. Anderson Cancer Center in a new study out today (Mon., Aug, 22) online in Cancer.

22 Aug 2005

Poorer countries to benefit from reinstatement of 7 generic AIDS drugs to WHO's list

India's Ranbaxy Laboratories, seven anti- AIDS drugs, have been added to World Health Organisation's (WHO) prequalification list for use in poor countries.

21 Aug 2005

Mom and Dad's disapproval a greater deterrant than the law when it comes to drugs and alcohol

Latest survey shows steep rise in students attending schools with access to drugs.

21 Aug 2005

Mutations in the targets of designer drugs critically influence their effectiveness

Two designer cancer drugs differed dramatically in a laboratory test comparing their ability to shut down a mutant, overactive growth signal in lung cancer cells, reports a team headed by scientists at the Dana-Farber Cancer Institute.

18 Aug 2005

Defects in newly discovered pathway may be an overlooked cause of anemia

Researchers studying zebrafish that die from anemia have discovered a new pathway for the synthesis of heme, the deep red, iron-containing molecule that is a component of hemoglobin and myoglobin.

18 Aug 2005

Slower care for heart attack patients treated after hours and on weekends

Heart attack patients treated with primary percutaneous intervention (PCI) at hospitals after hours and on weekends wait longer to receive clot busters and other treatments and have a higher risk of death than those treated during regular hospital hours

18 Aug 2005

Global prevalence of kidney failure among critically ill patients

A multinational study has found that 5 to 6 percent of patients in intensive care units experience acute kidney failure, and about 60 percent of these patients die in the hospital, according to an article in the August 17 issue of JAMA: The Journal of the American Medical Association.

18 Aug 2005

Separate studies produce conflicting results on race and gender disparities in U.S. health system

Two newly released studies in the U.S. have to some extent come to conflicting results. According to one study, by researchers at Emory University, attempts over the last decade to address race and gender disparities in the treatment of U.S. patients hospitalized for heart attacks, still in some respects raise cause for concern.

18 Aug 2005

Treatment of U.S. patients hospitalized for heart attacks continues to vary according to sex and race

Despite a decade of initiatives to remedy health disparities in cardiovascular medicine, at least some aspects of the treatment of U.S. patients hospitalized for heart attacks continues to vary according to sex and race, according to a study by researchers at Emory University in collaboration with Yale University and other centers.

17 Aug 2005

Common non-aspirin painkillers linked to high blood pressure in women

Women who consume higher doses of non-aspirin painkillers are much more likely to develop high blood pressure than women who do not use them, according to research reported in Hypertension: Journal of the American Heart Association.

17 Aug 2005

Low hemoglobin levels are a predictor of increased risk of death among heart failure patients

Hemoglobin (Hgb) is the major substance in red blood cells, and its level indicates the blood's ability to carry oxygen throughout the body. Studies have shown that low hemoglobin, which may result in anemia, is more common among patients with heart failure than it is among people in the general population.

17 Aug 2005

Stem Cell Sciences to commercialise breakthrough in neural stem cell technology

Stem Cell Sciences has announced that it has an exclusive license to a new patented technology to derive and grow neural stem cells. This technology has been licensed from the University of Edinburgh.

16 Aug 2005

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Weight control protein may yield new approaches for treating obesity and type 2 diabetes

The findings in mice further suggest that particular variants of the protein SH2-B might underlie obesity in humans, the researchers said.

16 Aug 2005

Decline in energy production by mitochondria appears to be a key problem leading to insulin resistance

A detectable decline in energy production by mitochondria - the organelles that are the cell's furnace for energy production - seems to be a key problem leading to insulin resistance, and thus to type 2 diabetes, according to studies by Howard Hughes Medical Institute researchers.

16 Aug 2005

New study shows even non-prescription painkillers raise blood pressure in women

According to a new U.S. study women who take higher doses of common, over-the-counter painkillers, such as Ibuprofen and even Tylenol, have higher blood pressure than women who do not.

16 Aug 2005

Drugs News and Research

Many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals

Detailed picture of migraines

New guidelines to battle heart failure

Discovery of new gene FANCM sheds light on repair of damaged DNA

Phase I cancer findings under-reported

Poorer countries to benefit from reinstatement of 7 generic AIDS drugs to WHO's list

Mom and Dad's disapproval a greater deterrant than the law when it comes to drugs and alcohol

Mutations in the targets of designer drugs critically influence their effectiveness

Defects in newly discovered pathway may be an overlooked cause of anemia

Slower care for heart attack patients treated after hours and on weekends

Global prevalence of kidney failure among critically ill patients

Separate studies produce conflicting results on race and gender disparities in U.S. health system

Treatment of U.S. patients hospitalized for heart attacks continues to vary according to sex and race

Common non-aspirin painkillers linked to high blood pressure in women

Low hemoglobin levels are a predictor of increased risk of death among heart failure patients

Stem Cell Sciences to commercialise breakthrough in neural stem cell technology

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Weight control protein may yield new approaches for treating obesity and type 2 diabetes

Decline in energy production by mitochondria appears to be a key problem leading to insulin resistance

New study shows even non-prescription painkillers raise blood pressure in women

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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